Characterizing the regulatory effects of H2A.Z and SWR1-C on gene expression during hydroxyurea exposure in Saccharomyces cerevisiae. by Hilary T Brewis, Peter C Stirling, Michael S Kobor

“…However, given that growth defects of htz1Δ mutants are alleviated by simultaneous deletion of SWR1-C subunits, previous work examining the role of H2A.Z in gene expression regulation may be confounded by deleterious activity caused by SWR1-C when missing its H2A.Z substrate (apo-SWR1-C). Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”
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Medical researchers' perception of sharing of metadata from case report forms by Alexandra Meidt, Carolin Walter, Christoph U. Lehmann, Martin Dugas

“…The most frequently reported reason against CRF sharing was missing approval by the sponsor (160/301; 53.2%). …”
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Bayesian joint-regression analysis of unbalanced series of on-farm trials by Turbet Delof, Michel, Rivière, Pierre, Dawson, Julie C, Gauffreteau, Arnaud, Goldringer, Isabelle, van Frank, Gaëlle, David, Olivier

“…This dataset was severely unbalanced with more than 90% of GxE combinations missing. We compared various Bayesian Finlay-Wilkinson models and found that placing hierarchical distributions on model parameters and modelling residuals using a Student's t distribution jointly improved the estimates of main effects and interactions. …”
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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dsc... by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

“…While there was strong concordance of antimalarial resistance mutations between individual samples and pools, low-frequency variants in the pooled samples were often missed.ConclusionOverall, Pf-SMARRT is a robust tool for assessing parasite relatedness and antimalarial drug resistance markers from both individual and pooled samples. …”
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Focus group-supported development and psychometric exploration of an instrument to assess perceived physical exertion in nursing students by Eva Lorenz, Eva Grüne, Johanna Popp, Klaus Pfeifer, Johannes Carl

“…However, an appropriate tool to measure perceived physical exertion in nursing students is missing. Therefore, the goal of the present study was to design a questionnaire to assess perceived physical exertion in nursing students during their vocational education and to explore its factor structure. …”
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Determining an optimal case definition using mid-upper arm circumference with or without weight for age to identify childhood wasting in the Philippines. by Lyle Daryll Dimaano Casas, Jhanna Uy, Eldridge Ferrer, Charmaine Duante, Paluku Bahwere, Rene Gerard Galera, Alice Nkoroi, Behzad Noubary, Mueni Mutunga, Sanele Nkomani, Roland Kupka, Valerie Gilbert Ulep

“…MUAC alone, however, may miss identification of many wasted children, leading to untimely intervention and potentially death. …”
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Clinical and imaging features of co-existent pulmonary tuberculosis and lung cancer: a population-based matching study in China by Fan Zhang, Fei Qi, Yi Han, Hongjie Yang, Yishuo Wang, Guirong Wang, Yujie Dong, Hongxia Li, Yuan Gao, Hongmei Zhang, Tongmei Zhang, Liang Li

“…Abstract Background Co-existent pulmonary tuberculosis and lung cancer (PTB-LC) represent a unique disease entity often characterized by missed or delayed diagnosis. This study aimed to investigate the clinical and radiological features of patients diagnosed with PTB-LC. …”
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Association between psychological resilience, social support and oral health behaviours in patients with implant dentures by Tingting Cui, Liying Qiu, Deqiang Hou

“…Abstract Background With the improvement of living standards, implant dentures have become the choice of more and more patients with missing teeth. Dentures are not natural teeth, and may cause different degrees of negative impacts on patients in physiological, psychological and social aspects. …”
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Pituitary Stalk Interruption Syndrome: A Case and Literature Review by Anuja Choure, MD, Leena Shahla, MD

“…The objective of this report is to describe a patient with PSIS whose diagnosis was missed until adulthood. Case Report: A 42-year-old-female presented for evaluation of premature menopause, weight loss, and occasional dizziness. …”
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Spirituality-Based Intervention in Hypertension: EFfects on Blood PrEssure and EndotheliaL Function—FEEL Trial Results by Maria Emília Figueiredo Teixeira, Weimar Kunz Sebba Barroso, Andréa Araújo Brandão, Ana Luiza Lima Sousa, Roberto Esporcatte, Mário Henrique Elesbão de Borba, Ana Clara Neri Ávila Baleeiro, Beatriz Caldas Gonçalves, Enzo Inumaru, Enzo Mata de Sousa, Giovana Barros Leal, Henrique Soares de Araújo Pereira Farias, Juliana Alves de Souza, Lure Emilly Barreto da Silva, Matheus Canguçu de Paiva Queiroz, Frederico Rafael Moreira, Priscila Valverde de Oliveira Vitorino, John Eikelboom, Álvaro Avezum

“…Main outcomes were between group difference in change from baseline to 12 weeks in office and central BP, HBPM and FMD, using t-tests, analyses of covariance (ANCOVA) adjusting for baseline differences, and, in addition, missing data imputation as a sensitivity analysis. …”
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Enhance health evidence quality in classification tasks: A triangulation approach utilizing case-based reasoning and process features by Ruihua Guo, Ross Smith, Qifan Chen, Angus Ritchie, Simon Poon

“…Unlike clinical trials, real-world data used in ML are often gathered for multiple purposes, leading to bias and missing information for a specific classification task. …”
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Hepatitis C Prevalence on the Rise but Screening at Safety Net Institutions Lagging behind by Jarin Prasa, Syed S. Karim, Bobby Jacob, Paul Mustacchia

“…Our study findings suggest that a significant portion of patients in our community had missed opportunities for screening in our hospital. …”
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Risk prediction models for stress urinary incontinence after pelvic organ prolapse (POP) surgery: a systematic review and meta-analysis by Bi Jun Yu, Hao Chong He, Li Wang, Han Mei Shao, Ying Min Liu, Xiao Ying Yan, Jian Liu

“…All studies had a high risk of bias, primarily due to retrospective design, small sample sizes, single-center trials, lack of blinding, and missing data reporting. The meta-analysis revealed moderate heterogeneity (I² = 68.8%). …”
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Multiple Roles of the Y Chromosome in the Biology of Drosophila melanogaster by Roberto Piergentili

“…This is due to the intrinsic nature of this genetic element, namely, (1) its molecular composition (mainly transposable elements and satellite DNA), (2) its genetic inertia (lack of recombination due to its heterochromatic nature), (3) the absence of homology with the X (with the only exception of the nucleolar organizer), (4) the lack of visible phenotypes when it is missing (indeed, except for their sterility, X0 flies are normal males), and (5) its low density as for protein-coding sequences (to date, only 13 genes out of approximately 14,000 have been mapped on this chromosome in D. melanogaster, i.e., ~0.1% of the total). …”
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“We’re all in the same storm, but not all of us are in the same boat”: qualitative exploration of UK response-focused civil servants experiences of working from home during COVID-1... by Charlotte E. Hall, Samantha K. Brooks, Neil Greenberg, Dale Weston

“…Abstract Introduction The experiences of UK Government response-focused employees, who were considered frontline workers during the coronavirus response, are missing from current literature. Meeting the demands of being on the frontline, whilst also adjusting from a normal and practiced way of working to having to work from within one’s home, may bring a plethora of new barriers and facilitators associated with providing an effective pandemic response. …”
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A systematic scoping review to identify the design and assess the performance of devices for antenatal continuous fetal monitoring. by Kajal K Tamber, Dexter J L Hayes, Stephen J Carey, Jayawan H B Wijekoon, Alexander E P Heazell

“…Current methods utilised in clinical practice are intermittent and only provide a 'snapshot' of fetal wellbeing, thus key signs of fetal demise could be missed. Continuous fetal monitoring (CFM) offers the potential to alleviate these issues by providing an objective and longitudinal overview of fetal status. …”
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Optimal Dispatch of Reactive Power Using Modified Stochastic Fractal Search Algorithm by Thang Trung Nguyen, Dieu Ngoc Vo, Hai Van Tran, Le Van Dai

“…This manner results in the fact that some promising solutions around the high quality solutions can be missed. In order to tackle this restriction, the second modification of MSFS is to newly update the worst solutions in the first update and the best solutions in the second update. …”
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Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study by Daijiro Kabata, Ayumi Shintani, Masanori Akira, Masahiko Hara, Hideo Ishikawa, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Yukio Nagasaka, Kouji Yamamoto

“…Although not statistically significant by the adjusted analysis of variance with multiple imputation of missing variables, cryptogenic haemoptysis tended to show the most favourable outcome and non-tuberculous mycobacterium showed the worst outcome (adjusted p=0.250).Conclusions We demonstrated the safety and long-term efficacy of elective ssBAE using platinum coils and established that it can be a valuable therapeutic option for treating patients with haemoptysis.…”
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Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study. by Kate Alford, Stephanie Daley, Sube Banerjee, Jaime H Vera

“…Research is needed to understand the broad experiential impacts of living with these two complex, chronic conditions, to ensure interventions are meaningful to patients and potential benefits are not missed.…”
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Superplastic Forming/Diffusion Bonding of TA15 Titanium Alloy for Manufacturing Integrated Solid/Hollow Four-Layer Grid Lightweight Structure Components by Zheng Han, Yuhan Xing, Taiying Liu, Ning Zhang, Shaosong Jiang, Zhen Lu

“…The nondestructive testing results confirmed that the ribs of the component are fully formed, with no missing or broken ribs. The grid exhibits good geometry and high-quality diffusion bonding. …”
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