Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and l... by Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir

“…However, there is a lack of longitudinal studies to quantify the concentrations of maternal apolipoproteins from preconception to postpartum and their associations with maternal metabolic health and offspring birth outcomes. Methods: Quantification of apolipoproteins was performed on maternal plasma samples (N = 243 trios) collected at preconception, 26–28 weeks’ pregnancy, and three months postpartum in the Singapore PREconception Study of long-Term maternal and child Outcomes (S-PRESTO) cohort study. …”
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Evaluation of long‐acting cabotegravir safety and pharmacokinetics in pregnant women in eastern and southern Africa: a secondary analysis of HPTN 084 by Sinead Delany‐Moretlwe, Brett Hanscom, Xu Guo, Clemensia Nkabiito, Patricia Mandima, Patricia Ntege Nahirya, Juliet Mpendo, Muchaneta Bhondai‐Mhuri, Nyaradzo Mgodi, Rebecca Berhanu, Jennifer Farrior, Estelle Piwowar‐Manning, Susan L. Ford, Craig W. Hendrix, Alex R. Rinehart, James F. Rooney, Adeola Adeyeye, Raphael J. Landovitz, Myron S. Cohen, Mina C. Hosseinipour, Mark A. Marzinke, the HPTN 084 Study Team

“…We report on the safety and CAB‐LA pharmacokinetics in pregnant women during the blinded period of HPTN 084. Methods Participants were randomized 1:1 to either active cabotegravir (CAB) plus tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) placebo or active TDF/FTC plus CAB placebo. …”
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Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging by Lukas Hingerl, Bernhard Strasser, Simon Schmidt, Korbinian Eckstein, Guglielmo Genovese, Edward J. Auerbach, Andrea Grant, Matt Waks, Andrew Wright, Philipp Lazen, Alireza Sadeghi-Tarakameh, Gilbert Hangel, Fabian Niess, Yigitcan Eryaman, Gregor Adriany, Gregory Metzger, Wolfgang Bogner, Małgorzata Marjańska

“…Here, we present the preliminary findings from 3D MR spectroscopic imaging (MRSI) of the human brain conducted with the world's first 10.5 T whole-body MR system. Methods: Employing a custom-built 16-channel transmit and 80-channel receive MR coil at 10.5 T, we conducted MRSI acquisitions in six healthy volunteers to map metabolic compounds in the human cerebrum in vivo. …”
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Influence of Exposure to Different Green Rooftop Spaces on Stress Restoration of College Students by Zhixiong ZHUO, Liang DONG

“…Therefore, this research explores the influence of exposure to green rooftop space on the physical and psychological restoration of college students from both physiological and psychological perspectives through a field experiment.MethodsIn order to determine the restorative effects of green rooftops on physical and psychological health, three types of green rooftop spaces (water space, wooden plaza, and ecological sunroom) and a control group (non-green rooftop space) in the Experimental Building of Architecture Discipline of Huaqiao University are selected to explore the restorative potentials of green rooftop space. …”
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Économie végétale à partir des études carpologiques du boulevard Dr Henri-Henrot à Reims/Durocortorum by Véronique Matterne

“…The increase in the number of mortars testifies to the importance of spices and the preparation of spiced and carefully seasoned sauces; cooking methods favored for stews or other dishes that are simmered. …”
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Study on the status of liver function abnormalities and its related factors in patients with severe mental disorders in Shanghai community by ZHANG Yixuan, CHEN Chunmei, ZHU Youwei, ZHU Yi, HE Siyuan, LIU Yanli, WANG Na, CAI Jun, XIE Bin, ZHANG Weibo

“…ObjectiveTo investigate the status of liver function abnormalities in patients with severe mental disorder (SMD) in Shanghai community, to explore the related factors to abnormal liver function in patients with SMD, and to analyze the effects of the types of mental disorders and medication status on liver function abnormalities.MethodsThe patients with SMD in Jinshan District, Minhang District, Hongkou District and Xuhui District of Shanghai were selected as the research subjects. …”
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Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…However, expansion of DCD lung transplants requires a comparison of these indicators to DBD donors for application of similar parameters to increase the rate of DCD lung recovery to ensure that viable DCD organs are not discarded due to overly stringent donor and organ requirements. Methods: We performed a retrospective analysis of United Network for Organs Sharing (UNOS) Organ Procurement and Transplantation Network/UNOS STAR (Standard Analysis and Research) database. …”
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Utilisation et résistance d’un nouveau jouet introduit chez des macaques cynomolgus hébergés en milieu standard ou appauvri by Helen Beyer, Agnès Loison, Fanélie Wanert

“…Les comportements d’interaction exprimés par les animaux envers le nouveau jouet ont été filmés puis relevés à l’aide du logiciel The Observer (Noldus, Pays-Bas) via la méthode de focal sampling lors de quatre périodes d’observations continues de deux heures réparties sur les 48 heures suivant l’introduction du jouet (deux heures le matin et deux heures l’après-midi, pendant deux jours). …”
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A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study by Li Y, Ren X, Wang Q, Shen S, Li Y, Qian X, Tang Y, Jia J, Zhang H, Ding J, Song Y, Zhang S, Wang S, Xu Y, Jiang Y, He X, Dai M, Zhong L, Xiong Y, Pan Y, Wang M, Shao H, Cai H, Huang L, Wang H

“…This study aimed to develop a risk prediction model for IPA by integrating clinical and microbiological characteristics.Methods: This retrospective study was conducted in adult intensive care units (ICUs) of 17 medical centers in China. …”
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Estimating Suitable Areas for Dry Almond (Amygdalus communis L.) Cultivation Development in Fars Province using Geographic Information System (GIS) by Ayatollah Karami, Alireza Salehi, Vida Aliyari

“…Therefore, this study focuses on analyzing land suitability for almond cultivation in Fars province by integrating the Analytic Hierarchy Process (AHP) and fuzzy algorithm with Geographic Information System (GIS).Materials and MethodsIn order to estimate the extent of suitable areas for dry almond cultivation in Fars province, four criteria (including climatic, topographic, environmental adaptation, and socio-economic) and 14 sub-criteria were used. …”
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New Parameters for Impedance–pH Monitoring in Diagnosing Gastroesophageal Reflux Disease and Predicting its Severity by O. A. Storonova, A. S. Trukhmanov, A. A. Makushina, A. V. Paraskevova, V. T. Ivashkin

“…The authors set out to assess the values of MNBI and the PSPW index as additional criteria improving the diagnostic efficacy of impedance-pH monitoring, the completeness of clinical phenotyping of gastroesophageal reflux disease (GERD), as well as determining the probability of a more severe disease course. Materials and methods. A total of 60 patients aged 19 to 71 (mean age 44.7 years) participated in the study: 30 patients with erosive reflux disease (ERD), 30 with non-erosive reflux disease (NERD) and 20 healthy volunteers aged 26 to 65 (mean age 45.2 years). …”
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Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Li... by Di Jin, Kai Kang, Bing-zhu Yan, Jian-nan Zhang, Jun-bo Zheng, Zhi-hui Wang, Di Wu, Yu-jia Tang, Xin-tong Wang, Qi-qi Lai, Yang Cao, Hong-liang Wang, Yang Gao

“…Our study aims to identify a novel and simple clinical predictor of 90-day transplant-free mortality in adult patients with ALF undergoing PE. Methods. This retrospective study contained adult patients with ALF undergoing PE from the Medical ICU (MICU) in the Second Affiliated Hospital of Harbin Medical University between January 2017 and December 2020. …”
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The value of sex hormones and sex hormone-binding globulin in metabolic dysfunction-associated fatty liver disease among boys with obesity by Ying Wang, Shuyi Yang, Suming Zhang, Suming Zhang, Ye Yang, Siqing Li, Siqing Li, Meiyu Zhang, Meiyu Zhang, Xiaona Li, Hua Bai, Peiliang Luo, Yingdi Yuan, Yingdi Yuan

“…ObjectiveThis study aims to investigate the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and sex hormones and sex hormone-binding globulin (SHBG) in boys with obesity.MethodsRetrospective analysis of metabolic indicators and sex hormone levels in boys with obesity who sought medical attention at the First People’s Hospital of Lianyungang City from January 2020 to December 2023. …”
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HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in... by Augustine T Choko, Elizabeth L Corbett, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Cheryl C Johnson, Doreen Sakala, Thokozani Kalua, Moses Kumwenda, Richard Hayes, Katherine Fielding

“…We investigated the impact of HIVST alone or with additional interventions on the uptake of testing and linkage to care or prevention among male partners of antenatal care clinic attendees in a novel adaptive trial.<h4>Methods and findings</h4>An adaptive multi-arm, 2-stage cluster randomised trial was conducted between 8 August 2016 and 30 June 2017, with antenatal care clinic (ANC) days (i.e., clusters of women attending on a single day) as the unit of randomisation. …”
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Performance evaluation of four cascade impactors for airborne ultrafine-particle (UFP) collection: the influence of particle type, concentration, mass, and chemical nature by E. Eckenberger, A. Mittereder, N. Gawlitta, N. Gawlitta, J. Schnelle-Kreis, J. Schnelle-Kreis, M. Sklorz, D. Brüggemann, R. Zimmermann, R. Zimmermann, A. C. Nölscher

“…However, their small mass presents challenges for sampling and chemical characterization methods. Therefore, we conducted a comprehensive characterization and comparison of four cascade impactors suitable for separating and collecting UFPs – namely, the 120R Micro-Orifice Uniform Deposit Impactor (120R MOUDI-II), ultraMOUDI, electrical low-pressure impactor (ELPI), and personal nanoparticle sampler (PENS) – under controlled laboratory conditions and in a field application.…”
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Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…However, the exploration and production of deep CBM are still confronted with many technical challenges, and there is a lack of studies on key experimental technologies related to the geological characteristics and engineering assessment of deep CBM reservoirs, the occurrence characteristics and production mechanisms of gas and water, the formulation of production systems, and methods for enhanced CBM recovery. Advances in ResearchGiven the characteristics of deep coal seams and CBM, this study identifies four challenges in the exploration and exploitation of deep coal seams: the collection of large coal samples, the high-temperature, high-pressure, and high-stress in-situ conditions, high-precision characterization and desorption of sub-nano- to nano-scale micropores, and the accurate determination of gas content. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…A combination of lithium carbonate and valproic acid (VPA-Li) was shown to inhibit motor neuron death and delay disease progression. Methods: Outpatients with a typical ALS presentation were enrolled in a randomized, placebo-controlled trial to assess the efficacy of orally administered VPA-Li. …”
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Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical f... by Kai Li, Jingjing Wang, Yuqin Rao, Fanhui Zheng, Ying Chen, Bo Zhai, Jintao Hong, Dao Wang, Chen Wang, Bao Liu

“…This study aims to examine the associations between key determinants of lifestyle behavior and various multimorbidity patterns. Methods In a cross-sectional sample of older adults (aged 60–79) from the Fifth National Physical Fitness Surveillance in Shanghai, latent class analysis (LCA) was used to identify multimorbidity patterns among 9 chronic diseases. …”
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Current situation of central nervous system tumour survivors in a spanish hospital by Ivonne Marcela Rincón-Mantilla, Blanca Herrero, Elena Herranz Valero, Fernando Robles-Bermejo, Alba Herrera-Olivares, Felisa Vázquez-Gómez, Álvaro Lassaletta

“…The aim of our study was to evaluate late morbidity, health-related quality of life (HRQoL), self-esteem, functional status, adaptive behaviour, physical activity and social outcomes such as education, employment, relationship status and possession of a driver’s license, in addition to the role of LT effects of radiotherapy (RTx) on these outcomes. Methods: The study included 111 CNS tumour survivors with a minimum of 10 years of follow-up. …”
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Evaluating the Impact of Simulated Patients on Knowledge, Skills and Attitudes of Laypeople Following a Basic First Aid Course: Protocol for a Cluster-Randomized Controlled Trial

“…The alternative is that knowledge, skills and self-efficacy will be influenced by using simulated patients during training. Methods: This study will be a cluster-randomized controlled trial, that will take place from September 2018 to June 2020. …”
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