Safety and efficacy of oral cancer vaccine B440 in patients with PD-1/PD-L1 inhibitor-resistant advanced urothelial cancer: a study protocol for a phase 1 multicenter, open-label,... by Junya Furukawa, Yasumasa Kakei, Sae Murakami, Hiroshi Kita, Hideto Ueki, Takuto Hara, Jun Teishima, Nobuyuki Hinata, Hideaki Miyake, Masato Fujisawa, Toshiro Shirakawa

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Lower Dose of 5 mL of 1% Lidocaine is More Suitable than the Conventional 10 mL for Caudal Block in Transrectal Prostate Biopsy: A Retrospective Cohort Study by Norichika Ueda, Mototaka Sato, Shunsuke Mori, Atsuki Matsukawa, Yuta Oki, Yuma Kujime, Ryoya Mizuno, Hiromu Horitani, Tetsuya Yamamoto, Shota Fukae, Mitsuhiro Yoshinaga, Makoto Matsushita, Mai Akiyama, Satoshi Kamido, Ayako Honda, Jiro Nakayama, Norihide Tei, Osamu Miyake

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Sequential Serous Choroidal Detachment in Subjects Undergoing Bilateral Trabeculectomy by Maryam Yadgari, Kiana Hassanpour, Fatemeh Vafaei, Nina Firoozian, Maryam Oraee Yazdani, Zahra Khorram, Sadid Hooshmandi

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Surgical Challenges in Multi-Vessel Minimally Invasive Coronary Artery Bypass Grafting by Jia-Ji Liu, Qing-Yu Kong, Bin You, Lin Liang, Wei Xiao, Xiao-long Ma, Feng Pan, Li-Qun Chi

“…Surgical challenges encountered during this procedure may increase the operative duration, intraoperative blood loss, ICU admission, and the duration of postoperative hospitalization. …”
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Risk Factors for Shoulder Injuries in Water Polo: a Cohort Study by Félix Croteau, David Paradelo, David Pearsall, Shawn Robbins

“… # Conclusions Previous injury, changes in IR ROM and UR are related to new shoulder injuries in water polo, but further variables such as rest, training load, or psychosocial factors may explain the incidence of new injuries. # Level of Evidence Level 3…”
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Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine by Fekri Samarah, Mahmoud A. Srour, Dirgham Yaseen, Kamal Dumaidi

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Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study by Yunyi Yan, Nozomi Kondo, Kentaro Oniki, Hiroshi Watanabe, Tadashi Imafuku, Yuki Sakamoto, Takuro Shigaki, Akari Maruyama, Hitomi Nakazawa, Tetsuya Kaneko, Ayami Morita, Akira Yoshida, Hitoshi Maeda, Toru Maruyama, Hideaki Jinnouchi, Junji Saruwatari

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Indications and Current Surgical Techniques for Keratoplasty: A 10-year Review from 2011 through 2020 at a Tertiary Referral Hospital in Thailand by Wipawee Booranapong, Chayanit Junsangsri, Chareenun Chirapapaisan, Panotsom Ngowyutagon, Sathiya Kengpunpanich

“…The use of PKP decreased from 96.0% to 86.7%; however, EK increased from 1.5% to 8.9%, while DALK rose slightly from 2.5% to 4.4%. …”
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A comprehensive analysis of percutaneous liver biopsy characteristics and pathological manifestations in a large patient cohort (2009–2024) by Minling Cao, Jiayi Zeng, Jiayu Wang, Junmin Jiang

“…Conclusion This study offers a comprehensive analysis of the characteristics and pathological manifestations of patients who underwent percutaneous liver biopsies over a 15-year period. The findings underscore the varying pathological manifestations across different age groups for the four major liver diseases and emphasize the necessity for tailored therapeutic interventions, particularly for patients with concurrent hepatitis B and MASLD, as antiviral therapy alone may be inadequate. …”
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Computational and experimental approaches to explore defense related enzymes conferring resistance in Fusarium infected chilli plants by regulating plant metabolism through nutriti... by Muhammad Usman, Muhammad Atiq, Nasir Ahmed Rajput, Muhammad Sagheer, Ye Xia

“…Results indicated that the combination of Krystafeed and Micro Plus was found the most effective with (27.01, 26.59%) disease incidence, followed by Micro Plus (29.56, 32.35%) and Krystafeed (38.21, 41.15%), both in greenhouse and field conditions, respectively. …”
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Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…The mean IOP of 16.3±2.1 mm Hg before SLT decreased by 17.1%±9.5% to 13.4±1.9 mm Hg at 12 months after SLT in the first-line group (p<0.001), and the mean IOP of 15.4±1.5 mm Hg before SLT decreased by 12.7%±9.7% to 13.2±2.0 mm Hg at 12 months after SLT (p=0.005) in the second-line group. …”
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Modifiable Risk Factors Including Self-Perceived Stress for Breast Cancer in Hong Kong: A Case-Control Study of 10 757 Subject by Winnie Yeo, Lok-Wa Yuen, Kelvin Kam-Fai Tsoi, Emily Ying-Yang Chan, Carol C Kwok, Inda Soong, Ting-Ying Ng, Joanne Chiu, Miranda Chan, Sharon Wing-Wai Chan, Ting-Ting Wong, Yolanda Ho-Yan Chan, Lawrence Pui-Ki Li, Chun-Chung Yau, Wai-Ka Hung, Polly Suk-Yee Cheung

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Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium by V. A. Ivanisenko, N. V. Basov, A. A. Makarova, A. S. Venzel, A. D. Rogachev, P. S. Demenkov, T.  V. Ivanisenko, M. A. Kleshchev, E. V. Gaisler, G. B. Moroz, V. V. Plesko, Y. S. Sotnikova, Y. V. Patrushev, V. V. Lomivorotov, N. A. Kolchanov, A. G. Pokrovsky

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A systematic review of the worldwide prevalence of survivors of poliomyelitis reported in 31 studies by Alice Theadom, Shivanthi Balalla, Kelly M Jones, Valery L Feigin, Gordon Jackman

“…Significant variability in the prevalence of survivors of poliomyelitis was revealed, in low- income to lower middle-income (15 per 100 000 in Nigeria to 1733 in India) and upper-middle to high-income countries (24 (Japan) to 380 per 100 000 (Brazil). …”
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Impact of Resuscitated Cardiac Arrest in the Brain-dead Donors on the Outcome of Liver Transplantation: A Retrospective and Propensity Score Matching Analysis by Shengmin Mei, MD, Jie Xiang, MD, Li Wang, MD, Yuan Xu, MD, Zhiwei Li, MD

“…The CA group demonstrated shorter hospital stay (15.5 ± 20.0 days vs. 16.2 ± 21.3 days, P = 0.041), with comparable incidence of early graft failure (EGF, 5.8% vs. 6.2%, P = 0.161). …”
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Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study by Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li, Zeyu Wang

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Dilated cardiomyopathy signature metabolic marker screening: Machine learning and multi-omics analysis by Xiao-Lei Li, Aibibanmu Aizezi, Yan-Peng Li, Yan-Hong Li, Fen Liu, Qian Zhao, Xiang Ma, Dilare Adi, Yi-Tong Ma

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Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache by Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

“…Moreover, a significant minority of patients with orthostatic headache may paradoxically have a high CSF pressure state, which can be detected using ICP monitoring. …”
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Perbandingan Insidensi Hipotensi Saat Induksi Intravena Propofol 2 Mg/Kg Bb Pada Posisi Supine dengan Perlakuan dan Tanpa Perlakuan Elevasi Tungkai by Beni Indra, Untung Widodo, Yunita Widyastuti

“…In the third minute, incidence of hypotension was also significantly lower in group A (15,2%) than group B (23,9%), p value = 0,014 (p < 0,05). …”
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Vonoprazan-Based Regimen Is More Useful than PPI-Based One as a First-Line Helicobacter pylori Eradication: A Randomized Controlled Trial by Masafumi Maruyama, Naoki Tanaka, Daisuke Kubota, Masayuki Miyajima, Takefumi Kimura, Koujiro Tokutake, Ryujiro Imai, Toru Fujisawa, Hiromitsu Mori, Yoshiaki Matsuda, Shuichi Wada, Akira Horiuchi, Kendo Kiyosawa

“…The eradication rate was significantly higher in VPZ group than PPI group by intention-to-treat analysis (95.8% versus 69.6%, P=0.00003, 95% confidence interval [CI] 88.3-99.1% versus 57.3-80.1%) and per-protocol analysis (95.7% versus 71.4%, P=0.0002, 95% CI 88.0-99.1% versus 58.7-82.1%). The incidence of adverse events was not different between the groups (26.3% in VPZ group versus 37.7% in PPI group, P=0.15). …”
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