Neuroprotective Effects of Eugenol Acetate Against Ischemic Stroke by Chen L, Zhang R, Xiao J, Liang Y, Lan Z, Fan Y, Yu X, Xia S, Yang H, Bao X, Meng H, Xu Y, Yu L, Zhu X

“…Liqiu Chen,1,2,* Ran Zhang,1,2,* Jing Xiao,1,2,* Ying Liang,1,2 Zhen Lan,3 Yingao Fan,2 Xi Yu,2 Shengnan Xia,2– 5 Haiyan Yang,2– 5 Xinyu Bao,2– 5 Hailan Meng,1– 6 Yun Xu,1– 6 Linjie Yu,1– 6 Xiaolei Zhu1– 6 1Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China; 2Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People’s Republic of China; 3Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, 210008, People’s Republic of China; 4State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases, Nanjing University, Nanjing, 210008, People’s Republic of China; 5Jiangsu Provincial Key Discipline of Neurology, Nanjing, 210008, People’s Republic of China; 6Nanjing Neurology Medical Center, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Linjie Yu; Xiaolei Zhu, Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China, Email yulinjie126@126.com; zhuquelee@126.comObjective: To explore the neuroprotective effect of Eugenol Acetate (EA) on post-stroke neuroinflammation and investigate the underlying mechanisms.Methods: For in vitro experiments, primary microglia were pre-incubated with EA for 2 hours, followed by lipopolysaccharide (LPS) stimulation for 24 hours or Oxygen-Glucose Deprivation (OGD) treatment for 4 hours. …”
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The NANOGrav 15 Yr Data Set: Removing Pulsars One by One from the Pulsar Timing Array by Gabriella Agazie, Akash Anumarlapudi, Anne M. Archibald, Zaven Arzoumanian, Jeremy G. Baier, Paul T. Baker, Bence Bécsy, Laura Blecha, Adam Brazier, Paul R. Brook, Sarah Burke-Spolaor, J. Andrew Casey-Clyde, Maria Charisi, Shami Chatterjee, Tyler Cohen, James M. Cordes, Neil J. Cornish, Fronefield Crawford, H. Thankful Cromartie, Kathryn Crowter, Megan E. DeCesar, Paul B. Demorest, Heling Deng, Lankeswar Dey, Timothy Dolch, Elizabeth C. Ferrara, William Fiore, Emmanuel Fonseca, Gabriel E. Freedman, Emiko C. Gardiner, Nate Garver-Daniels, Peter A. Gentile, Kyle A. Gersbach, Joseph Glaser, Deborah C. Good, Lydia Guertin, Kayhan Gültekin, Jeffrey S. Hazboun, Ross J. Jennings, Aaron D. Johnson, Megan L. Jones, Andrew R. Kaiser, David L. Kaplan, Luke Zoltan Kelley, Matthew Kerr, Joey S. Key, Nima Laal, Michael T. Lam, William G. Lamb, Bjorn Larsen, T. Joseph W. Lazio, Natalia Lewandowska, Tingting Liu, Duncan R. Lorimer, Jing Luo, Ryan S. Lynch, Chung-Pei Ma, Dustin R. Madison, Alexander McEwen, James W. McKee, Maura A. McLaughlin, Natasha McMann, Bradley W. Meyers, Patrick M. Meyers, Hannah Middleton, Chiara M. F. Mingarelli, Andrea Mitridate, Christopher J. Moore, Cherry Ng, David J. Nice, Stella Koch Ocker, Ken D. Olum, Timothy T. Pennucci, Benetge B. P. Perera, Nihan S. Pol, Henri A. Radovan, Scott M. Ransom, Paul S. Ray, Joseph D. Romano, Jessie C. Runnoe, Alexander Saffer, Shashwat C. Sardesai, Ann Schmiedekamp, Carl Schmiedekamp, Kai Schmitz, Brent J. Shapiro-Albert, Xavier Siemens, Joseph Simon, Magdalena S. Siwek, Sophia V. Sosa Fiscella, Ingrid H. Stairs, Daniel R. Stinebring, Kevin Stovall, Abhimanyu Susobhanan, Joseph K. Swiggum, Stephen R. Taylor, Jacob E. Turner, Caner Unal, Michele Vallisneri, Alberto Vecchio, Sarah J. Vigeland, Haley M. Wahl, Caitlin A. Witt, David Wright, Olivia Young

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