Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

“…The necrosis of pancreatic acinar cells is a key molecular event in the progression of acute pancreatitis (AP), with disturbances in mitochondrial energy metabolism considered to be a direct causative factor of acinar cell necrosis. …”
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The problems of genetic support of dividing the black kite (Milvus migrans) into subspecies by N. G. Andreyenkova, I. J. Starikov, M. Wink, I. V. Karyakin, O. V. Andreyenkov, I. F. Zhimulev

“…Furthermore, the mitochondrial haplotype difference suggests that the African yellow-billed kite, including M. m. aegyptius and M. m. parasitus, should be a separate species as already proposed, or even two separate species.…”
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Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2 by Karen J. Juárez-Navarro, Eduardo Padilla-Camberos, Néstor Fabián Díaz, Ariel Miranda-Altamirano, N. Emmanuel Díaz-Martínez

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Heterothallism and potential hybridization events inferred for twenty-two yellow morel species by Xi-Hui Du, Dongmei Wu, Heng Kang, Hanchen Wang, Nan Xu, Tingting Li, Keliang Chen

“…Recently, potential hybridization events and MAT genes were separately found in the Elata Clade of Morchella. …”
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Cuproptosis Cell Death Molecular Events and Pathways to Liver Disease by Mao Y, Chen H, Zhu W, Ni S, Luo S, Tang S, Chen Z, Wang Q, Xu J, Tu Q, Chen H, Zhu L

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Genetic history of the Koryaks and Evens of the Magadan region based on Y chromosome polymorphism data by B. A. Malyarchuk, M. V. Derenko

“…High frequency of haplogroup C-B80, typical of other Tungus-Manchurian peoples, is characteristic of the Evens of the Magadan region. The shared components of the gene pools of the Koryaks and Evens are haplogroups R-M17 and I-P37.2 inherited as a result of admixture with Eastern Europeans (mainly Russians). …”
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MeHg Causes Ultrastructural Changes in Mitochondria and Autophagy in the Spinal Cord Cells of Chicken Embryo by Fabiana F. Ferreira, Evelise M. Nazari, Yara M. R. Müller

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The mitochondria as an emerging target of self-renewal in T-cell acute lymphoblastic leukemia by Majd A. Al-Hamaly, Evelyn Winter, Jessica S. Blackburn

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Multi-omics analysis in inclusion body myositis identifies mir-16 responsible for HLA overexpression by Daphne Wijnbergen, Mridul Johari, Ozan Ozisik, Peter A.C. ‘t Hoen, Friederike Ehrhart, Anaïs Baudot, Chris T. Evelo, Bjarne Udd, Marco Roos, Eleni Mina

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Characterization of the complete plastid genome of Clivia mirabilis (Amaryllidaceae) by Ling Yue, Xiu-Li Feng, Dan Li, Hai-Hong Wu, Jing Meng, Xing-Hua Zhao

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Chloroplast genome characteristics and phylogenetic analysis of Macropanax rosthornii (Harms) C.Y. Wu ex G. Hoo (Araliaceae) by Shuxin Du, Huiying Huang, Shuhui Yang, Tianyi Gu, Mengli Zhou, Ruihong Wang

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The Role of Mitochondria from Mature Oocyte to Viable Blastocyst by Scott Chappel

“…The oocyte requires a vast supply of energy after fertilization to support critical events such as spindle formation, chromatid separation, and cell division. …”
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Mechanism(s) of Toxic Action of Zn2+ and Selenite: A Study on AS-30D Hepatoma Cells and Isolated Mitochondria by Elena A. Belyaeva, Nils-Erik L. Saris

“…Selenite induced a much higher intracellular ROS level (the early event) compared to Zn2+ but a lower membrane potential loss and a lower decrease of the uncoupled respiration rate of the cells, whereas the mtETC disturbance was the early and critical event in the mechanism of Zn2+ cytotoxicity. …”
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Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal by Rancilhac, Loïs, Miralles, Aurélien, Geniez, Philippe, Mendez-Aranda, Daniel, Beddek, Menad, Brito, José Carlos, Leblois, Raphaël, Crochet, Pierre-André

“…We identified four groups of populations within A. erythrurus, separated by barriers to gene flow, but even using nine independent nuclear makers the power of our approach was limited, and further investigation using genome-wide data will be required to resolve the phylogeographic history of this species. …”
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Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA) by Peter R. Rehani, Hanaa Iftikhar, Motowo Nakajima, Tohru Tanaka, Zaid Jabbar, Riyadh N. Rehani

“…5-Aminolevulinic acid (5-ALA) is a delta amino acid naturally present in every living cell of the human body. 5-ALA is produced in the mitochondria as the first product of the porphyrin synthesis pathway and composes heme; exogenously supplemented 5-ALA helps in upregulating mitochondrial functions. …”
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Dietary peptides in aging: Evidence and prospects by Khushwant S. Bhullar, Jianping Wu

“…Food derived bioactive peptides are characterized modulators of these pathways, while some verified in vivo and even clinically approved, and numerous others are under development. …”
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Association of p53 with Neurodegeneration in Parkinson’s Disease by Qiang Luo, Wei Sun, Yi-Fan Wang, Ji Li, Da-Wei Li

“…Pathogenic p53 integrates diverse cellular stresses and activate these downstream events to induce the degeneration of dopaminergic neurons; thus, it plays a crucial role in the pathogenesis of PD and appears to be a potential target for the treatment of the disease. …”
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Cell stress response to combined ionizing and non-ionizing radiation and magnetic fields: a review based on human buccal epithelium cells by К. А. Кузнецов, Г. М. Онищенко, О. Т. Ніколов

“…Results: Ultra-low doses of both IR itself and with EHF and MF have triggering effects which included variability of IR effect modification; the significance of even non-ionizing radiation effects was shown on the example of ultra-wideband microwaves irradiation. …”
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Bio-mimetic strategies to re-activate apoptotic cell death for cancer treatments by Andrea Venerando, Denise Lovison, Rossella De Marco

“…Apoptosis is a crucial process to maintain the correct balance between healthy cells and committed-to-death cells in every tissue. The internal (or mitochondrial) and external (or death receptor) pathways are responsible for driving a series of molecular events that lead to apoptosis by releasing pro-apoptotic proteins, such as B-cell lymphoma-2 (BCL-2) homology 3 (BH3)-only proteins and second mitochondria-derived activator of caspases/diablo inhibitor of apoptosis protein-binding mitochondrial protein (SMAC/DIABLO), that in turn activate the caspase family of proteases. …”
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Impact of hyper- and hypothermia on cellular and whole-body physiology by Toshiaki Iba, Yutaka Kondo, Cheryl L. Maier, Julie Helms, Ricard Ferrer, Jerrold H. Levy

“…Hyperthermia triggers inflammation, coagulation, and progressive multiorgan dysfunction, and, at levels above 40 °C, can even lead to cell death. Blood cells, particularly granulocytes and platelets, are highly sensitive to heat, which promotes proinflammatory and procoagulant changes. …”
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