Transforming Cardiovascular Risk Prediction: A Review of Machine Learning and Artificial Intelligence Innovations by Dimitrios-Ioannis Kasartzian, Thomas Tsiampalis

“…Cardiovascular diseases (CVDs) remain a leading cause of global mortality and morbidity. Traditional risk prediction models, while foundational, often fail to capture the multifaceted nature of risk factors or leverage the expanding pool of healthcare data. …”
Get full text

Importance of diet in children and adolescents with obesity and asthma by Monika Soczewka, Andrzej Kędzia, Bogda Skowrońska, Elżbieta Niechciał

“…Obesity is linked to a greater asthma morbidity, and it increases the risk of severity of the disease course. …”
Get full text

Genetic Polymorphisms: A Novel Perspective on Acute Pancreatitis by Yong Chen, Chao Lian Xie, Ran Hu, Cheng Yi Shen, Mei Zeng, Chang Qiang Wu, Tian Wu Chen, Chen Chen, Meng Yue Tang, Hua Dan Xue, Zheng Yu Jin, Xiao Ming Zhang

“…Acute pancreatitis (AP) is a complex disease that results in significant morbidity and mortality. For many decades, it has compelled researchers to explore the exact pathogenesis and the understanding of the pathogenesis of AP has progressed dramatically. …”
Get full text

Kaposi Varicelliform Eruption in a Patient with Pemphigus Vulgaris: A Case Report and Review of the Literature by Bibisha Baaniya, Sudha Agrawal

“…Immediate treatment with antivirals helps to prevent mortality and morbidities. Here, we report a case of a 67-year-old male who developed haemorrhagic crusted lesions on pre-existing pemphigus lesions during his hospital stay and obtained almost 90% resolution of cutaneous lesions of Pemphigus vulgaris as well as Kaposi varicelliform eruption within 2 weeks of acyclovir treatment along with the continuation of systemic steroids. …”
Get full text

Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge by Steven De Keukeleire, Daniëlle Borrey, Wim Decaluwe, Marijke Reynders

“…Necrotizing enterocolitis (NEC) continues to be a major cause of neonatal morbidity and mortality. We describe the added value of therapeutic drug monitoring by presenting the case of a preterm infant with severe NEC treated with meropenem. …”
Get full text

Non tuberculous Mycobacterial Surgical Site Infections after Laparoscopic Surgery: A Case Series of 37 Patients by Akshant Anil Pathak, Karan Kumar, Vaibhav Aggarwal, Vivek Agrawal

“…A high degree of clinical suspicion is warranted to limit morbidity.…”
Get full text

From Global Insights to National Impact: Advancing Cardio-Oncology in Iraq by Mustafa H. Ajlan, Hasan A. Farhan, Zainab A. Dakhil

“… Cancer remains a leading cause of mortality and morbidity worldwide. Advances in cancer therapies—including immunotherapies (e.g., checkpoint inhibitors, gene-targeted therapies), antibody-based cancer toxins, chemotherapy, radiotherapy, and surgery—have significantly improved survival rates 1,2. …”
Get full text

Accidental Ingestion of 35% Hydrogen Peroxide by Sean Pritchett, Daniel Green, Peter Rossos

“…Ingestion of hydrogen peroxide is not an uncommon source of poisoning, and results in morbidity through three main mechanisms: direct caustic injury, oxygen gas formation and lipid peroxidation. …”
Get full text

Pancreaticoduodenectomy as an option for treating a hemodynamically unstable traumatic pancreatic head injury with a pelvic bone fracture in Korea: a case report by Sung Yub Jeong, Yoonhyun Lee, Hojun Lee

“…Traumatic pancreatoduodenectomy (PD) has significant morbidity and appreciable mortality owing to complicating factors, associated injuries, and shock. …”
Get full text

Magnetic Foreign Body Ingestion in Children: The Attractive Hazards by Anna Lin, Lawrence Chi Ngong Chan, Kam Lun Ellis Hon, Siu Yan Bess Tsui, Kristine Kit Yi Pang, Hon Ming Cheung, Alexander K. C. Leung

“…However, on occasion, they can also be a rare cause of morbidity and even mortality, such as in the case of multiple magnetic foreign body ingestion, which can cause injury via magnetic attraction through bowel walls. …”
Get full text

Recent insights into the cellular mechanisms of acute pancreatitis by Laura I Cosen-Binker, Herbert Y Gaisano

“…Such localized events then progress to a systemic inflammatory response leading to multiorgan dysfunction syndrome with resulting high morbidity and mortality. The present review discusses some of the most recent insights into each of these cellular processes postulated to cause or propagate the process of acute pancreatitis, and also the role of alcohol and genetics.…”
Get full text

Pancreatic Pseudocyst with Splenic Artery Erosion, Retroperitoneal and Splenic Hematoma by Petre V. H. Botianu, Adrian S. Dobre, Ana-Maria V. Botianu, Danusia Onisor

“…The case shows that the pancreatic pseudocysts may present with acute hemorrhagic complications with life-endangering potential and significant postoperative morbidity.…”
Get full text

A Narrative Review of Existing Options for COVID-19-Specific Treatments by Wasey Ali Yadullahi Mir, Abdul Hasan Siddiqui, Gautam Valecha, Shawn Patel, Fatima Ayub, Riddhi Upadhyay, Sana Ahmed Alhajri, Suman Gaire, Dhan Bahadur Shrestha

“…The ongoing COVID-19 pandemic has affected morbidity and mortality tremendously. Even though multiple drugs are being used throughout the world since the advent of COVID-19, only limited treatment options are available for COVID-19. …”
Get full text

Foreign Body Aspiration of a Dental Bridge in the Left Main Stem Bronchus by Monay Mahmoud, Syed Imam, Hetalben Patel, Matthew King

“…Prompt diagnosis and intervention through foreign body retrieval are critical to prevent significant morbidity and mortality. Retrieval procedure is risky, and sudden decompensation of the patient can occur anytime. …”
Get full text

An Unexpected Presentation of Haemoperitoneum in a Pregnant Woman by Kaushalya Arulpragasam, Andrea Atkinson, Mathias Epee-Bekima

“…Corpus luteal cyst rupture is a common phenomenon but often not the cause of significant morbidity as it was in this case, especially in the absence of any associated risk factors.…”
Get full text

Cord Entanglement in Monoamniotic Twin Pregnancy: A Case Report and Review of the Literature by Ayşe Figen Türkçapar, Berna Seçkin, Ayla Sargın Oruç

“…Umbilical cord entanglements, twin-to-twin transfusion syndrome, congenital malformations, intrauterine growth restriction, and prematurity are responsible for the high perinatal morbidity and mortality. Cord entanglement can potentially compromise the cord blood flow and cause fetal demise. …”
Get full text

Therapeutic drug monitoring for triazoles: A needs assessment review and recommendations from a Canadian perspective by Michel Laverdiere, Eric J Bow, Coleman Rotstein, Julie Autmizguine, Raewyn Broady, Gary Garber, Shariq Haider, Trana Hussaini, Shahid Husain, Philippe Ovetchkine, Jack T Seki, Yves Théorêt

“…Invasive fungal infections cause significant morbidity and mortality in patients with concomitant underlying immunosuppressive diseases. …”
Get full text

Fulminant Mucormycosis Involving Paranasal Sinuses: A Rare Case Report by Komali Garlapati, Sunanda Chavva, Rahul Marshal Vaddeswarupu, Jyotsna Surampudi

“…Mucormycosis is an opportunistic fulminant fungal infection, which has the ability to cause significant morbidity and frequently mortality in the susceptible patient. …”
Get full text

Dyspnea due to Pulmonary Vessel Arteritis by Suzana M Gilmour, Giulio S Dominelli, Jonathon A Leipsic, Robert D Levy

“…The diagnosis of pulmonary arteritis can be challenging and the associated morbidity is serious without prompt, directed treatment. …”
Get full text

Upper Gastrointestinal Tract Crohn's Disease by Hugh J Freeman

“…Although upper gastrointestinal involvement is increasingly recognized as a significant cause of morbidity in Crohn's disease, the treatment options are limited , largely anecdotal and need to be the subject of detailed epidemiologic investigation and clinical trials.…”
Get full text