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    A novel Alteromonas phage with tail fiber containing six potential iron-binding domains by Chen Yu, Meishun Yu, Ruijie Ma, Shuzhen Wei, Min Jin, Nianzhi Jiao, Qiang Zheng, Rui Zhang, Xuejin Feng

    Published 2025-01-01
    “…Remarkably, the prediction of the R22Y tail fiber structure revealed six conserved histidine residues (HxH motifs) that could potentially bind iron ions, suggesting that alterophages may function as organic iron-binding ligands in the marine environment. Our isolation and characterization of R22Y complements the Trojan Horse hypothesis, proposes the possible role of alterophages for marine iron biogeochemical cycling, and provides new insights into phage-host interactions in the iron-limited ocean.IMPORTANCEIron (Fe), as an essential micronutrient, is often a limiting factor for microbial growth in marine ecosystems. …”
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