Serum Growth Differentiation Factor 15 is Negatively Associated with Leukocyte Telomere Length by Jie Yu, Yiwen Liu, Huabing Zhang, Fan Ping, Wei Li, Lingling Xu, Yuxiu Li

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Biogeographic Insights Into the Late Miocene Diversification of the Giant Deep‐Ocean Amphipod Eurythenes by Carolina E. González, Johanna N. J. Weston, Reinaldo Rivera, Marcelo Oliva, Rubén Escribano, Osvaldo Ulloa

“…These large‐bodied scavengers play key roles in benthic communities. We constructed a time‐calibrated phylogeny using two mitochondrial DNA genes by analyzing publicly available data on 14 species of Eurythenes across a global depth range from 839 to 8081 m. …”
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α-Bisabolol alleviates diesel exhaust particle-induced lung injury and mitochondrial dysfunction by regulating inflammatory, oxidative stress, and apoptotic biomarkers through the... by Sumaya Beegam, Nur Elena Zaaba, Ozaz Elzaki, Abderrahim Nemmar

“…The activities of mitochondrial complexes I, II, III, and IV were markedly increased in the lungs of mice exposed to DEPs, and these effects were significantly reduced in the BIS-treated group. …”
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From Ca2+ dysregulation to heart failure: β-adrenoceptor activation by RKIP postpones molecular damages and subsequent cardiac dysfunction in mice carrying mutant PLNR9C by correct... by Theresa Brand, Bettina Tanitha Baumgarten, Sabrina Denzinger, Yvonne Reinders, Miriam Kleindl, Constanze Schanbacher, Florian Funk, Nilgün Gedik, Mahmood Jabbasseh, Petra Kleinbongard, Jan Dudek, Julia Szendroedi, Elen Tolstik, Kai Schuh, Martina Krüger, Dobromir Dobrev, Friederike Cuello, Albert Sickmann, Joachim P. Schmitt, Kristina Lorenz

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A pharmacoinformatic approach for studying Atractylodes Lancea DC’s anticancer potential and control ROS-mediated apoptosis against prostate cancer cells by Chi-Hoon Ahn, Ji Soo Myong, Kazi Rejvee Ahmed, Md Ataur Rahman, Md. Maharub Hossain Fahim, Min Choi, Muntajin Rahman, Jinwon Choi, Kiryang Kim, Seungjoon Moon, Seungjoon Moon, Mohammed Dalli, Mohammed Dalli, Rony Abdi Syahputra, Sang-Won Shin, Abdel Halim Harrath, Moon Nyeo Park, Bonglee Kim, Hwa-Seung Yoo

“…Cell viability was assessed using the EZ-Cytotoxic kit, while colony formation assays and TUNEL staining were used to meas-ure proliferation and apoptosis, respectively. …”
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Genetic history of the Koryaks and Evens of the Magadan region based on Y chromosome polymorphism data by B. A. Malyarchuk, M. V. Derenko

“…In order to clarify the history of gene pool formation of the indigenous populations of the Northern Priokhotye (the northern coast of the Sea of Okhotsk), Y-chromosome polymorphisms were studied in the Koryaks and Evens living in the Magadan region. …”
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Connections Across Open Water: A Bi‐Organelle, Genomics‐Scale Assessment of Atlantic‐Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark (Isurus oxyrinchus) by Andrea M. Bernard, Marissa R. Mehlrose, Kimberly A. Finnegan, Bradley M. Wetherbee, Mahmood S. Shivji

“…Genomic‐scale population assessments for this apex predator species have not been previously available to inform management planning; thus, we investigated the population genetics of mako sharks across the Atlantic using a bi‐organelle genomics approach. …”
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Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2 by Karen J. Juárez-Navarro, Eduardo Padilla-Camberos, Néstor Fabián Díaz, Ariel Miranda-Altamirano, N. Emmanuel Díaz-Martínez

“…Mesenchymal stem cells (MSCs), defined as plastic adherent cells with multipotent differentiation capacity in vitro, are an emerging and valuable tool to treat a plethora of diseases due to their therapeutic mechanisms such as their paracrine activity, mitochondrial and organelle transfer, and transfer of therapeutic molecules via exosomes. …”
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Phylogeographic analyses reveal recent dispersal and multiple Wolbachia infections of the bright-eyed ringlet Erebia oeme within the European mountain systems by Valentine Mewis, Martin Wendt, Thomas Schmitt

“…We analysed two mitochondrial (COI, Cytb) and eight nuclear markers as well as the Wolbachia surface protein-coding gene (WSP). …”
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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

“…Abstract Chronic innate immune activation in the central nervous system (CNS) significantly contributes to neurodegeneration in progressive multiple sclerosis (MS). Using multiple experimental autoimmune encephalomyelitis (EAE) models, we discovered that NLRX1 protects neurons in the anterior visual pathway from inflammatory neurodegeneration. …”
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Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations by Rebecca T. Miceli, Tzu‐Yi Chen, Yohei Nose, Swapnil Tichkule, Briana Brown, John F. Fullard, Marilyn D. Saulsbury, Simon O. Heyliger, Sacha Gnjatic, Natasha Kyprianou, Carlos Cordon‐Cardo, Susmita Sahoo, Emanuela Taioli, Panos Roussos, Gustavo Stolovitzky, Edgar Gonzalez‐Kozlova, Navneet Dogra

“…For the inclusion of different particles discussed in this article, we use the terms large/small EVs, non‐vesicular extracellular particles (NVEPs), EPs and EVPs as defined in MISEV guidelines by the International Society of Extracellular Vesicles (ISEV).…”
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The problems of genetic support of dividing the black kite (Milvus migrans) into subspecies by N. G. Andreyenkova, I. J. Starikov, M. Wink, I. V. Karyakin, O. V. Andreyenkov, I. F. Zhimulev

“…On the grounds of earlier studies of mitochondrial and nuclear genes of this species, we check whether there is a genetic support for separation of the black kite subspecies. …”
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MitoSeg: Mitochondria segmentation tool by Faris Serdar Taşel, Efe Çi̇ftci̇

“…In this paper, we present a software solution for mitochondrial segmentation using an automatic validation scheme based on the general physical properties of mitochondria, highlighting boundaries in electron microscopy tomography images and generating corresponding 3D meshes. …”
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NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy by Nik M. Mustapha, Joanna M. Tarr, Eva M. Kohner, Rakesh Chibber

“…Objectives. Using apocynin (inhibitor of NADPH oxidase), and Mitoquinol 10 nitrate (MitoQ; mitochondrial-targeted antioxidant), we addressed the importance of mitochondria versus NADPH oxidase-derived ROS in glucose-induced apoptosis of pericytes. …”
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Genetic studies of normal tension glaucoma by D.Yu. Plotnikov, E.V. Valeeva

“…</p> <p> <b>Keywords: </b>glaucoma, normal tension glaucoma, genes, genetic studies, polymorphisms. </p> <p> <b>For citation:</b> Plotnikov D.Yu., Valeeva E.V. …”
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Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells by Ambrož Martin, Šmatová Markéta, Šadibolová Michaela, Pospíšilová Eva, Hadravská Pavlína, Kašparová Michaela, Skarková Veronika Hanušová, Králová Věra, Skálová Lenka

“…Based on these results, CAO seems to have the potential for combination therapy of colon cancers and deserves further study.…”
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DNA barcoding reveals an unexpected distribution of two Megaleporinus species in the La Plata Basin system by Florencia Paola Coronel, Gisela Loretán, Gisela Loretán, Gisela Loretán, Sebastián Sanchez, Sebastián Sanchez, Natalia Silva, Natalia Silva, Gualberto Pacheco-Sierra, Florencia Brancolini, Florencia Brancolini, Danilo Aichino, Facundo Vargas, Pablo Scarabotti, Pablo Scarabotti, Luis Espínola, Luis Espínola, Carla Simone Pavanelli, Eva Carolina Rueda, Eva Carolina Rueda

“…Despite various approaches, including cytogenetics, molecular data, and morphological analysis, the taxonomic classification of the boga fish remains debated among researchers, resulting in discrepancies in the literature.MethodsThis study aimed to assess the diversity of specimens captured in the La Plata River Basin, initially classified as Megaleporinus obtusidens by fishers, using DNA barcoding. The mitochondrial COI marker was employed to explore species assignment and genetic diversity in Megaleporinus, a genus with high commercial exploitation in the southern area of the La Plata Basin.ResultsOur findings indicate that some boga samples, previously identified as M. obtusidens, are actually M. piavussu. …”
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High quality genome assembly and annotation (v1) of the eukaryotic terrestrial microalga Coccomyxa viridis SAG 216-4 by Kraege, Anton, Chavarro-Carrero, Edgar A., Guiglielmoni, Nadège, Schnell, Eva, Kirangwa, Joseph, Heilmann-Heimbach, Stefanie, Becker, Kerstin, Köhrer, Karl, Schiffer, Philipp, Thomma, Bart P. H. J., Rovenich, Hanna

“…While 19 scaffolds represent full-length nuclear chromosomes, two additional scaffolds represent the mitochondrial and plastid genomes. Transcriptome-guided gene annotation resulted in the identification of 13,557 protein-coding genes, of which 68% have annotated PFAM domains and 962 are predicted to be secreted.…”
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Renoprotective effects of coenzyme Q10 supplementation in patients with chronic kidney disease: a protocol for a systematic review by Hisashi Noma, Takeshi Hasegawa, Hiroki Nishiwaki, Erika Ota, Taihei Suzuki, Yoshitaka Watanabe, Yoshifusa Abe

“…For outcomes measured using continuous scales of measurement, we will adopt standardised mean differences as the effect measures. …”
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Cell–cell heterogeneity in phosphoenolpyruvate carboxylase biases early cell fate priming in Dictyostelium discoideum by Kenichi Abe, Hidenori Hashimura, Haruka Hiraoka, Shoko Fujishiro, Narufumi Kameya, Kazuteru Taoka, Satoshi Kuwana, Masashi Fukuzawa, Satoshi Sawai, Satoshi Sawai, Satoshi Sawai

“…Furthermore, the PEPC null mutant had high ATP levels and low mitochondrial membrane potential. Our results suggest the importance of cell–cell heterogeneity in the levels of metabolic enzymes during early cell fate priming.…”
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