Polydatin protects against DSS-induced ulcerative colitis via Nrf2/Slc7a11/Gpx4-dependent inhibition of ferroptosis signalling activation by Shimin Zheng, Jianbin Yin, Bingbing Wang, Qiujuan Ye, Jialuo Huang, Xinzhi Liang, Junfeng Wu, Hui Yue, Ting Zhang

“…Ferroptosis-related proteins Slc7a11, Nrf2 and Gpx4 levels were measured by western blot, immunohistochemical and immunofluorescence staining.ResultsPD mitigated the DSS-induced increases in pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β), alleviated colon length shortening, reduced morphological damage to the intestinal mucosa, and preserved tight junction proteins (TJ) occludin and Zonula occludens-1 (ZO-1) in both caco-2 cells and murine models of colitis. …”
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ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis by Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe

“…Finally, analysis of normal colorectal mucosa demonstrated that the observed promoter hypermethylation was cancer-specific. …”
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INCLUSIÓN DE HARINAS DE FOLLAJES ARBÓREOS Y ARBUSTIVOS TROPICALES (Morus alba, Erythrina poeppigiana, Tithonia diversifolia EHibiscus rosa-sinensis) EN LA ALIMENTACIÓN DE CUYES (Ca... by G. A. Meza, N. J. Loor, A. R. Sánchez, J. H. Avellaneda, C. J. Meza, D. F. Vera, M. G. Cabanilla, G. A. Liuba, J. S. Meza, F. F. Meza, M. A. Ramírez, O. F. Moncayo, D. L. Cadena, R. O. Villamar, E. Díaz, L. M. Rizzo, J. M. Rodríguez, F. X. López

“…La investigación se ejecutó en la Finca Experimental “La María” propiedad de la Univer-sidad Técnica Estatal de Quevedo (UTEQ) localizada en el km 71/2de la vía Quevedo-Mocache; Provincia de Los Ríos cuya ubicación geográfica de 1º 6’ 23” de latitud sury 79º 29’ 12” de longitud oeste y a una altura de 73 m.s.n.m. …”
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Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation by Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang

“…Therefore, we conducted a detailed study of osteoclasts at the single cell level, aiming to find new OS therapeutic targets to prevent tumor progression and local spread.MethodsWe analyzed the single-cell sequencing data of OS patients and usedMonocle2, Cytotrace, and Slingshot software to analyze the pseudo-sequential trajectory during OS progression. …”
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Time-dependent Acceleration and Escape of Charged Particles at Traveling Shocks in the Near-Sun Environment by Thomas M. Do, Federico Fraschetti, Jozsef Kota, Joe Giacalone, Christina M. S. Cohen, David J. McComas

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Nutritional Value and Consumer Acceptance of New Cereal Bars Offered to Children by Białek Małgorzata, Rutkowska Jarosława, Radomska Justyna

“…The content of CN52, CN54, CN50 and CN46 triacylglycerols (TAGs) (about 49 g/100 g TAG) was due to both milk and cocoa fat. Storage of bars did not influence their content of oxidation and hydrolysis products, resulting from a substantial content of total phenolics (TPC) (53.64 mg GAE/100 mL of extract) and DPPH scavenging activity at the level of 24%. …”
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Sweets and other sugary foods – a scoping review for Nordic Nutrition Recommendations 2023 by Henna Vepsäläinen, Emily Sonestedt

“…Results: Most of the papers included from the search focused on chocolate or cocoa, which are rich in flavonoids. We found some evidence linking chocolate consumption with lower blood pressure, lower risk of type 2 diabetes, and improved insulin markers, but the evidence was ranked low or very low. …”
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Distribution of humic substances in sieved aggregates of soil under contrasting land use by Bassey Udom, Achimota Dickson, Gogo Arthur, Miebaka Ikiriko, Babatunde Nuga

“…Humified carbon (HC), humified acid carbon (HAC), and aggregate-associated fulvic acid carbon (FAC) in forest soils, cocoa plantations, five-year fallow, and five-year continuous cultivated soils were studied. …”
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El aprendizaje-servicio en edad escolar en el área de Educación Física: una revisión sistemática by Carlos Sánchez, Manuel-Jacob Sierra Díaz, Sixto Gonzalez- Villora

“…Entre los beneficios: mayor adherencia a la actividad física, la mejora de hábitos saludables y habilidades motoras. El aprendizaje-servicio demostró ser eficaz en el desarrollo de competencias sociales y cívicas. …”
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Forensic Dermatology Expert Analytical Report: A New Frontier of Forensic Medicine by Philip R. Cohen, Lerah Sutton

“…Dermatologists are experts in evaluating the skin, mucosa, hair, and nails. It is anticipated that the demand for forensic dermatology will increase as individuals who currently evaluate crime scenes become aware of the potential benefit of consulting a forensic dermatologist. …”
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lncRNA FR215775 Regulates Th2 Differentiation in Murine Allergic Rhinitis by Yue Ma, Le Shi, Keqing Zhao, Chunquan Zheng

“…Meanwhile, the eosinophilia inflammation, goblet cell hyperplasia, and mast cell inflammation in the nasal mucosa all decreased, which indicated attenuated allergic inflammation in the lncRNA FR215775-silencing AR group. …”
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Síndrome de Millard-Gubler de etiología traumática: caso clínico by Alex Mauricio Altamirano, Macarena Brigitte Martínez Basantes, Evelyn Carolina Guananga Chico, Maybrith Fernanda Cárdenas Balarezo

“…Se instauraron medidas de soporte y administración de glucocorticoides, con lo cual hubo una disminución de la debilidad muscular en la extremidad y la cara, con persistencia de la parálisis ocular motora durante la fase aguda. Discusión: los síndromes alternos de tallo cerebral constituyen un reto diagnóstico en la práctica diaria, dentro de las causas más comunes se ha observado el ataque cerebrovascular, los tumores de tallo cerebral y la desmielinización, pero existen escasos reportes sobre la etiología traumática y su evolución clínica. …”
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ATIVIDADE FÍSICA NO CONTEXTO DOS DESLOCAMENTOS: REVISÃO SISTEMÁTICA DOS ESTUDOS EPIDEMIOLÓGICOS REALIZADOS NO BRASIL by Carla Menêses Santos, Jessyka Mary Vasconcelos Barbosa, Luanna Alexandre Cheng, Rildo de S. Wanderley júnior, Mauro Virgilio Gomes de Barros

“…Para o desenvolvimento deste estudo foi realizada uma busca pelos manuscritos indexados nas bases de dados Medline/PubMed e Lilacs utilizando, em português e inglês, os seguintes descritores/termos: “atividade física”, “exercício”, “aptidão física”, “sedentarismo”, “inatividade”, “atividade motora”, “transportes”, “deslocamento residência-trabalho”, “caminhada”, “ciclismo”, “viagem”, “locomoção”, “Brasil”, “brasileiros”. …”
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Guidance for otolaryngology health care workers performing aerosol generating medical procedures during the COVID-19 pandemic by Marc J. W. Lammers, Jane Lea, Brian D. Westerberg

“…Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for Coronavirus disease 2019 (COVID-19) has a predilection for infecting the mucosa of the upper and lower airways. Otolaryngologists and supporting health care workers (HCWs) are particularly at high risk of becoming infected while treating patients as many in-office procedures and surgeries are Aerosol Generating Medical Procedures (AGMP). …”
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Prevalencia y diagnóstico de la enfermedad celíaca en niños by Mayumi Hernández Díaz, Armando Fermín Álvarez Corcuera, Sergio Luis González López

“…<strong>Fundamento:</strong> la enfermedad celíaca es una afección autoinmune, sistémica, crónica, inducida por las proteínas del gluten que provocan un daño de la mucosa intestinal en los individuos genéticamente predispuestos, esta patología presenta una alta prevalencia en la edad pediátrica. …”
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Contusión medular en ratas tratadas con hipotermia sistémica. Expresión de proteínas inducibles por frío experimental by Aníbal José Sarotto, María Agustina Toscanini, Daniela Contartese, Verónica B. Dorfman, Ronan Nakamura, Micaela Besse, Ignacio M. Larráyoz, Alfredo Martínez, Elena De Matteo, Manuel Rey-Funes, César Fabián Loidl

“…Introducción: La lesión traumática de la médula espinal es la principal causa mundial de discapacidad motora y una prioridad para la OMS. El objetivo de esta investigación fue estudiar el efecto de la hipotermia terapéutica tras una contusión medular. …”
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Rabies-preventive health program for mothers in maternal and child health centers: quasi experimental study by Samia Ibrahim Mabrouk Baraka, Rania Abd Elmohsen Abo El Nour, M. A. Abdelzaher, Eman Mahmoud Seif El–Nasr

“…Abstract Background Rabies spreads to people and animals via saliva, usually through bites, scratches, or direct contact with mucosa (e.g. eyes, mouth, or open wounds). Rabies remains a major public health problem in Egypt, with an estimated 60 people dying annually from the disease. …”
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The Association of HOTAIR with the Diagnosis and Prognosis of Gastric Cancer and Its Effect on the Proliferation of Gastric Cancer Cells by Zhiying Xu, Hui Chen, Bin Yang, Xiangfeng Liu, Xiaoli Zhou, Hongfang Kong

“…The expression levels of HOTAIR in 54 GC tissues and their matched adjacent nontumor tissues from GC patients and 24 normal mucosa or those with minimal gastritis as healthy controls were determined by qRT-PCR. …”
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Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis by Mengmeng Zhang, Hong Lv, Xiaoyin Bai, Gechong Ruan, Qing Li, Kai Lin, Hong Yang, Jiaming Qian

“…Methods RNA-sequencing of colonic mucosa from adult- and elderly-onset UC patients was performed. …”
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Relación de los genotipos CagA/VacA del Helicobacter pylori con lesiones precursoras de cáncer gástrico by Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Palomino Besada, Osvaldo Miranda Gómez, Danay Días Morejón

“…Los individuos con cepas CagA y VacA s1m1 desarrollan lesiones de la mucosa más graves. El sistema Operative Link on Gastritis Assessment permite determinar el riesgo de cáncer y define la atrofia como la lesión típica de progresión de la gastritis crónica. …”
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