Low Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome: A Paradigm Shift in Mechanical Ventilation by Jed Lipes, Azadeh Bojmehrani, Francois Lellouche

“…Protective ventilation with low tidal volume has been shown to reduce morbidity and mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). …”
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Umbilical Cord Hematoma: A Case Report and Review of the Literature by Gennaro Scutiero, Bernardi Giulia, Piergiorgio Iannone, Luigi Nappi, Danila Morano, Pantaleo Greco

“…Spontaneous umbilical cord hematoma is a rare complication of pregnancy which represents a serious cause of fetal morbidity and mortality. There are many risk factors such as morphologic anomalies, infections, vessel wall abnormalities, iatrogenic causes, and traction or torsion of the cord, but the exact etiology is still unknown. …”
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The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper by Andrew E Simor, Mark Loeb, the CIDS/CAMM Guidelines Committee

“…Several studies have confirmed that MRSA infection is associated with increased morbidity and mortality compared with infections caused by susceptible strains, even when the presence of comorbidities is accounted for. …”
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Aortic Valve Fibroelastoma Masquerading as Transient Ischaemic Attack by Penelope-Anne Gowland, Ragheb Hasan

“…Although histologically papillary fibroelastomas are described as benign, they carry with them considerable risk of morbidity and mortality. This patient experienced recurrent transient ischemic attacks (TIAs’). …”
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Diagnosis and treatment of cerebral vasospasm after subarachnoid hemorrhage by Youssef Fardos, Daniel Mattimore, Wesam Andraous, Sofia Geralemou, Sergio Bergese, Ana Costa

“… Cerebral vasospasm after subarachnoid hemorrhage leads to delayed cerebral ischemia and contributes to increased morbidity and mortality. Stroke secondary to vasospasm accounts for almost half of the early deaths after subarachnoid hemorrhage. …”
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PULMONARY EMBOLISM IN THE PRACTICE OF AN OBSTETRICIAN-GYNECOLOGIST (CLINICAL CASE) by Елена Владимировна Рудаева, Юлия Валерьевна Васютинская, Любовь Борисовна Николаева, Светлана Ивановна Елгина, Кира Борисовна Мозес

“…It is a major cause of pregnancy-related morbidity and mortality in any trimester. The incidence of PE during pregnancy is estimated to be approximately 1 in 1000 pregnancies. …”
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Tricuspid Regurgitation in the Setting of Cardiac Implantable Electronic Devices by Omar M. Aldaas, MD, Gary Ma, MD, Quan Bui, MD, Ryan R. Reeves, MD, Ulrika Birgersdotter-Green, MD

“…Although generally well-tolerated and safe, implantation of CIEDs may result in or worsen tricuspid regurgitation (TR), which is associated with a higher risk of morbidity and mortality. Several mechanisms of TR following device implantation have been proposed, and multiple diagnostic tests, percutaneous and surgical interventions, and alternative pacing methods have been developed to address this. …”
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Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers by Paulina Nadziakiewicz, Wioletta Szczurek-Wasilewicz, Bożena Szyguła-Jurkiewicz

“…Heart failure (HF) is a common condition and one of the main morbidity and mortality factors in elderly patients. …”
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Melanoma Disparities among US Hispanics: Use of the Social Ecological Model to Contextualize Reasons for Inequitable Outcomes and Frame a Research Agenda by Valerie M. Harvey, Charlene W. Oldfield, Jarvis T. Chen, Karl Eschbach

“…While non-Hispanic whites have higher incidence rates of melanoma, Hispanics are typically diagnosed at later disease stages and suffer higher morbidity and mortality. Currently, there is a paucity of literature investigating the root causes underlying these trends among Hispanics. …”
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Postsurgical Prosthetic Rehabilitation after Mandibular Ameloblastoma Resection: A 7-Year Follow-Up Case Report by C. Moreno-Soriano, A. Estrugo-Devesa, P. Castañeda-Vega, E. Jané-Salas, J. López-López

“…Postsurgical defects generate a significant morbidity that needs reconstruction and oral rehabilitation to restore the oral functions. …”
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Alcohol-induced liver disease: primary and secondary prevention by S. V. Plyusnin, K. V. Ivashkin, A. N. Bobrov, S. A. Belyakin, I. V. Plyusnina

“…Prompt change of situation with alcohol abuse is required for reduction of morbidity and mortality. Preventive actions should be directed on change of embedded stereotypes of doctors and population in relation to alcohol intake.…”
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COMPLICATIONS AFTER HEPATECTOMY by Claudemiro Quireze Junior, Fabricio Ferreira Coelho, Agnaldo Soares Lima, Hugo Pinto Marques, Martin Palavecino, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira

“…Surgery impacts on the long-term prognosis and complications adversely affect oncological results. The actual morbidity involving this scenario is debatable and estimated to be ranging from 15% to 50%. …”
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Intermediate-High Risk Pulmonary Embolism: The Use of Riociguat and Inferior Vena Cava Filter in a Situation of Recurrent Embolism following Insufficient Anticoagulation and Fibrin... by Anh Khoi Vo, Håkon Reikvam, Helga Midtbø, Jan Ludvig Wirsching, Øyvind Bruserud, Øystein Wendelbo

“…Pulmonary embolism (PE) is associated with serious morbidity and mortality. In this case report, we describe a hemodynamically stable patient with submassive PE and a large thrombus in the inferior vena cava (IVC) protruding into the right atrium (RA), complicated by severe respiratory failure, elevated troponin T (TnT), and right ventricular (RV) dysfunction. …”
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Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass by Juan D. Salcedo, Jordan S. Goldstein, Jose M. Quinonez, Maria Antonietta Mosetti

“…An early diagnosis and intervention are crucial to decrease morbidity and mortality.…”
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Can Surgery Be Avoided? Exclusive Antibiotic Treatment for Pelvic Actinomycosis by M. P. Ruiz, E. M. Williams, C. M. Markey, A. M. Johnson, P. B. Morales-Ramirez

“…Due to its unspecific clinical and radiologic findings, it can mimic pelvic or intra-abdominal malignancy leading to mutilating surgery of high morbidity. Rarely, diagnosis is made preoperatively and in most cases surgical intervention is necessary. …”
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Canadian Guidelines for the Management of Acute Exacerbations of Chronic Bronchitis by Meyer S Balter, Jacques La Forge, Donald E Low, Lionel Mandell, Ronald F Grossman, the Chronic Bronchitis Working Group

“…Acute exacerbations of chronic bronchitis (AECB) account for over 1.5 million physician visits annually in Canada and are a cause of significant morbidity and mortality. This document represents a joint effort between respirologists, microbiologists, infectious disease specialists and family physicians to update the Canadian AECB guidelines published in 1994. …”
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An Early Abdominal Wall Ectopic Pregnancy Successfully Treated with Ultrasound Guided Intralesional Methotrexate: A Case Report by Paynesha M. Anderson, Erin K. Opfer, Jeanne M. Busch, Everett F. Magann

“…Direct intralesional injection of methotrexate as the next treatment choice may avoid the morbidity linked with operative management.…”
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Novel Interventional Approaches for ALI/ARDS: Cell-Based Gene Therapy by Ying-Gang Zhu, Jie-Ming Qu, Jing Zhang, Hong-Ni Jiang, Jin-Fu Xu

“…Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), continue to be a major cause of morbidity and mortality in critically ill patients. …”
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Prevention and Management of Gastroesophageal Varices in Cirrhosis by Yen-I Chen, Peter Ghali

“…Variceal hemorrhage is one of the major complications of liver cirrhosis associated with significant mortality and morbidity. Its management has evolved over the past decade and has substantially reduced the rate of first and recurrent bleeding while decreasing mortality. …”
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Pathologic Fractures: A Neglected Clinical Feature of Parathyroid Adenoma by Hassan Abshirini, Iran Rashidi, Nader Saki

“…Here, we present a 48-year-old man with multiple typical fractures in long bones and a single adenoma in his right inferior parathyroid gland. pHPT is a severe, symptomatic disease with serious complications and high morbidity in Iran. Advanced skeletal disease is the most common pattern of presentation.…”
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