Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro by Sun yingfei, Yang feng, Ma haoning

“…In recent years, extreme high-temperature weather events have occurred frequently in the world, which directly led to a significant increase in heatstroke. …”
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Resolving Rapid Radiation of Voles and Lemmings (Arvicolinae: Cricetinae, Rodentia) with QuaddRAD Sequencing and Transcriptome Analysis by Natalia Abramson, Elizaveta Skalon, Olga Bondareva, Semen Bodrov, Tatyana Petrova, Ivan Dvoyashov

“…Voles and lemmings (subfamily Arvicolinae) remain some of the most difficult groups for disentangling phylogenetic relations owing to recent and very fast explosive radiation. The rapid radiation events are challenging for phylogenetic analysis and produce bushes of various shapes that are impossible to resolve with a straightforward approach using individual loci. …”
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The neurotoxicity of iodoacetic acid, a byproduct of drinking water disinfection by Xu Wang, Xu Wang, Xu Wang, Chunshu Rong, Ping Niu, Wei Leng, Gaihua Wang, Ziqiao He, Xin Qi, Dexi Zhao, Dexi Zhao, Jinhua Li

“…In neurological manifestations, IAA can lead to neurotransmitter disorders, neurodevelopment dysfunction, and even neurodegenerative diseases. Taken together, our review provides insights into the mechanisms of IAA neurotoxicity that will contribute to future studies of IAA neurotoxicity and its protective strategies.…”
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Bcl-2 and Bcl-xL in Diabetes: Contributions to Endocrine Pancreas Viability and Function by Atenea A. Perez-Serna, Daniel Guzman-Llorens, Reinaldo S. Dos Santos, Laura Marroqui

“…Diabetes is a chronic metabolic disorder whose prevalence increases every year, affecting more than 530 million adults worldwide. …”
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Combining and congruence evaluation of phylogenetic signals from different genes based on geometric approach by V. M. Efimov, V. Yu. Kovaleva, Yu. N. Litvinov

“…Several variability directions reflecting evolutionary events of different scale are visualized in a joint genetic space. …”
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Clonorchis sinensis and Echinostoma hortense detected by endoscopy and molecular characterization: two case reports and update on diagnosis by Lijia Wen, Benhe Wang, Hui Zhang

“…C. sinensis stands as the primary parasite underlying cholangitis, cholelithiasis, and even cholangiocarcinoma, whereas E. Hortense parasitizes the duodenum. …”
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Investigation of genetic structure of various cat breeds by using d-loop polimorphism in turkey by Elif Yılmaz Şahin, Vahdettin Altunok, Ercan Kurar

“…<p> <b>Results:</b> Each of every Van cats were evaluated in their groups according to one eye or double eye and statistical differentiation was found (P<0.022) between groups. …”
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Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases? by Stefania Gonfloni, Emiliano Maiani, Claudia Di Bartolomeo, Marc Diederich, Gianni Cesareni

“…Herein, we review some reports on c-Abl function in neuronal cells and we propose that modulation of different aspects of c-Abl signaling may contribute to mediate the molecular events at the interface between stress signaling, metabolic regulation, and DNA damage. …”
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Earthworm (Oligochaeta, Lumbricidae) intraspecific genetic variation and polyploidy by S. V. Shekhovtsov, Ye. A. Derzhinsky, E. V. Golovanova

“…The key to such a complex picture is probably the plasticity of reproductive modes in earthworms, which encompass diverse modes of sexual and asexual reproduction; also, it has been demonstrated that even high-ploidy forms can retain amphimixis.…”
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Neuroprotective and Anti-inflammatory Effects of Pioglitazone on Traumatic Brain Injury by Mohammad Yassin Zamanian, Niloofar Taheri, Maria Jade Catalan Opulencia, Dmitry Olegovich Bokov, Sharif Y. Abdullaev, Mohammadreza Gholamrezapour, Mahsa Heidari, Gholamreza Bazmandegan

“…Patients of TBI continue to suffer from brain injury through an intricate flow of primary and secondary injury events. However, when treatment is provided in a timely manner, there is a significant window of opportunity to avoid a few of the serious effects. …”
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GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

“…This genome could be called a strategic genome used only for beginning of a new organism. Every cell of organism has the same genome, but active are only particular program genes, specific for the cell destination; this is a tactic genome. …”
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Preamplification Procedure for the Analysis of Ancient DNA Samples by Stefania Del Gaudio, Alessandra Cirillo, Giovanni Di Bernardo, Umberto Galderisi, Theodoros Thanassoulas, Theodoros Pitsios, Marilena Cipollaro

“…A comparison between results obtained from nonpreamplified and preamplified samples is reported. Our data, even if preliminary, show that the TaqMan PreAmp procedure may improve the sensitivity of qPCR analysis.…”
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Fumonisin B1 neurotoxicity: Preclinical evidence, biochemical mechanisms and therapeutic strategies by Blessing A. Obafemi, Isaac A. Adedara, Cássia Pereira Delgado, Olabisi T. Obafemi, Michael Aschner, Joao B.T. Rocha

“…Both in vitro and in vivo studies have demonstrated that alteration in sphingolipid metabolism is a major event in FB-induced neurotoxicity. Studies have also shown that neurotoxicity due to FB1 involves dysregulation of several biochemical events in the brain, such as induction of oxidative stress and inflammation, mitochondrial dysfunction and associated programmed cell death, inhibition of acetylcholinesterase and alteration of neurotransmitter levels, decreased activity of Na+K+ ATPase, as well as disruption of blood-brain barrier. …”
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Comparative organelle genomics in Daphniphyllaceae reveal phylogenetic position and organelle structure evolution by Rongxiang Zhang, Ying Liu, Shuwen Liu, Yuemei Zhao, Niyan Xiang, Xiaoman Gao, Tao Yuan

“…We identified several unidirectional protein-coding gene transfer events from the plastome to the mitogenome based on homology analysis, but no transfer events occurred from the mitogenome to the plastome. …”
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Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

“…Beta cell death is the final event in a series of mechanisms that, up to date, have not been entirely clarified; it represents the pathophysiological mechanism in the natural history of diabetes mellitus. …”
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A Drosophila melanogaster mitotype may have an adaptive meaning by D. V. Petrovskii, L. P. Zakharenko

“…We assume that individuals with widespread clade М(III) may have adaptive advantages compared to other mitotypes due to their greater locomotor activity even with the same energy expenditure. Further studies are required, for mitotypes are polymorphic for single nucleotide polymorphism not only between but also within the clades.…”
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Efficiency of the Stool-PCR Test Targeting NADH Dehydrogenase (Nad) Subunits for Detection of Opisthorchis viverrini Eggs by Wansika Phadungsil, Supaporn Pumpa, Kridsada Sirisabhabhorn, Amornrat Geadkaew-Krenc, Rudi Grams, Mathirut Mungthin, Toon Ruang-Areerate, Poom Adisakwattana, Nipawan Labbunruang, Pongsakorn Martviset

“…Our study established that OvNad subunits, especially OvNad5, are the potent candidates for PCR amplification of stool containing Ov-eggs with high confidential sensitivity, specificity, PPV, and NPV even in the light infection that would be a benefit for developing as a routine diagnosis of O. viverrini infection.…”
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lnc-MRGPRF-6:1 Promotes ox-LDL-Induced Macrophage Ferroptosis via Suppressing GPX4 by Zhihuan You, Xiaotian Ye, Meihua Jiang, Ning Gu, Caihong Liang

“…These indicated that lnc-MRGPRF-6:1 may suppress GPX4 to induce macrophage ferroptosis. Eventually, lnc-MRGPRF-6:1 was highly expressed in the monocyte-derived macrophages of CAD patients and was negatively correlated with the expression of GPX4. …”
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Diversification outbreaks and dynamics of Asian leaf-litter frogs, genus Leptobrachella (Anura, Megophryidae), with the description of a new species from Guizhou Province, China by Tao Luo, Zi-Fa Zhao, Zhong-Lian Wang, Chang-Ting Lan, Ming-Yuan Xiao, Huai-Qing Deng, Ning Xiao, Jiang Zhou

“…The uplift of the Qinghai-Tibet Plateau and the Indochina extrusion are two of the most prominent consequences of the India–Asia collision. These two geologic events greatly altered topography and drainage patterns that, in turn, affected the regional climate, the landscape and the evolution of biodiversity. …”
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Genetic variability and population structure analysis of Protostrongylus oryctolagi (Nematoda: Protostrongylidae) in Lepus europaeus from Central and Northern Italy. by Ilaria Guarniero, Laura Stancampiano, Rafaella Franch, Elisa Armaroli, Fabio Macchioni, Enrico Negrisolo

“…Lineage A showed a preference for Central Italy (Tuscany) even if it was sporadically found also in northern territories (Emilia-Romagna), while B-haplotypes were present exclusively in Emilia-Romagna. …”
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