Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users by Jessica A. Wright, Linda Huang, Basant E. Katamesh, Siddhant Yadav, Abhinav Singla, Ann Vincent

“…Conclusion The results this study reveal the spectrum of hypothesized alterations in THC and CBD metabolism due to atypical genetic variants and medications. …”
Get full text

Development, validation, and usage of metrics to evaluate the quality of clinical research hypotheses by Xia Jing, Yuchun Zhou, James J. Cimino, Jay H. Shubrook, Vimla L. Patel, Sonsoles De Lacalle, Aneesa Weaver, Chang Liu

Get full text

Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients by Kristen M. Drescher, Poonam Sharma, Henry T. Lynch

Get full text

Investigations sur une crise de mortalité à Boulogne-sur-Mer (Pas-de-Calais, XVIIIe s.). Hypothèses d’interprétation by Dominique Castex, Hélène Réveillas

“…Historical, archaeological and anthropological arguments rule out the hypotheses of war or famine as the cause of this peak, leaving that of an epidemic. …”
Get full text

Imagining the monstrous other: An introduction to the research on the medicalized undead by Mandić Marina

“…This paper serves as an introduction to various perspectives on monstrous Others and the medicalization of the undead (mainly zombies). It aims to formulate initial hypotheses for researching the impacts of disease, death, and monstrous transformation, including bodily, identity, and cognitive characteristics that determine and redefine our understanding of monstrosity and humanity.…”
Get full text

Influence of Medication on Fatigue Six Months after Stroke by Amélie Ponchel, Julien Labreuche, Stéphanie Bombois, Christine Delmaire, Régis Bordet, Hilde Hénon

“…Poststroke fatigue (PSF) is frequent and affects patients’ quality of life. Medication use was hypothesized as being responsible for PSF. …”
Get full text

Development and validation of the “Adjustment Disorder Scale for Medically Ill Patients - ETAM” by Juan Pablo Zapata-Ospina, Natalia Rodríguez, Ayda Margarita Rodríguez, Jenny García-Valencia, Mercedes Jiménez-Benítez, Nicolás Martínez-Ramos, Diana Restrepo Bernal, Ana Lucía Gallego, Carolina Gómez, Luis Fernando Tabares, Carlos Cardeño-Castro, Daniel Camilo Aguirre-Acevedo

“…BackgroundAdjustment disorder (AD) is common among medically ill patients, yet current evaluation methods do not address the specific characteristics in this population. …”
Get full text

The Effects of Catheter Ablation Therapy on Medication Use and Expenditures in Patients with Atrial Fibrillation by Matthew R. Reynolds, Guy David, Candace Gunnarsson, Jamie L. March, Steven C. Hao

“…Catheter ablation has been hypothesized to reduce the need for continued medical therapy for patients with AF, but there are few empirical data which demonstrate this. …”
Get full text

Impact of care guilt on the health status of female medical staff: a cross-sectional study by Jia Xu, Chun Xia

“…Abstract Background In this study, we explored changes to female medical staff’s health status under the influence of care guilt in the process of balancing work and family care responsibilities. …”
Get full text

Enhancing Spatial Allocation of Pediatric Medical Facilities for Reduced Travel-Related CO₂ Emissions: A Case Study in Tianjin, China by Hongjie Dong, He Zhang, Rui Wang, Yutong Zhang, Yuxue Zhang, Lisha Zhang

“…It introduces a model for measuring travel-related CO₂ emissions for pediatric medical-seeking, STIRPAT, and ridge regression models as well as conducts simulations under various scenarios to test the hypotheses. …”
Get full text

An analysis of causal relationships among the factors affecting the academic performance of students at the Alborz University of Medical Sciences by Leili Salehi, Mandana Shirazi, Maryam Safarnavadeh, Zohreh Mahmoodi

“…The present study aimed at evaluating the mediating role of self-efficacy in the relationship between stress and effort–reward imbalance (E.R.I) and the students’ academic performance (AP) at the Alborz University of Medical Sciences. MATERIALS AND METHOD: This descriptive-analytical study of the structural equation type was conducted on the 530 students studying at Alborz University of Medical Sciences during 2021–2022. …”
Get full text

Writing case reports and series: Tricks, traps, and triumphs! by Abraham Edgar Gracia-Ramos

“…The case reports and case series are the oldest genres of medical literature. They constitute uncontrolled study designs with different varieties that describe important scientific observations that are missed or undetectable in other research methods. …”
Get full text

Progression of Left Ventricular Dysfunction and Remodelling under Optimal Medical Therapy in CHF Patients: Role of Individual Genetic Background by Marzia Rigolli, Mariantonietta Cicoira, Corinna Bergamini, Andrea Chiampan, Andrea Rossi, Corrado Vassanelli

Get full text

The role of Pharmaceutical Marketing in Prescribing Decisions in a Developing Country: A Comprehensive Study Exploiting Theory of Planned Behaviour by Mahmoud Al-Areefi, Mohamed Izham Mohamed Ibrahim, Abubakr Abdelraouf Alfadl

Get full text

Knowledge and Attitude about Basic Life Support and Emergency Medical Services amongst Healthcare Interns in University Hospitals: A Cross-Sectional Study by Shahabe A. Saquib, Hassan M. Al-Harthi, Anas A. Khoshhal, Adel A. Shaher, Abdulsalam B. Al-Shammari, AbdulAhad Khan, Tahani A. Al-Qahtani, Imran Khalid

“…A self-explanatory questionnaire, comprising of 15 questions, was designed for the study. All the hypotheses were formulated using two-tailed alternatives against each null hypothesis. …”
Get full text

Lifetime history of concussion among children and adolescents with attention-deficit/hyperactivity disorder: examining differences stratified by age, medication status, and parent-... by Julia E. Maietta, Julia E. Maietta, Julia E. Maietta, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Nathan E. Cook, Nathan E. Cook, Nathan E. Cook, Nathan E. Cook

“…Contrary to our hypotheses among youth with ADHD, parent-reported ADHD severity and current medication status were not associated with lifetime concussion history.…”
Get full text

Self-reported health profiles of trauma victims with and without psychiatric histories by Alan R. King, Sara K. Kuhn, Stephanie Brezinski, Michael Jowkar, Kourtney Smith

“…Results Support was found for all three hypotheses: (H1) Self-identified trauma was associated with higher prevalence rates for 16 of 18 medical diagnoses; (H2) PTSD diagnoses were associated with higher prevalence rates than trauma alone for 6 of 16 medical conditions; and (H3) Self-reported trauma was associated with higher prevalence rates for 7 of 18 medical condi-tions among respondents who denied psychiatric histories. …”
Get full text

Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models by Jamie L. Lim, Stine Marie Jensen, Jaap J. Plomp, Bernhardt Vankerckhoven, Christa Kneip, Rani Coppejans, Christophe Steyaert, Kathleen Moens, Lieselot De Clercq, Martijn R. Tannemaat, Peter Ulrichts, Karen Silence, Silvère M. van der Maarel, Dana L.E. Vergoossen, Roeland Vanhauwaert, Jan J. Verschuuren, Maartje G. Huijbers

Get full text

Artificial neural networks analysis predicts long-term fistula function in hemodialysis patients following percutaneous transluminal angioplasty by Aichi Chien, Ayush Lall, Maitraya Patel, Lucas Cusumano, Justin McWilliams

“…Therefore, in this paper we hypothesize that based on patient-specific information collected during PTA, a predictive model can be created to help improve treatment planning. …”
Get full text

A Pharmacotherapy and ECT resistant OCD patient’s Cognitive Behavioral Therapy by Tacettin KURU, M. Hakan TÜRKÇAPAR

Get full text