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1921
Whole-Genome Methylation Sequencing Analysis and Functional Verification of LIM-Homeobox Family Genes in Cervical Cancer
Published 2025-01-01“…In this study, complete genome methylation sequencing (BS-Seq) technology was used to analyze the genome-wide methylation of patients with cervical cancer before and after radiotherapy.Methods: Three pairs of cervical squamous cell carcinoma samples were collected from patients before and after radiotherapy in July 2020. …”
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1922
The Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide
Published 2024-11-01“…Introduction: 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide is a new selective type II carbonic anhydrase inhibitor with local action through instillation into the eyes. …”
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1923
Microwave Assisted Synthesis of N-Substituted-7-hydroxy-4-methyl-2-oxoquinolines as Anticonvulsant Agents
Published 2011-01-01“…The reaction of resorcinol with ethylacetoacetate yielded the 7-hydroxy-4-methyl coumarin (1), which on treatment with benzidine gives 1-(4ʹ-amino-biphenyl-4-yl)-7-hydroxy-4-methyl-1H-quinolin-2-one (2). 1-{4ʹ-[(Substituted benzylidene)-amino]-biphenyl-4-yl}-7-hydroxy-4-methyl-1H-quinolin-2-one (3a-j) were obtained by reacting 1-(4ʹ-amino-biphenyl-4-yl)-7-hydroxy-4-methyl-1H-quinolin-2-one (2) with different substituted aromatic aldehydes in presence of glacial acetic acid by microwave irradiation. …”
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1924
PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
Published 2023-04-01“…Moreover, PRMT5 signals high glucose to increase the methylation modification of ENO1. Together, our data reveal a novel role of PRMT5 in promoting ovarian cancer growth by controlling glycolysis flux mediated by methylating ENO1, and highlights that PRMT5 may represent a promising therapeutic target for treating ovarian cancer.…”
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1925
Kinetic Study of the Removal of Methyl Orange Dye by Coupling WO3/H2O2
Published 2022-01-01“…In the present work, the heterogeneous Fenton-like process was employed to investigate the kinetic models of the degradation of methyl orange (MO) using tungsten oxide/hydrogen peroxide couple. …”
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1926
Effect of 17α-methyl testosterone on sex reversal and growth performance of Nile tilapia,Oreochromis niloticus
Published 2023-12-01“… The present study aimed at developing all-male Nile tilapia using17α-methyl testosterone(17α-MT) along with its growth and feed utilization performances. …”
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1927
A pathway to cyclic carbonates: Cycloaddition of carbon dioxide to epoxidized methyl oleate on grafted heterogeneous catalysts
Published 2025-01-01“…Among the halide counter anions, bromide exhibited a superior performance, achieving 65 % conversion and 59 % cyclic carbonate yield by the end of the experiment, while the effect of various metal centra was less pronounced, with an overall improvement in the cyclic carbonate yield of less than 10 % compared to the metal-free catalyst. …”
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1928
A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers
Published 2025-01-01“…During the 12-month follow-up, methylation profiling and prolactin blood assessments showed that methylation markers clustered with NT specimens, which coincided with prolactinemia normalization, indicating successful tumor control after surgery. …”
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1929
Opicapone, a Novel Catechol-O-methyl Transferase Inhibitor, for Treatment of Parkinson's Disease "Off" Episodes
Published 2022-06-01“…Opicapone is a novel, peripherally acting Catechol-O-methyl transferase (COMT) inhibitor that is used as adjunctive therapy to carbidopa/levodopa for treatment and prevention of "off episodes." …”
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1930
The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis
Published 2025-02-01Subjects: Get full text
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1931
Methyl 2-amino-4-(morpholin-4-yl)benzo[d]thiazole-6-carboxylate tetartohydrate
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1932
Ion-pair complexes formation between fluoroquinolone antibiotics and methyl red and their use for the extraction-spectrophotometric analysis
Published 2017-09-01“…The new spectrophotometric methods of fluoroquinolones: enrofloxacin, norfloxacin, and ofloxacin determination with the methyl red are based on ion-pair complex formation between fluoroquinolones and methyl red in acidic medium at pH 3–4 and subsequent three times extraction of the reaction products by chloroform. …”
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1933
Cooperative condensation of RNA-DIRECTED DNA METHYLATION 16 splicing isoforms enhances heat tolerance in Arabidopsis
Published 2025-01-01“…Here, we identify a heat-responsive gene in Arabidopsis thaliana, RNA-DIRECTED DNA METHYLATION 16 (RDM16), which encodes a pre-mRNA splicing factor. …”
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1934
Methylated RNA Immunoprecipitation Sequencing Reveals the m6A Landscape in Oral Squamous Cell Carcinoma
Published 2022-01-01“…However, genes related to m6A modification in oral squamous cell carcinoma (OSCC) are still unclear. Here, methylated RNA immunoprecipitation sequencing (MeRIP-Seq) was performed to map the m6A landscape in OSCC and corresponding controls. …”
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1935
Research of the Methylation Status of miR-124a Gene Promoter among Rheumatoid Arthritis Patients
Published 2013-01-01“…Materials and Methods. DNA obtained from the frozen tissue of 7 RA samples, 6 osteoarthritis (OA) samples, and 3 healthy controls were undergoing bisulfite conversion and then analyzed for miR-124a promoter methylation using MSP assay. …”
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1936
LINC02282 promotes DNA methylation of TRIM6 by recruiting DNMTs to inhibit the progression of Parkinson's disease
Published 2025-03-01“…LINC02282 was mainly localized in the nucleus, and LINC02282 promoted the methylation of the tripartite motif-containing protein 6 (TRIM6) promoter to inhibit TRIM6 expression. …”
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1937
DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches
Published 2025-01-01“…Identifying cancer biomarkers through DNA methylation analysis is an efficient approach toward the detection of aberrant changes in epigenetic regulation associated with early-stage cancer types. …”
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1938
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1939
Effect of decitabine on PD-L2 methylation in whole blood of iodine-induced autoimmune thyroiditis rats
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1940
The relationship between IDH, P53 mutations, MGMT methylation with characteristics in high grade glioma patients
Published 2022-07-01Subjects: Get full text
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