Genotype by environment interactions and phenotypic traits stability of the EUCLEG faba bean collection by Dejan Sokolović, Snežana Babić, Mirjana Petrović, Ignacio Solís, Mathias Cougnon, Natalia Gutierrez, Pertti Pärssinen, Dirk Reheul, Jasmina Radović, Ana M. Torres

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A qualitative research on health education needs of pregnant women with gestational diabetes mellitus (妊娠期糖尿病孕产妇健康教育需求的质性研究) by TAN Minjing (覃敏静), YANG Miaomiao (杨苗苗), WANG Kaihua (王凯华), LUO Chunmiao (罗春苗), ZHOU Jinchang (周金嫦)

“…The phenomenological research method in the qualitative research was used to conduct semi-structured interviews. …”
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Clinical Efficacy of Muscle Energy Technology Combined with Conventional Rehabilitation Therapy on Patients with Chronic Non-Specific Neck Pain by ZHENG Kun, YANG Haolun, JIA Chengsen, ZHANG Liming

“…ObjectiveTo observe the effects of muscle energy technology (MET) combined with conventional rehabilitation trerapy on patients with chronic non-specific neck pain (CNSNP).MethodsA total of 54 patients with CNSNP in the outpatient department of rehabilitation medical center of West China Hospital, Sichuan University from May 2022 to March 2023 were randomly divided into control group and observation group, with 27 cases in each group. …”
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Meta Analysis on Rehabilitation Effect of Proprioception Training on Ankle Sprainof Athletes by Yuxiao CHEN, Jiaojiao LIU, Changsong Yi, Mengguang CHAI, Qing WANG, Lei JIANG

“…Objective:To explore the effects of proprioception training on the incidence of athletes' ankle sprains, dynamic neuromuscular control, postural stability and joint position perception.Methods:Data were searched from the databases of PubMed, Cochrane Library, EMbase, China National Knowledge Infrastructure(CNKI), Wanfang Database(Wangfang Data), Chinese Journal Full-text Database(VIP), China Biomedical Literature Database(CBMdisc).Athletes were included in the randomized controlled trials(RCTs)who were treated with proprioception training to improve the function of athlete's ankle joint.The retrieval time for each database was from the establishment of the database to December 31, 2019, and the references of related documents were traced.Two researchers independently searchered the literature, extracted data, and evaluated the quality of the literature.RevMan5.3 software was used to analyze the data.According to the systematic review manual provided by the Cochrane Collaboration Network, the continuous variables use mean difference(<italic>MD</italic>)and 95%confidence interval(<italic>CI</italic>)as indicators, and binary variables use risk ratio(RR)and 95%<italic>CI</italic> as indicators.The statistical heterogeneity was judged comprehensively by chi-square test(χ²test)and the Heterogeneity test(<italic>I</italic>²test).If <italic>P</italic>≥0.1 and <italic>I</italic>²≤50%, a fixed effects model would be used.In contrast, if <italic>P</italic>&lt;0.1 or <italic>I</italic>²&gt;50%, a random effects model would be used.Results:A total of 11 RCTs and 1 776 athletes were included.The results of Meta analysis showed that compared with the control group, the incidence of ankle sprains in the experimental group was significantly reduced after proprioceptive training[<italic>RR</italic>=0.61, 95%<italic>CI</italic>(0.41, 0.90), <italic>P</italic>=0.01]; compared with the control group, the posterolateral and posterior medical maximum extension distances of the experimental group increased significantly after proprioception training[<italic>MD</italic>=4.44, 95%<italic>CI</italic>(3.66, 5.23), <italic>P</italic>&lt;0.00 001;<italic>MD</italic>=4.21, 95%<italic>CI</italic>(3.18, 5.24), <italic>P</italic>&lt;0.00 001]and the difference was statistically significant;but there was no significant difference in the improvement effect of the anterior maximum extension distance, and the difference was not statistically significant(<italic>P</italic>&gt;0.05).The postural sway of the affected ankle joint in the experimental group was significantly lower than that in the control group;the athletes in the experimental group had better position perception ability in the ankle joint plantar flexion, dorsiflexion, middle and lateral directions than the control group.Conclusion:Proprioceptive training can effectively reduce the incidence of athletes' ankle sprains, improve dynamic neuromuscular control, improve postural stability, and enhance ankle joint position perception, which is worthy of clinical application.However, the absolute effect is not yet clear, so large samples and high-quality randomized controlled trials are still needed to further verify the efficacy of proprioception training, so as to provide more reliable evidence-based evidence for clinical rehabilitation.…”
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Application of “One Syndrome and One Product”nursing mode for inpatients with post-stroke depression (“一证一品”护理模式在中风后抑郁患者护理中的应用) by YANG Yu (杨宇), WANG Xuesong (王雪送), FAN Yan (范艳), LIU Yanna (刘燕娜), HU Shirong (胡世荣)

“…Objective To explore the application of “One Syndrome and One Product” in care of post-stroke depression. Methods Totally 90 inpatients of post-stroke depression were divided into control (n=45)and observation group (n=45) according on randomized principles. …”
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Application of continuous improvement process in reducing the return-cleaning rate of lumen surgical instruments (质量持续改进活动在降低手术管腔器械清洗返洗率中的应用)... by JIANG Linghua (蒋玲华), LI Shaoping (李绍平), YAO Shixiu (姚仕秀), YANG Weizao (杨伟造)

“…Objective To investigate the effect of continuous improvement process (CIP) in reducing the return-cleaning rate of lumen surgical instruments. Methods A CIP group was set up, and theme and plan of CIP activities were identified. …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca²⁺concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic>&lt;0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic>&lt;0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic>&lt;0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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圈养小熊猫育幼期行为对幼仔成活率的影响 by 韦华 # 何胜山 # 吴代福刘晓强肖仁莉邓鑫怡杨洪杨建

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Meta Analysis of Clinical Efficacy of Traditional Chinese Medicine Compounds of Huoxue Yangyin in the Treatment of Vocal Cord Polyp after Surgery by GE Xiaoni, ZHU Ling, SONG Ruohui, TU Yanhong, ZHENG Rixin

“…ObjectiveTo evaluate the clinical efficacy and safety of the traditional Chinese medicine compounds "Huoxue Yangyin" for promoting blood circulation and nourishing Yin in the treatment of postoperative discomfort of vocal cord polyp by Metaanalysis.MethodsData were searched from the databases of China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP) ,Wanfang Database (Wanfang Data), China Biomedical Literature Database, PubMed, Embase, Web of science,Springer and Cochrane Library,etc. …”
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越冬期不同水位环境下青头潜鸭行为模式比较 by 肖超, 宋曦濂, 邓文攸, 孙雪莹, 吕泓学, 吴庆明, 马兆春

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Clinical Effects of Smart Phone Speech Training Combined with Scalp Acupuncture in Patients with Non-fluent Aphasia after Stroke by Mingyue XIONG, Yanyan TANG, Lihua CAO, Dian HUANG, Xiaodan LI, Jie TAN

“…Objective:To observe the clinical effect of smart phone speech training combined with scalp acupuncture in patients with non-fluent aphasia after stroke, in order to explore a suitable combination of traditional Chinese and western medicine therapy for aphasia.Methods:A total of 40 patients with non-fluent aphasia after stroke were randomly divided into treatment group and control group, with 20 cases in each group. …”
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Effect of Exercise Preconditioning on Protein Expression of VEGF and NeuN in Rats with Cerebral Ischemia-reperfusion by Fei PEI, Xuedong WANG, Baolong LI, Qiang TANG, Luwen ZHU

“…Objective:To explore the effects of exercise preconditioning on the expression of vascular endothelial growth factor (VEGF) and neuronal core antigen (NeuN) proteins in rats with cerebral ischemia-reperfusion.Methods:The rats were randomly divided into sham-operation group, model group, exercise sham-operation group (exercise pretreatment and sham-operation group) and exercise model group (exercise pretreatment and model group) by the random number table method, with 24 rats in each group. …”
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Mechanism of Bushen Huoxue Recipe on Improving Arterial Calcification in Rats with Osteoporosis Based on OPG/RANKL Signaling Pathway by LIN Xiaorong, YANG Na, ZHENG Bei, ZHAO Hu, XU Junxia

“…ObjectiveTo observe the effect of Bushen Huoxue Recipe on thoracic aortic calcification and explore the possible mechanism of improving arterial calcification by Bushen Huoxue Recipe based on osteoprotegerin / receptor activator for nuclear factor-κB ligand (OPG/RANKL) signaling pathway in rat model of osteoporosis.MethodsA total of 32 seven-month-old male SD rats were randomly divided into control group, sham operation group, osteoporosis group and Bushen Huoxue group, with eight rats in each group. …”
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Effect of Repetitive Transcranial Magnetic Stimulation Combined with Exercise Therapy on the Motor Function in Stroke Patients with Hemiplegia by Wani ZHOU, Lei ZHANG, Rundong LI, Kaiquan XU, Chengji WU

“…Objective:To discuss the effect of repetitive transcranial magnetic stimulation (rTMS) combined with exercise therapy on the motor function in stroke patients with hemiplegia.Methods:A total of 100 stroke patients with hemiplegia were selected from September 2016 to September 2018, according to the random number table, and they were divided into excitation group and exercise group, with 50 cases in each group. …”
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Risk factors of aspiration in neurocritical care patients with enteral nutrition (神经重症肠内营养支持患者误吸危险因素分析) by WANG Dan (王丹), KUANG Hongmei (况红梅), LIU Weichen (刘韦辰)

“…Objective To analyze the influencing factors of aspiration in neurocritical care patients with enteral nutrition, and to provide a reference for formulating strategies to prevent the incidence of aspiration. Methods From July 2020 to July 2021, 527 neurocritical care patients with enteral nutrition in a tertiary hospital in Jiangxi Province were selected, and they were divided into aspiration group and non-aspiration group according to whether aspiration occurred. …”
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Investigation and analysis on the status quo of nurses' knowledge of urinary incontinence and their training needs in the region (上海市某区域护士尿失禁知识认知现状与培训需求的调查分析)... by YUAN Hongyan (袁红艳), XU Fanglei (许方蕾), TANG Ailing (汤爱玲), GE Yan (葛颜), DONG Li (董里)

“…Objective To understand the status quo of clinical nurses' cognition of urinary incontinence knowledge and the demand for specialized training of urinary incontinence in medical institutions at all levels in a certain region in Shanghai. Methods A questionnaire was designed based on the literature method, and a total of 384 clinical nurses were selected from 2 tertiary hospitals, 2 secondary hospitals and 4 community health service centers in a district of Shanghai by cluster sampling method. …”
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Effect of Robot-Assisted Gait Training on Lower Limb Motor Function of Children with Cerebral Palsy： A Meta-Analysis by JIANG Xiaoyu, BI Hongyan, SUN Wenyu, LIU Huifen, SU Hang, JIANG Jiahui

“…ObjectiveTo evaluate the effect of robot-assisted gait training (RAGT) on lower limb motor function of children with cerebral palsy (CP) by meta-analysis.MethodsData were searched from the Cochrane Library, PubMed, Web of Science, Embase, CNKI, Wanfang Data, VIP and CBMdisc databases. …”
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Application of acupuncture therapy combined with Traditional Chinese Medicine nursing for patients with postherpetic neuralgia (针灸治疗联合中医护理在带状疱疹后神经疼痛患者中的应用)... by ZHOU Xu (周旭), LIU Xuan (刘璇)

“…Objective To explore the application effect of acupuncture combined with Traditional Chinese Medicine (TCM) nursing for patients with postherpetic neuralgia (PHN). Methods A total of 124 PHN patients were randomly divided into two groups, with 62 cases in each group. …”
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Application of case-based learning combined with problem-based learning in standardized training of cerebrospinal fluid drainage (CBL结合PBL教学模式在脑脊液外引流规范化培训中的应用)... by YIN Yating (殷亚婷), ZHEN Qin (郑琴), LIU Fang (刘芳), CHEN Lishan (陈丽珊), XUE Qiang (薛强)

“…The conventional teaching model was adopted in the control group, while a combined teaching methods of CBL and PBL was used in the study group. …”
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A qualitative study on professional cognition and emotion of nursing students based on visual thinking theory (基于视觉思维理论的影视、听资料对护理学生专业认知和情感影响的质性研究)... by BAI Jinlu (白金璐), LI Chunxiang (李春香), XU Hang (许航), LI Yan (李妍)

“…Methods The phenomenological method was used to conduct in-depth interviews with 14 nursing students in the school of Nursing of Henan University of science and Technology, and the data were analyzed by Colaizzi's 7-step method analysis method. …”
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