Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits by Yiying Hu, Alexander Hruscha, Chenchen Pan, Martina Schifferer, Michael K. Schmidt, Brigitte Nuscher, Martin Giera, Sarantos Kostidis, Özge Burhan, Frauke van Bebber, Dieter Edbauer, Thomas Arzberger, Christian Haass, Bettina Schmid

“…However, TDP-43 gain of function in the cytoplasm is still poorly understood since TDP-43 animal models recapitulating mis-localization of endogenous TDP-43 from the nucleus to the cytoplasm are missing. Methods CRISPR/Cas9 technology was used to generate a zebrafish line (called CytoTDP), that mis-locates endogenous TDP-43 from the nucleus to the cytoplasm. …”
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Risk factors for emergency presentation with lung and colorectal cancers: a systematic review by Una MacLeod, Elizabeth D Mitchell, Benjamin Pickwell-Smith

“…Five were graded ‘insufficient’, primarily due to missing information rather than methodological weakness. …”
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Ten proposed measures to improve vaccination: Health care providers’ perspectives on promoting the vaccination intake of children with special healthcare needs in China by Xiang Guo, Tianxing Feng, Meiyi Chen, Xuran Zhao, Xiangshi Wang, Yanling Ge, Zhonglin Wang, Zhuoying Huang, Mei Zeng

“…Introduction Children with special healthcare needs (CSHCN) often experience vaccination delays or missed vaccines in China. The coverage rate of the age-appropriate National Immunisation Programme vaccine was suboptimal. …”
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Adherence to Dihydroartemisinin-Piperaquine Treatment among Patients with Uncomplicated Malaria in Northern Ghana by Abraham Rexford Oduro, Samuel Chatio, Paula Beeri, Thomas Anyorigiya, Rita Baiden, Philip Adongo, Patricia Akweongo

“…The in-depth interviews documented day-by-day account of doses taken, number of tablets taken during each dose, time of each dose, reasons for any leftover or missed dose, and whether or not there was vomiting. …”
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Successful Non-Surgical Root Canal Treatment on Auto-Transplanted Maxillary Premolar with Apical Periodontitis by Christopher M. Naglieri, Ellie Bash, Glen A. Karunanayake, Carlos H. R. Camargo, Takashi Komabayashi

“…Auto-transplantation is a procedure that replaces traumatized or congenitally missing teeth. While most auto-transplanted teeth are successfully integrated into recipient sites, the donor tooth may develop apical periodontitis, causing early failure. …”
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JEAN BODIN'S NOTION OFSOVEREIGNTY, GOOD GOVERNANCE AND NTHE QUEST FOR SOCIOPOLITICALADVANCEMENT IN NIGER by EKUASE INNOCENT O., COLLINS OKONKWO, EDOGIAWERIE MORRIS K.O.

“… Bodin's far reaching analysis on the sovereign state and good governance shows that he did not miss words when he recommended that the management of the state shouldbe separated from the management of the church. …”
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Evaluation of Zenith Tropospheric Delay Derived from Ray-Traced VMF3 Product over the West African Region Using GNSS Observations by Samuel Osah, Akwasi A. Acheampong, Collins Fosu, Isaac Dadzie

“…To address this challenge as a means of providing an alternative data source to improve the continuous availability of ZTD data and as a backup data in the event that the IGS site data are missing or unavailable in West Africa, this paper compares the sitewise operational Vienna Mapping Functions 3 (VMF3) ZTD product with the IGS final ZTD product over five IGS stations in West Africa. …”
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Epigenetics of suicidal behavior by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, S. B. Malykh, V. V. Viktorov, E. K. Khusnutdinova

“…To solve this problem and interpret the missing relationship between the environment and the genome, promising results were obtained from a study of epigenetic factors, which affected the expression of a number of candidate genes involved in brain functioning in suicidal behavior. …”
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Evaluation of the location of posterior superior alveolar artery and infraorbital foramen originating from the same source by using cone beam computed tomography by Kübra Çam, Ayse Zeynep Zengin

“…Material and method Bilateral maxillary sinuses were analysed retrospectively in 170 patients with no missing teeth in the maxillary posterior region. The largest locations of PSAA and IOF in the maxillary sinus were determined and their size, shape, location in relation to the teeth and distances from anatomical points were evaluated. …”
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Developing a Transparent Anaemia Prediction Model Empowered With Explainable Artificial Intelligence by Muhammad Sajid Farooq, Muhammad Hassan Ghulam Muhammad, Oualid Ali, Zahid Zeeshan, Muhammad Saleem, Munir Ahmad, Sagheer Abbas, Muhammad Adnan Khan, Taher M. Ghazal

“…The model simulation results are showing promising results in terms of the accuracy (98.13%) and the miss-rate (1.87%) which are the superior performance compared to the previous published approaches.…”
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Prevalence and risk factors associated with prehypertension in Shunde District, southern China by Yuli Huang, Yunzhao Hu, Xiaoyan Cai, Wenke Qiu, Changhua Liu, Dingji Zhu, Jinghai Hua, Yanxian Wu, Dingli Xu

“…Prehypertension was further divided into low-range (BP 120–129/80–84 mm Hg) and high-range (BP 130–139/85–89 mm Hg) subgroups.Outcome measures The prevalence of prehypertension and the combined cardiovascular risk factors within the prehypertensive subgroups.Results Of the 5362 initially reviewed cases (aged ≥35 years), 651 were excluded because of missing data. The proportions of optimal BP, prehypertension and hypertension were 39.1%, 38.6% and 22.3%, respectively. …”
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How Much Do We Know about the Biopsychosocial Predictors of Glycaemic Control? Age and Clinical Factors Predict Glycaemic Control, but Psychological Factors Do Not by Mohammad Farris Iman Leong Bin Abdullah, Hatta Sidi, Arun Ravindran, Paula Junggar Gosse, Emily Samantha Kaunismaa, Roslyn Laurie Mainland, Norlaila Mustafa, Nurul Hazwani Hatta, Puteri Arnawati, Amelia Yasmin Zulkifli, Luke Sy-Cherng Woon

“…Longer duration of diabetes mellitus and a greater number of days of missed medications predicted poor glycaemic control, while older age and overall self-perception of QOL protected against poor glycaemic control. …”
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The rise of congenital syphilis in Canada: threats and opportunities by Ashorkor Tetteh, Victoria Moore

“…These trends call for a closer look at missed opportunities for testing, diagnosis, treatment, and follow-up of pregnant individuals. …”
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Thresholds for clinical practice that directly link handgrip strength to remaining years of life: estimates based on longitudinal observational data by Sergei Scherbov, Sonja Spitzer, Nadia Steiber

“…Objective Muscle strength is a powerful predictor of mortality that can quickly and inexpensively be assessed by measuring handgrip strength (HGS). What is missing for clinical practice, however, are empirically meaningful cut-off points that apply to the general population and that consider the correlation of HGS with gender and body height as well as the decline in HGS during processes of normal ageing. …”
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Men care too: a qualitative study examining women’s perceptions of fathers’ engagement in early childhood development (ECD) during an ECD program for HIV-positive mothers in Malawi... by Linda Richter, Thomas J Coates, Tijana Temelkovska, Pericles Kalande, Evelyn Udedi, Laurie Bruns, Siyenunu Mulungu, Julie Hubbard, Sundeep Gupta, Kathryn Dovel

“…Objectives Integrated early childhood development (ECD) and prevention of mother-to-child transmission (PMTCT) interventions rarely target fathers, a missed opportunity given existing research demonstrating that father involvement improves maternal and child outcomes. …”
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Effects of a Cognitive-Functional Intervention Method on Improving Executive Function and Self-Directed Learning in School-Aged Children with Attention Deficit Hyperactivity Disord... by Mi Ji Kim, Hae Yean Park, Eun-Young Yoo, Jung-Ran Kim

“…All three participants presented statistically significant changes with a number of near-misses of CCTT and color words score of Stroop test during the intervention. …”
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Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…New, remotely delivered diagnostic assessments that can detect early stage NPDs by profiling speech could enable earlier intervention and fewer missed diagnoses. The feasibility of collecting speech data remotely in those with NPDs should be established.Methods and analysis The present study will assess the feasibility of obtaining speech data, collected remotely using a smartphone app, from individuals across three NPD cohorts: neurodegenerative cognitive diseases (n=50), other neurodegenerative diseases (n=50) and affective disorders (n=50), in addition to matched controls (n=75). …”
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A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium. by Andrew Larkins, Mieghan Bruce, Carlotta Di Bari, Brecht Devleesschauwer, David M Pigott, Amanda Ash

“…Published data relating to disease models, data sources, disability-adjusted life years, sensitivity, uncertainty, missing data, and key limitations were collected.<h4>Results</h4>15 studies were included for review, with seven global and eight national or sub-national estimates. …”
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Clinicopathological spectrum of central nervous system germ cell tumors: A single-institution retrospective study by Sreelekha Appasani, Neelima Radhakrishnan, Anitha Mathews

“…Conclusion: Though histology and immunohistochemistry were diagnostic, correlation between serum and/or CSF marker was essential to rule out GCT component(s) that may be missed on biopsy due to sampling error.…”
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KANDiff: Kolmogorov–Arnold Network and Diffusion Model-Based Network for Hyperspectral and Multispectral Image Fusion by Wei Li, Lu Li, Man Peng, Ran Tao

“…This work introduces an effective solution for addressing the challenges posed by missing high-resolution hyperspectral images (HRHS) data, which is essential for tasks including landing site selection and resource exploration within the realm of deep space exploration.…”
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