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    Cytotoxic Activity of Bisphosphonic Derivatives Obtained by the Michaelis–Arbuzov or the Pudovik Reaction by Zsuzsanna Szalai, Janka Bednárik, Boldizsár Szigfrid Tóth, Angéla Takács, Szilárd Tekula, László Kőhidai, Konstantin Karaghiosoff, László Drahos, György Keglevich

    Published 2025-01-01
    “…<b>Methods:</b> Methylenebisphosphonates may be obtained by the Michaelis–Arbuzov reaction of suitably α-substituted methylphosphonates and trialkyl phosphites or phosphinous esters, while the hydroxy-methylene variations are prepared by the Pudovik reaction of α-oxophosphonates and different >P(O)H reagents, such as diethyl phosphite and diarylphosphine oxides. …”
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    Michaelis-Menten kinetics, the operator-repressor system, and least squares approaches by Karl Peter Hadeler

    Published 2013-07-01
    “…The Michaelis-Menten (MM) function is a fractional linear function depending on two positive parameters.These can be estimated by nonlinear or linear least squares methods.The non-linear methods, based directly on the defect of the MM function, can fail and not produce any minimizer.The linear methods always produce a unique minimizer which, however, may not be positive. …”
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    Mancha negra de los cítricos by Megan M. Dewdney, Natalia A. Peres

    Published 2012-08-01
    “…Este documento es una hoja de dos páginas ilustrativas para la identificación de la mancha negra de los cítricos. This 2-page fact sheet was written by Megan M. …”
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    Mancha negra de los cítricos by Megan M. Dewdney, Natalia A. Peres

    Published 2012-08-01
    “…Este documento es una hoja de dos páginas ilustrativas para la identificación de la mancha negra de los cítricos. This 2-page fact sheet was written by Megan M. …”
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    La lucha por Guayaquil by Felipe Burbano de Lara

    Published 2009-01-01
    “…Disputa que es examinada a partir de tres ejes: la lucha contra el neoliberalismo, la construcción de un proyecto estatal nacional y la búsqueda por una por una hegemonía política de Alianza País. …”
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