Effect of Electroacupuncture Preconditioning on Inflammatory Factors of Rabbits after Spinal Cord Ischemia-Reperfusion Injury by Mengli YAO, Xianghua CHEN, Zhaohui CHEN, Hai WANG

“…Objective:To observe the effects of electroacupuncture preconditioning on the pathological changes of spinal cord tissue and the expression of inflammatory cytokines such as interleukin-1β(IL-1β), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), interleukin-1 receptor antagonist(IL-1Rα)after spinal cord ischemia-reperfusion injury, and to explore the protective mechanism of electroacupuncture on spinal cord ischemia-reperfusion injury in rabbits.Methods:A total of twenty-four New Zealand white rabbits were randomly divided into the sham operation group, the model group and the electroacupuncture group according to the random number table method, with eight cases in each group.The model was made by Zivin method in the model group and the electroacupuncture group, the abdominal cavity was opened after intravenous anesthesia at ear margin, the abdominal aorta was exposed and temporarily clamped, and the rabbit model of spinal cord ischemia-reperfusion injury was established after ischemia for thirty minutes.The model preparation and experimental animal treatment of the sham operation group were the same as those of the model group, however, the dissection was fully exposed without clamping the abdominal aorta.At thirty minutes before the induction of rabbit spinal cord ischemia-reperfusion model, SDZ-II electroacupuncture instrument was used to acupuncture bilateral"Xuanzhong"and"Yanglingquan"acupoints in the electroacupuncture group, intervention for thirty minutes.All rabbits were killed after intervention for twelve hours, and the L2-5 segments of spinal cord tissue were captured.HE staining method was used to observe the pathological changes of spinal cord tissues in the three groups; Immunohistochemical method was used to observe the localization and content changes of IL-1β, IL-6 and TNF-α; Enzyme-linked immunosorbent assay(ELISA)was used to detect the contents of IL-1β, IL-6, TNF-α and IL-1Rα in serum before modeling and 4, 8, 12 hours after ischemia-reperfusion.Results:①HE staining results: compared with the sham operation group, the number of neurons in spinal cord tissue in the model group decreased, the color of nucleus and cytoplasm of cells became lighter, and the boundary of nuclear membrane was not clear.In severe cases, the nucleus dissolved or even nucleolus disappeared, there were transparent areas around cells, and axons showed different degrees of degeneration such as enlargement, swelling and disappearance; compared with the model group, the number of neurons in the electroacupuncture group increased, the structure of most neurons was clear, the atrophy degree of nucleolus and nucleus was light, only a small amount of cells became deformed and necrosis, the damage degree of cells were lighter, and the density of surviving neurons increased.②Immunohistochemistry results: compared with the sham operation group, the expressions of IL-1β, IL-6 and TNF-α of spinal cord tissue in the model group were significantly increased(<italic>P</italic>&lt;0.05);compared with the model group, the contents of IL-1β, IL-6 and TNF-α in the spinal cord of rabbits in the electroacupuncture group were significantly decreased(<italic>P</italic>&lt;0.05).③ELISA results: Before modeling, there was no significant difference in the three groups(<italic>P</italic>&gt;0.05);compared with before modeling, the expressions of IL-1β, IL-6, TNF-α, IL-1Rα in serum of the three groups increased in different degrees at 4, 8 and 12 h after ischemia-reperfusion, with significantly significance(<italic>P</italic>&lt;0.05);compared with the sham operation group at the same time, the expressions of IL-1β, IL-6, TNF-α and IL-1Rα in the model group increased significantly at 4, 8 and 12 h after reperfusion(<italic>P</italic>&lt;0.05);compared with the model group at the same time, the expression of IL-1β and TNF-α in the electroacupuncture group decreased significantly at 4, 8, 12 h after reperfusion(<italic>P</italic>&lt;0.05).Conclusion:Electroacupuncture pretreatment can effectively alleviate the pathological injury of spinal cord and has a good protective effect on spinal cord ischemia-reperfusion injury, which may be related to inhibit the expression of IL-1β, IL-6 and TNF-α and promote the expression of IL-1Rα.…”
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Sherlock 3CGtip confirmation system for placement of peripherally inserted central catheters and related nursing countermeasures in a patient with double superior vena cava (1例双上腔静... by SONG Lanna (宋兰娜), WANG Yuan (王媛), WANG Wenxuan (王文萱), WANG Yu (王钰), ZHANG Na (张娜)

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Investigation on research innovation ability and training demand of clinical nursing staff (临床护理人员科研创新能力及培训需求现况调查) by YAN Xin (闫欣), QI Lixia (祁丽霞), WANG Zheng (王征), WEI Rui (卫蕊), LI Bin (李斌)

“…Objective To understand the scientific research innovation ability and training needs of clinical nursing staff at all levels of hospitals, so as to provide a reliable basis for the development of training programs to improve the scientific research ability and innovation level of clinical nursing staff. Methods Convenience sampling method was used to select a total of 1289 clinical nurses from 15 hospitals in the region as the research objects, and the questionnaire was used to investigate the scientific research innovation ability and training needs of clinical nursing staff. …”
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Application of fine nursing management for patients undergoing simultaneous bilateral lobectomy (精细化护理干预在同期双侧肺叶切除术患者中的应用) by BAI Xue (白雪), ZHAO Ying (赵莹), ZHENG Yue (郑悦), LIU Dongying (刘东颖), LI Huiyan (李惠艳)

“…Objective To investigate the effect of f fine nursing management for patients undergoing simultaneous bilateral lobectomy. Methods Totally 52 patients under simultaneous bilateral lobectomy were randomly divided into the control group and observation group, with 26 cases in each group. …”
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A Meta-analysis of the effect of five-element music therapy for patients with insomnia (五行音乐对失眠患者干预效果的Meta分析) by WU Yang (吴洋), GAI Haiyun (盖海云), MA Minghui (马明会)

“…Objective To evaluate the effect of five-element music therapy for patients with insomnia based on the results of Meta-analysis. Methods By searching Chinese databases such as CNKI, Wanfang Data and VIP, randomized controlled trials of five-element music therapy in treating insomnia were collected, and retrieval time-limit was from the establishment of the database to April 2022. …”
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Meta Analysis of Efficacy and Safety of Moxibustion on Neurogenic Bladder after Spinal Cord Injury by Xueqi HAN, Huirong HUANG, Zhongbiao XIU, Jingling WU, Qinyu LIU, Shaofang MIAO, Xiaona YAN

“…Objective:To evaluate the efficacy and safety of moxibustion in the treatment of neurogenic bladder (NB) after spinal cord injury (SCI) by Meta analysis, so as to provide evidence-based basis for improving the prognosis of NB after SCI.Methods:Data were searched from the databases of PubMed, Cochrane Library, Web of science, EMbase, OVID, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBMdisc), Wanfang Database (Wanfang Data) and Chinese Scientific Journal Database (VIP). …”
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Construction and application of grid management in nursing information construction (网格化管理在护理信息建设中的构建与应用) by WANG Tingting (王婷婷), GUO Xiujun (郭秀君), LIANG Junni (梁俊妮), HONG Yanyan (洪艳燕), QIAN Weiqing (钱卫庆)

“…Objective To explore the role of grid management mode in nursing information management, and to provide reference for nursing information management mechanism. Methods The nursing units were divided into large, medium and small grids, and the viewpoints and methods based on the grid management theory were established to form a plane and deep network management method with clear division of labor and appropriate coordination. …”
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Effects of Repetitive Transcranial Magnetic Stimulation Combined with Balance Acupuncture Treatment on Sleep Quality and Psychology in Patients after Stroke by YANG Huazhong, CUI Jinlong, FAN Hexin, XIONG Zhonghui, YAO Yuanmian, ZHOU Shasha, CUI Wenxiu, SUN Tianbao

“…ObjectiveTo observe the clinical effects of repetitive transcranial magnetic stimulation (rTMS) combined with balance acupuncture treatment on sleep quality and psychology in patients after stroke.MethodsA total of 60 patients with post-stroke sleep disorder admitted at Xiangya Boai Rehabilitation Hospital were selected and randomly divided into three groups: rTMS group (psychotherapy+rTMS), balance acupuncture group (psychotherapy+balance acupuncture treatment), and combination group (psychotherapy +rTMS+balance acupuncture), with 20 cases in each group. …”
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不同生活环境天鹅肠道菌群的多样性分析 by 曹乐天 1 王璐阳 1 张艺凡 2 张凯慧 1 董睿龙 2 王悦欣 1 李丰波 2 张龙现 1

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Application of BOPPPS combined with dynamic scenarios simulation in ICU clinical nursing teaching (BOPPPS结合动态情景模拟在ICU护理教学中的应用) by CHEN Xi (陈曦), LI Baoyu (李宝妤), WANG Lingling (王玲玲), ZHANG Chao (张超), XIU Limin (修立敏)

“…In the clinical teaching of ICU, 27 students in the control group adopted conventional teaching method, and 30 students in the experimental group adopted BOPPPS combined with dynamic scenarios simulation teaching method. …”
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Treatment Efficacy of Open Kinetic Chain Combined with Closed Kinetic Chain Exercise Training on Patients after Anterior Cruciate Ligament Reconstruction by GAO Peng, JIANG Xin, WANG Junzhe, WANG Hongyu, LIU Chengyao

“…ObjectiveTo observe the effect of open kinetic chain (OKC) combined with closed kinetic chain (CKC) exercise training on motor function of knee or lower limb, balance function, quadriceps isokinetic muscle strength and atrophy degree after anterior cruciate ligament (ACL) reconstruction.MethodsA total of 84 patients who underwent knee ACL reconstruction in the Jinan Zhangqiu District People's Hospital from January 2020 to October 2021 were randomly divided into OKC group, CKC group, equal combination group and adjusted combination group, with 21 cases in each group. …”
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Application of family somatosensory game intervention in rehabilitation of COPD patients after discharge from hospital (家庭体感游戏干预在COPD患者出院后康复中的应用研究)... by FANG Huaqin (方华琴)

“…Objective To explore the role of family somatosensory game intervention in post hospital rehabilitation of patients with chronic obstructive pulmonary disease (COPD) after discharge from hospital. Methods Totally 62 COPD patients discharged from hospital from March 2018 to June 2019 were selected as the research objects. …”
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A qualitative study of stigma among disabled elders with stroke and their primary caregivers (脑卒中失能老人及其主要照顾者病耻感的质性研究) by KE Ke (柯珂), HE Juanfeng (贺娟凤), WANG Wei (汪维)

“…Objective To investigate the experience of stigma among disabled elders with stroke and their primary caregivers, analyze potential reasons and measures to relieve the feeling of stigma, and provide a reference for medical workers to carry out targeted psychological care and comprehensive interventions. Methods Phenomenological research design and semi-structural interviews were conducted on 13 disabled elders with stroke and their primary caregivers, and the collected data were analyzed with the method of Colaizzi Phenomenological analysis. …”
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Mechanism of DMOC in Diabetes Mellitus with Liver Fibrosis by Zizhi XIAO, Hong SHI, Huanwen RAO, Lifen LUO

“…Objective:To establish a rat model of high-fat and high-sugar diet combined Streptozotocin(STZ)to explore the anti-oxidative, anti-inflammatory and anti-fibrotic mechanisms of the dendrobium mixture in order cycle method(DMOC)in diabetes mellitus with liver fibrosis.Methods:Forty healthy and clean male Sprague Dawley rats at five weeks of age were randomly divided into the control group(<italic>n</italic>=10, basic diet), the control intervention group(<italic>n</italic>=10, basic diet and DMOC), the model group(<italic>n</italic>=10, high fat and high glucose combined STZ)and the model intervention group(<italic>n</italic>=10, high fat and high glucose, STZ combined DMOC)after one week of adaptive feeding. …”
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Research hotspots and trends in the field of quality of life of oral cancer patients: A visual analysis based on CiteSpace (基于CiteSpace口腔癌患者生活质量研究热点的可视化分析)... by YANG Ting (杨婷), CHEN Siyi (陈思忆), ZHENG Xiaodan (郑晓丹), YANG Yi (杨怡)

“…Objective To explore the research hotspots and trends in the field of quality of life of oral cancer patients, so as to provide a guiding basis for quality of life studies on oral cancer patients in China. Methods Using the literature related to the quality of life of oral cancer patients published in Web of Science from 2000 to 2022 as the data source. …”
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Mechanism of Delaying Cartilage Degeneration in Knee Osteoarthritis with Rongjin Niantong Recipe Based on lncRNA NEAT1 and Nrf2/ARE Pathway by FU Changlong, XIE Xinyu, QIU Zhiwei, HUANG Yanfeng, JIN Linglu, LI Xihai

“…ObjectiveTo evaluate the effect of Rongjin Niantong Recipe on knee osteoarthritis model rats, and to explore the mechanism of delaying cartilage degeneration in knee osteoarthritis based on long noncoding RNA (lncRNA) NEAT1 and Nrf2/ARE pathway.MethodsAfter adaptive feeding for one week, a total of 45 SPF SD rats aged two months were randomly divided into blank group and sodium iodoacetate group, with 15,30 cases in each group. …”
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Effects of L-carnitine supplementation in uremic patients receiving hemodialysis (尿毒症血液透析患者应用左卡尼汀临床效果观察) by YOU Huiqin (尤惠琴)

“…Objective To investigate the effects of L-carnitine supplementation in uremic patients receiving hemodialysis. Methods Totally100 uremic patients undergoing hemodialysis were randomly divided into the control group and observation group according to the random number table, with 50 cases in each group. …”
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Characteristics of Static Balance Function in Elderly Patients with Type 2 Diabetes Mellitus in Different Blood Pressure States by Shuai GUO, Zhizhen LIU, Jiawei QIN, Lianhua YIN, Jia HUANG, Jing TAO

“…Objective:To analyze the changes characteristics of static balance function in elderly patients with type 2 diabetes mellitus (T2DM) in different blood pressure states.Methods:A total of 2 179 medical records of eligible subjects who were selected for physical examination in the Second People's Hospital of Fujian University of Traditional Chinese Medicine from November 2013 to August 2020, which were divided into health people (the control group), the type 2 diabetes mellitus group under normal blood pressure state (T2DM group), the type 2 diabetes mellitus group under hypertension state (T2DM-HTN group) according to the state of blood pressure and blood sugar status, with 281 cases in the control group by the propensity score matching method, with 273 cases and 281 cases respectively in the T2DM group and the T2DM-HTN group. …”
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Effect of optimizing the nursing process of green channel on time course of intravenous thrombolysis for acute ischemic stroke (优化绿色通道护理流程对急诊缺血性脑卒中静脉溶栓时间节点的影响)... by PENG Hong (彭红), LIU Ruihua (刘瑞华), LI Xue (李雪), ZHAN Qian (张倩)

“…Objective To investigate the effect of optimizing the nursing process of green channel on time course of intravenous thrombolysis for acute ischemic stroke (AIS). Methods Totally 99 AIS patients who received intravenous thrombolysis were divided into two groups according to the according to date of hospital admission: 41 cases who received intravenous thrombolysis before implementation of optimized nursing process of green channel (between November 2020 and March 2021) were included as the control group, 48 cases who received intravenous thrombolysis after implementation of optimized nursing process of green channel (between April 2021 and October 2021) were included as the observation group. …”
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Effect of breathing exercises combined with behavioral intervention in nursing of patients with asthma (呼吸训练联合行为干预在哮喘患者护理中的应用效果观察) by TIAN Shuijing (田水静), ZHANG Wenzheng (张文峥), WANG Yan (王燕)

“…Objective To investigate the effect of breathing exercises combined with behavioral intervention in nursing of patients with asthma patients, and provide reference for the nursing quality improvement. Methods Totally 90 cases of asthma patients admitted to the hospital from May 2021 to February 2023 were selected and divided into a control group and an observation group using a randomized numerical table method, with 45 cases in each group. …”
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