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53321
Effect and Mechanism of Catalpol on Behavior in Rats with Post-stroke Depression
Published 2022-02-01“…ObjectiveTo explore the effect of catalpol on the behavior of post-stroke depression rats, and to explore its mechanism from the aspects of behavior, the expression of 5-hydroxytryptamine (5-HT), norepinephrine (NE) and brain-derived neurotrophic factor (BDNF) in peripheral serum and brain tissue.MethodsA total of twenty-four SD rats were randomly divided into model group, catalpol intervention group and sham operation group, with 8 rats in each group. …”
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53322
A qualitative study on the motivations to bariatric surgery of patients with obesity (肥胖症患者寻求减重手术动机的质性研究)
Published 2021-06-01“…Objective To understand the feelings and to explore the motivations of domestic obese people undergoing bariatric surgery. Methods Phenomenological research design and semi-structural interviews were conducted on 15 obesity patients who undergoing bariatric surgery, and the collected data were analyzed with the method of Colaizzi Phenomenological analysis. …”
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53325
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53326
Anti-HEV antibody reactivity rate in voluntary blood donors in China: a Meta-analysis
Published 2025-01-01“…Based on different age grouping methods, they were divided into two groups. The age groups of group A were divided into ≤ 20 years old, 21-30 years old, 31-40 years old, 41-50 years old and >50 years old. …”
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53327
Application of comprehensive nursing in the treatment of chronic constipation with fecal microbiota transplantation (综合护理在粪菌移植治疗慢性便秘中的应用)
Published 2021-11-01“…Objective To observe and analyze the clinical effect of comprehensive nursing interventions in the treatment of chronic constipation with fecal microbiota transplantation. Methods In this study, 46 patients with chronic constipation who received fecal microbiota transplantation were selected as the research object, and were randomly divided into observation group and control group, with 23 cases in each group. …”
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53328
Identification of the RHD novel allele c. 801+2T>G and study of its effect on RhD phenotype in vitro
Published 2024-12-01“…[Objective] To further identify the RhD phenotype and RHD genotype in the individual who have RhD negative phenotype in the primary screening, and to analyze the effect of c. 801+2T>G mutation on RhD phenotype by minigene splicing assay. [Methods] The serologic test was performed for RhD phenotype identification and absorption-elution test was performed by using monoclonal anti-D. …”
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53329
Optimizing strategy for training of home blood pressure monitoring in hypertension patients (优化家庭血压测量技术培训在高血压患者健康教育中的应用)
Published 2021-05-01“…Objective To investigate the effect of optimized strategy for training of home blood pressure monitoring in hypertension patients. Methods Totally 120 hypertension patients were divided into two group according to the admission time: 60 patients recruited from October 2019 to May 2020 were set as control group, another 60 patients recruited from June 2020 to October 2020 were set as observation group. …”
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53330
Relationship between core competence and professional identity among critical care nurses (急危重症护士核心能力与职业认同感相关性研究)
Published 2024-10-01“…Objective To investigate the current condition and relationship of core competence and professional identity among critical care nurses in Guangyuan city, Sichuan Province, and provide reference for advanced skill training and management of critical care nurses. Methods The Competency Inventory For Registered Nurse and Professional Identification Scale were used to investigate 175 critical care nurses in Guangyuan city, Sichuan Province. …”
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53331
Effect on Balance Function in Patients with Parkinson's Disease Treated by Transcranial Direct Current Stimulation
Published 2019-06-01“…Objective:To observe the improvement of balance function in patients with Parkinson's disease treated by transcranial direct current stimulation(tDCS).Methods:With double-blind, random and control studies, using the random number generator in SPSS 20.0 statistical software, a total of 49 patients with Parkinson's disease who met the inclusion criteria were divided into intervention group(<italic>n</italic>=25)and control group(<italic>n</italic>=24).In addition to the routine treatment, both of groups were given the treatment of tDCS respectively. …”
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53332
Montmorillonite powder combined with liquid dressing and nursing management for a patient with bacterial pneumonia complicated by perianal incontinence dermatitis (1例细菌性肺炎并发肛周失禁性皮炎...
Published 2023-03-01“…The patient was treated with Montmorillonite powder combined with liquid dressing. on the basis of routine perianal care, the dressing exchange method was improved, and the individualized scheme of Montmorillonite powder combined with liquid dressing was adopted. …”
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53333
Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology
Published 2020-12-01“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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53335
Case Report of Jingyun Platform's Cognitive Training on Cognitive Impairment with Aphasia
Published 2019-08-01“…Objective:To observe the curative effect of Jingyun platform's cognitive training on cognitive impairment with aphasia.Methods:A case of cognitive impairment with aphasia was collected, and ABBA model was used to design a case in-subject. …”
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53336
Effect of Xingnao Kaiqiao Acupuncture combined with EEG Biomimetic Electrical Stimulation on Evoked Potential of Patients with Persistent Vegetative State
Published 2020-04-01“…Objective:To observe the effect of Xingnao Kaiqiao acupuncture combined with EEG biomimetic electrical stimulation on brainstem auditory evoked potential (BEAP) and somatosensory evoked potential (SEP) in patients with persistent vegetative state (PVS).Methods:A total of ninety patients with PVS treated in the PVS awareness center of Guangdong 999 Brain hospital were randomly divided into Acupuncture group, Bionic electricity group and Combined group, with thirty cases in each group. …”
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53337
Effect of Stroke Unit Nursing Mode on the Prognosis of Patients with Ischemic Stroke
Published 2020-04-01“…Objective:To observe the effect of stroke unit nursing on the prognosis of patients with ischemic stroke.Methods:A total of 216 patients with ischemic stroke which were treated in the first affiliated hospital of Harbin Medical University were randomly divided to the control group and observation group, with 108 patients in each group. …”
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Investigation and cause analysis of out-patient experience based on brand recognition model (基于品牌认知模型的门诊就诊患者体验调查与原因分析)
Published 2023-06-01“…Objective By studying the relationship between outpatient experience and satisfaction, loyalty, and recommendation, find out the current factors affecting the medical experience of outpatient, and improve the overall service quality of the hospital. Methods Using indicators of Outpatient Experience Questionnaire (OPEQ), Patient Experience With Medical care (PEES-50) and other questionnaires, a model of the relationship between patient experience and satisfaction, loyalty, and recommendation was built, and expected satisfaction degree was considered as an intermediary variable to study the interaction between model variables. …”
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53340
Effect of Graphene Warm Abduction Orthosis on Hip Joint Development in Children with Spastic Cerebral Palsy
Published 2023-10-01“…ObjectiveTo observe the effect of graphene warm abduction orthosis on hip joint development in children with spastic cerebral palsy.MethodsA total of 28 children (56 hips) aged 2-10 years with spastic cerebral palsy were randomly divided into two groups by random number table method. …”
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