Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models by Linglin Tian, Huiyang Gao, Tian Yao, Tian Yao, Yuhao Chen, Linna Gao, Jingxiang Han, Lanqi Zhu, He Huang, He Huang, He Huang

“…BackgroundUlcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with increasing incidence worldwide. Growing evidence highlights the pivotal role of nicotinamide adenine dinucleotide (NAD+) metabolism in UC pathogenesis, prompting our investigation into the subtype-specific molecular underpinnings and diagnostic potential of NAD+ metabolism-related genes (NMRGs).MethodsTranscriptome data from UC patients and healthy controls were downloaded from the GEO database, specifically GSE75214 and GSE87466. …”
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Chemical Composition of Mexicali Propolis and Its Effect on Gastric Repair in an Indomethacin-Induced Gastric Injury Murine Model by Pilar Dominguez-Verano, Nadia Jacobo-Herrera, Andrés Castell-Rodríguez, Octavio Canales-Alvarez, Maria Margarita Canales-Martinez, Marco Aurelio Rodriguez-Monroy

“…Propolis is a resinous substance produced by bees that has several biomedical properties that could contribute to the repair process of the gastric mucosa, such as antioxidant, anti-inflammatory, healing, and gastroprotective properties. …”
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Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function. by Bo Ning Wang, Xin Zhuo Zhang, Jin Yi Wu, Zhao Yu Zhang, Pei Kun Cong, Wen Wen Zheng, Shao Rong Long, Ruo Dan Liu, Jing Cui, Zhong Quan Wang

“…<h4>Conclusions</h4>Vaccination of mice with rTsCTL elicited an obvious protective immunity against larval challenge, impeded larval invasion of gut mucosa, enhanced gut epithelial integrity and barrier function, reduced worm burdens; it also alleviated gut and muscle inflammation. …”
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Determination of Palatal Soft Tissue Thickness and Safe Zone for Palatal Soft Tissue Harvest Using CBCT: A Retrospective Study by Hanan Aldhanhani, Bhavna Jha Kukreja, Sesha Reddy, Jovita D’souza, Hossam Abdelmagyd

“…Our decision to conduct this study was motivated by the dearth of knowledge on geographical variations in the thickness of the palatal masticatory mucosa. The aim of the present study is to comprehensively analyze the palatal mucosal thickness and indicate the safety zone for palatal soft tissue harvesting using cone beam computed tomography (CBCT). …”
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The effect of antifungal oral gel and ozonated water on tensile and compressive strength of two types of denture base materials: in-vitro study by Noha T. Alloush, Eman M. Ibraheem, Wessam M. Dehis

“…Background/aim Debris accumulation beneath the dentures initiates countless difficulties such as inflamed oral mucosa and denture stomatitis. Denture stomatitis is a prevalent pathologic illness that is commonly linked to Candida albicans. …”
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Transformando el desinterés por la lectura en las aulas: Innovación educativa hacia el fomento del hábito lector by María Elsa Guamanshí Guamán, Diana Mireya Herrera Herrera

“… Al respecto, el propósito de este estudio implica el desarrollo de las estrategias pedagógicas innovadoras para convertir el desinterés por la lectura en un hábito de lectura significativo entre los estudiantes de noveno año de educación básica en el Centro Educativo Comunitario Intercultural Bilingüe Morona Santiago. Debe señalarse que esta investigación se realiza en una institución bilingüe e intercultural, lo que significa que los estudiantes y el maestro enfrentan barreras culturales, lingüísticas y económicas que reducen significativamente la cantidad de materiales de lectura pertinentes, y afecta negativamente a la motivación de los alumnos. …”
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Immunotherapy combined with chemotherapy without locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: two case reports and a literature review by Yingna Gao, Xiaoqiong Shi, Jianqiao He, Hui Yao, Guoning Yu, Lin Zhao, Yi Ma, Yi Ma, Hongliang Zheng, Minhui Zhu, Caiyun Zhang

“…Levels of plasma EBV DNA decreased and remained below the minimum detection level consistently after four or five cycles of treatment, with no obvious symptoms of neck muscle fibrosis, throat mucosa dryness, ear congestion, or nasal congestion.ConclusionOur findings suggested that chemotherapy combined with a PD-1 inhibitor without LRRT, followed by sequential immunotherapy as maintenance, can achieve good results in some dmNPC patients. …”
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Natural exposure to Chikungunya virus in golden-headed lion tamarin (Leontopithecus chrysomelas, Kuhl, 1820) from non-protected areas in southern Bahia, Brazil: Implications and si... by Sofía Bernal-Valle, María Angélica Monteiro de Mello Mares-Guia, Filipe Vieira Santos de Abreu, Fabrício Souza Campos, Cirilo Henrique de Oliveira, Antônio Victor Veloso Ramos, Reizane Pereira Lordelo, Kristel De Vleeschouwer, Leonardo de Carvalho Oliveira, Hllytchaikra Ferraz Fehlberg, Ana Maria Bispo Filippis, Bergmann Morais Ribeiro, Paulo Michel Roehe, Anaiá da Paixão Sevá, Danilo Simonini-Teixeira, George Rego Albuquerque

“…Surveys were conducted in three groups within cocoa agroforests (cabrucas) in Ilhéus, and four groups in anthropized forest and agroforestry fragments in Una, between 2021 and 2022. …”
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Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma by Simin Li, Yang Wang, Rui Sun, Debora Franceschi, Hongying Pan, Chenxuan Wei, Anthony Chukwunonso Ogbuehi, Bernd Lethaus, Vuk Savkovic, Sebastian Gaus, Rüdiger Zimmerer, Dirk Ziebolz, Gerhard Schmalz, Xiao Jiang

“…Single-cell pseudotime trajectories were constructed with MONOCLE (version 2.6.4). Cell-cell interactions were analyzed with CellChat R package. …”
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Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus... by Ling Pan, Qi Wang, Weikang Li, Xiaohui Dong, Shiwei Xie, Beiping Tan, Hongyu Liu, Yan Wang

“…Additionally, the artemisinin-treated groups exhibited improved intestinal digestibility and mucosa health, as evidenced by increased α-amylase, lipase and trypsin activities, along with enhancements in villus height, villus width, and muscle thickness (P < 0.05). …”
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Ilaser Submucous Destruction in the Treatment of Hemorrhoids by S. A. Frolov, D. V. Vyshegorodtsev, A. M. Kuzminov, Yu. L. Trubacheva, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. N. Ryndin, A. A. Anarbaeva

“…The proposed method applying a fiber laser with a diode pump with a wavelength of 1940 nm makes it possible to affect transdermally the internal hemorrhoidal node without damaging the mucosa of the anal canal. The absence of postoperative wounds in the anal canal leads to a decrease in pain syndrome, and by day 7 there are no clinical manifestations of hemorrhoids. …”
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Desregulación emocional en población con TDAH; una aproximación teórica/Emotional dysregulation in the population with ADHD. A Theoretical Approach by Alejandra Alpizar

“…Esta última puede ser verbal, motora y cognitiva, también emocional. Se expresa por la desregulación emocional y afecta la capacidad de autorregularse emocionalmente e inhibir las emociones. …”
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Electroacupuncture Regulates Disorders of Gut-Brain Interaction by Decreasing Corticotropin-Releasing Factor in a Rat Model of IBS by Ying Chen, Yan Zhao, Dan-ni Luo, Hui Zheng, Ying Li, Si-yuan Zhou

“…EA treatment can decrease the expression of hypothalamic CRF and CRF-R1, relieve anxiety and depression, meanwhile reduce the expression of CRF-R1 in the gastrointestinal mucosa, increase ZO-1 expression, and adjust tight junctions (TJs) to repair the intestinal mucosal barrier. …”
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Efficacy of Endoscopic Radiofrequency Ablation for Treatment of Reflux Hypersensitivity: A Study Based on Rome IV Criteria by Yuan-Xi Jiang, Zhi-Yu Dong, Jun-Wen Wang, Ying Chen, Hui-Hui Sun, Shu-Chang Xu

“…We also assessed positive cell density of transient receptor potential vanilloid type 1 receptor (TRPV1) and calcitonin gene-related peptide (CGRP), both of which are biomarkers of afferent fibers, in biopsies obtained from esophageal mucosa 0.5 cm-1 cm above the Z line. These scales will be administered at baseline, 3-month follow-up, 6-month follow-up, and 12-month follow-up. …”
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Increased serum ferritin is associated with severity of orbital disease in COVID-19–associated rhino-orbito-cerebral mucormycosis: A quantitative analysis by Shashi Tanwar, Nibha Mishra, Prachi Sharma, Apjit Kaur

“…Based on the classification proposed by Honavar, the study patients were classified into four stages: Stage 1: involvement of the nasal mucosa (n = 11), Stage 2: involvement of paranasal sinuses (n = 14), Stage 3: involvement of the orbit (n = 37), Stage 4: involvement of the central nervous system (n = 38). …”
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Enteric-Coated Aspirin Induces Small Intestinal Injury via the Nrf2/Gpx4 Pathway: A Promising Model for Chronic Enteropathy by Zhang M, Xia S, Feng L, Han X, Zhang Y, Huang Y, Liu Y, Zhao K, Guan J, Tian D, Liao J, Yu Y

“…Aspirin led to a shortened small intestine, macroscopic and microscopic damage to the intestinal mucosa, and local inflammation. Aspirin disrupted the intestinal barriers and increased the permeability of the small intestine. …”
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Clinical Activity of Behcet&rsquo;s Disease Associated with SARS-CoV-2 and Herpes Simplex Virus: Insights from Three Case Reports by Bakti FU, Sufiawati I

“…Intraoral examination showed ulcerative, erosive, and white plaque lesions throughout the oral mucosa. The first patient was confirmed to have COVID-19 by the SARS-CoV-2 RNA test. …”
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Profil Pasien Rinosinusitis Kronik di Poliklinik THT-KL RSUP DR.M.Djamil Padang by Hesty Trihastuti, Bestari Jaka Budiman, Edison

“…<br />Kata kunci: rinosinusitis kronik, pemeriksaan rinoskopi anterior, pemeriksaan nasoendoskopi</p><p> </p><p>Abstract<br />Chronic rhinosinusitis is a common chronic inflammation of the nose and paranasal sinuses mucosa, but there  is no data about profile of chronic rhinosinusitis patients at ENT clinic Dr.M.Djamil general hospital Padang. …”
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EVALUACIÓN DEL EFECTO DE LA SUPLEMENTACIÓN DE LEVADURAS SOBRE LA MORFOMETRÍA DE VELLOSIDADES INTESTINALES Y PRODUCTOS DE LA MICROFLORA EN POLLOS by N. Lópes, G. Afanador, CJ Ariza

“…Los efectos tróficos positivos sobre la mucosa digestiva asociados al uso de levaduras en la alimentación de pollos de engorde, observados en esta investigación, confieren a estas un gran potencial nutricional y sugieren posteriores estudios que abarquen el ciclo completo de producción, involucrando otros factores relacionados con la capacidad de absorción de nutrientes…”
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Brucella suis ΔmapB outer membrane vesicles as an acellular vaccine against systemic and mucosal B. suis infection by Florencia Muñoz González, Florencia Muñoz González, Magali G. Bialer, Maria L. Cerutti, Silvia M. Estein, Lila Y. Ramis, Pablo C. Baldi, Pablo C. Baldi, Ángeles Zorreguieta, Ángeles Zorreguieta, Mariana C. Ferrero, Mariana C. Ferrero

“…Currently, there are no available human or porcine vaccines to protect against B. suis infection, which is primarily acquired through the mucosa. We recently described B. suis MapB, the homologous protein of TamB, the inner membrane component of the TAM system. …”
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