Polypragmasy at treatment of <i>H. pylori</i> infection in patients with concomitant diseases of other organs and systems. How to prevent side effects related to drug interactions? by S. G. Burkov, N. V. Shornikova

“…Authors believe, taking into account available data on drug interactions, that at patients with multiple morbidity pantoprazole is preferable to other antisecretory agents.…”
Get full text

Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis by Manuela Di Franco, Bruno Lucchino, Fabrizio Conti, Guido Valesini, Francesca Romana Spinelli

“…Cardiovascular disease is the main cause of morbidity and mortality in rheumatoid arthritis (RA). …”
Get full text

Patients with Diabetes Complicated by Peripheral Artery Disease: the Current State of Knowledge on Physiotherapy Interventions by Katarzyna Hap, Karolina Biernat, Grzegorz Konieczny

“…Diabetes mellitus (DM) is one of the major public health problems that account for morbidity, mortality, and disability worldwide. The presence of DM increases the risk of peripheral artery disease (PAD), as well as accelerates its course, making these patients more susceptible to ischemic events and impaired functional status. …”
Get full text

Glucocorticosteroid in Treatment of Severe Pneumonia by Felinda Ariani, Kaixiong Liu, Zhang Jing, Jieming Qu

“…Airway diseases such as pneumonia constitute a major health burden on a global scale; untreated pneumonia may develop to severe pneumonia and consequently lead to to fatal episodes of mortality and morbidity. The balance between inflammatory mediators is key for the outcome of the pulmonary infection; elimination of invading pathogen was marked by the release of cytokines and other inflammatory mediators from alveolar macrophages and glucocorticoid steroids (GCs) acting on the inflammatory component. …”
Get full text

A Rare Clinical Case: Giant Splenic Artery Aneurysm and Its Successful Endovascular Treatment by Alptekin Yasim, Hakan Kara, Erdinc Eroglu

“…Due to high mortality and morbidity in open surgery, endovascular treatment of giant splenic artery aneurysm is a better treatment option.…”
Get full text

Diabetic Foot Care Plan by Gordon Dow, The Diabetic Foot Care Plan Working Group

“…Diabetes mellitus is the number one cause of limb loss in North America, and is associated with growing, unacceptable rates of morbidity, mortality and economic loss. Approximately 80% of these amputations are preceded by the development of foot ulceration. …”
Get full text

Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury by Jingying Zhou, Xue Huo, Benson O. A. Botchway, Luyao Xu, Xiaofang Meng, Songou Zhang, Xuehong Liu

“…Spinal cord injury (SCI) causes a high rate of morbidity and disability. The clinical features of SCI are divided into acute, subacute, and chronic phases according to its pathophysiological events. …”
Get full text

Complete remission in an advanced hepatocellular carcinoma patient with AXIN1 mutation after systemic therapy: A case report by Yihong Ran, Xiaozhun Huang, Xu Che, Dong Chen

“…Primary hepatocellular carcinoma (HCC) is a common malignancy with high morbidity and mortality. Despite progress in systemic therapies, survival in advanced HCC remains poor due to patient heterogeneity and individual differences, necessitating a personalized approach rather than relying solely on guidelines. …”
Get full text

Sinusoidal Obstruction Syndrome (SOS) in Multiple Myeloma with Renal Failure by Urvi A. Shah, Sengottuvel Viswanathan, Beamon Agarwal, Aditi Shastri, Ioannis Mantzaris, Murali Janakiram, Noah Kornblum, Ira Braunschweig, Amit Verma, Yang Shi, John Reinus, Olga Derman

“…SOS is a rare complication of stem cell transplantation and has significant morbidity and mortality. We present three cases of SOS and highlight underlying risk factors for its development, such as impaired clearance of alkylating agents (especially melphalan) in patients with renal failure and prolonged infection. …”
Get full text

Acute Coronary Syndrome after 17 Years of Bare Metal Stent Implantation: “Very” Very Late Stent Thrombosis by Raghavendra Rao K, S. Reddy, J. R. Kashyap, K. Vikas, Hithesh Reddy, Vadivelu Ramalingam

“…Very late stent thrombosis (VLST) is a catastrophic and life-threatening complication after percutaneous coronary intervention which presents as an acute coronary syndrome with significantly high mortality and morbidity. VLST is a rare entity with drug-eluting stents and even rarer with bare metal stents. …”
Get full text

Invasive Microascus trigonosporus Species Complex Pulmonary Infection in a Lung Transplant Recipient by Kelly E. Schoeppler, Martin R. Zamora, Noelle M. Northcutt, Gerard R. Barber, Gayle O’Malley-Schroeder, Dennis M. Lyu

“…Because of the high incidence of morbidity and mortality associated with invasive fungal infections, antifungal prophylaxis is often used in solid organ transplant recipients. …”
Get full text

Pregnancy and Delivery in Ehlers-Danlos Syndrome (Hypermobility Type): Review of the Literature by Indranil Dutta, Helen Wilson, Odiri Oteri

“…Cesarean section was deemed the most appropriate delivery method in this patient due to the possible complications including risk of joint dislocation and pain morbidity. No obstetric complications were experienced, and good maternal and neonatal outcomes were achieved.…”
Get full text

Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease by Sundeep J. Punamiya, Deepak N. Amarapurkar

“…Liver cirrhosis is associated with higher morbidity and reduced survival with appearance of portal hypertension and resultant decompensation. …”
Get full text

Successful Treatment of Adenovirus Infection with Brincidofovir in an Immunocompromised Patient after Hematological Stem Cell Transplantation by T. Van Genechten, J. van Heerden, T. Bauters, C. Dhooge

“…Immunocompromised patients, including hematopoietic stem cell transplantation (HSCT), HIV, and malnourished patients, are at increased risk for viral infections with high incidences of morbidity and mortality. In HSCT patients, the infection risk is increased until immune reconstitution is re-established. …”
Get full text

Co-infection with hepatitis B and human immunodeficiency virus: epidemiology, pathogenesis, and treatment by Yaozu He, Weiyin Lin, Fei Gu, Xianglong Lan, Linghua Li, Haijuan Wang

“…One of the leading causes of mortality and morbidity in HIV-infected individualsis liver disease, despite the administration of antiretroviral therapy for HIV and HBV. …”
Get full text

Colposcopy: its importance for the prevention of cervical cancer by Dayamí Rodríguez Soto, Eneida Bravo Polanco

“…Cervical cancer, or carcinoma of the cervix, is a disease that has caused great impact in all social spheres, contributing to the high rates of morbidity and mortality throughout the world, including malignant neoplasms that develop in the lower fibromuscular portion of the uterus. …”
Get full text

Multidisciplinary Approach to Obesity by Berna Bulut &Ccedil;akmak, Asl&yacute;han D&ouml;nmez

“…Obesity is a world wide public health problem which increases morbidity and mortality. A multidiciplinary approach is increasingly becoming important for treatment of obesity. …”
Get full text

The role of NF-κB in diabetic cardiomyopathy by Huang-Jun Liu, Le-Kun Gui, Han Wei, Xing-Yu Zhou, Zhen-Lan Liu, Li-Jun Jin

“…Diabetic cardiomyopathy (DCM), a major risk factor contributing to diabetes-related morbidity and mortality, manifests as a pathophysiologic condition in humans independently of coronary artery disease or hypertension. …”
Get full text

Uncommon Presentations of Axillary Artery Aneurysm by Radhika Vidyasagar, Umesh Gheewala Satish, Jithin Sony, K S Vinay, N Muralikrishna, K R Amullya, Poornima Palaniswamy, Davu Narendra Babu

“…Because of the high incidence of symptoms and complications and the minimal morbidity associated with repair, routine operative repair should be performed.…”
Get full text

Osteoprotegerin in Cardiometabolic Disorders by C. Pérez de Ciriza, A. Lawrie, N. Varo

“…The association of OPG with diabetic complications (neuropathy, nephropathy, or retinopathy) as well as with atherosclerosis, coronary artery calcification, morbidity, and mortality is pointed out. Moreover, OPG modulation by different treatments is also established. …”
Get full text