29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset... by Ming Liu, Keman Xu, Fatma Saaoud, Ying Shao, Ruijing Zhang, Yifan Lu, Yu Sun, Charles Drummer, Li Li, Sheng Wu, Satya P. Kunapuli, Gerard J. Criner, Jianxin Sun, Huimin Shan, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a database mining on 102 transcriptomic datasets for the expressions of 29 m6A-RNA methylation (epitranscriptomic) regulators (m6A-RMRs) in 41 diseases and cancers and made significant findings: (1) a few m6A-RMRs were upregulated; and most m6A-RMRs were downregulated in sepsis, acute respiratory distress syndrome, shock, and trauma; (2) half of 29 m6A-RMRs were downregulated in atherosclerosis; (3) inflammatory bowel disease and rheumatoid arthritis modulated m6A-RMRs more than lupus and psoriasis; (4) some organ failures shared eight upregulated m6A-RMRs; end-stage renal failure (ESRF) downregulated 85% of m6A-RMRs; (5) Middle-East respiratory syndrome coronavirus infections modulated m6A-RMRs the most among viral infections; (6) proinflammatory oxPAPC modulated m6A-RMRs more than DAMP stimulation including LPS and oxLDL; (7) upregulated m6A-RMRs were more than downregulated m6A-RMRs in cancer types; five types of cancers upregulated ≥10 m6A-RMRs; (8) proinflammatory M1 macrophages upregulated seven m6A-RMRs; (9) 86% of m6A-RMRs were differentially expressed in the six clusters of CD4+Foxp3+ immunosuppressive Treg, and 8 out of 12 Treg signatures regulated m6A-RMRs; (10) immune checkpoint receptors TIM3, TIGIT, PD-L2, and CTLA4 modulated m6A-RMRs, and inhibition of CD40 upregulated m6A-RMRs; (11) cytokines and interferons modulated m6A-RMRs; (12) NF-κB and JAK/STAT pathways upregulated more than downregulated m6A-RMRs whereas TP53, PTEN, and APC did the opposite; (13) methionine-homocysteine-methyl cycle enzyme Mthfd1 downregulated more than upregulated m6A-RMRs; (14) m6A writer RBM15 and one m6A eraser FTO, H3K4 methyltransferase MLL1, and DNA methyltransferase, DNMT1, regulated m6A-RMRs; and (15) 40 out of 165 ROS regulators were modulated by m6A eraser FTO and two m6A writers METTL3 and WTAP. …”
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Effect of Processed Coffee Husk on Feed Intake, Nutrient Digestibility, Body Weight Changes and Economic Feasibility of Bonga Sheep Fed on Natural Pasture Hay as a Basal Diet by Lidya Marew, Fentahun Meheret, Bimrew Asmare

“…The experimental treatment feeds include 400 g conventional concentrate mix (CM) containing Noug seed cake and wheat bran (T1); 200 g boiled coffee husk + 200 g CM (T2); 200 g roasted coffee husk + 200 g CM (T3) and 200 g raw coffee husk + 200 g CM (T4). The CM was made in the ratio of 1:1. The data collected from the 90‐day experimental period were: dry matter and nutrient intakes, initial body weight, final body weight and body weight changes. …”
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Identifikasi Tanaman Obat Indonesia Melalui Citra Daun Menggunakan Metode Convolutional Neural Network (CNN) by Budi Setiyono, Muhammad Riv’an Arif, Qonita Qurratu Aini, Theophil Henry Soegianto, Jasti Ohanna, Ricky Andrean Fernanda Gunawan, Ayu Putri Rizkia

“…The wide and varied varieties of medicinal plants make it difficult for the public to identify the types of Indonesian medicinal plants. …”
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Designing and modeling an intelligent system for managing the distribution and scheduling of farmed fish feed using the Arduino Uno microcontroller by Shayesteh Tabatabaei

“…The system operates by the Arduino board, utilizing pre-stored code, and making decisions based on predetermined time intervals between feeding sessions. …”
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Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering by Maria K. Jaakkola, Maria Rantala, Anna Jalo, Teemu Saari, Jaakko Hentilä, Jatta S. Helin, Tuuli A. Nissinen, Olli Eskola, Johan Rajander, Kirsi A. Virtanen, Jarna C. Hannukainen, Francisco López-Picón, Riku Klén

“…While GMM performed sufficiently, it was by far the slowest one among the tested approaches, making k-means combined with PCA the most promising candidate for further development. …”
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Innovative Model of Socio-Professional Development of a Student’s Personality by E. F. Zeer, V. S. Tretyakova, M. V. Zinnatova

“…The research materials can be useful to developers of educational programmes and training technologies of vocational education, to managers and specialists of educational organisations when making management decisions and organising the educational process.…”
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Wacana Gender Dalam Perjanjian Pernikahan Rifā'ah Rāfi’ Al-Ṭahṭāwī by Rangga Hafidin

“…At the phrase/sentence level, the study indicates that the sentence constructions made by Al-Ṭahṭāwī contribute to marginalizing the role of women in the presence of men. …”
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Exploring cooking fuel choices among Ghanaian women of reproductive age: A socio-economic analysis from a statistical mechanics perspective. by Richard Kwame Ansah, Richard Kena Boadi, William Obeng-Denteh, Killian Asampana Asosega, Kassim Tawiah

“…Financial support mechanisms like microfinance and subsidies, alongside reliable LPG infrastructure, can make access easier for these target groups. Tailored communication strategies, peer-to-peer learning, and collaboration with local institutions are crucial for spreading awareness and encouraging the adoption of LPG.…”
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EFEKTIVITAS PEMANFAATAN ALUN-ALUN SEBAGAI RUANG TERBUKA PUBLIK by Muhammad Uliah Shafar, Suzanna Ratih Sari

“…Through the sketches and symbols from the observations made in the morning and evening using the place center map method, user behavior was known to the facilities used in the Andi Makkasau square. …”
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Development of a Comprehensive Fall Risk Assessment Tool for Older People in Elderly Care Institutions and Its Test by LUO Yuan, ZHANG Hua, WANG Sanxiang, ZHANG Mengxi, DENG Yuqian, RAN Haiye, LIU Jiaxin, ZHANG Yi, CHEN Xi, WU Yibo, ZHAO Liping

“…Older people and nursing assistants in elderly care facilities were randomly selected to make a survey. SPSS 26.0 and AMOS 26.0 software were used to analyze and evaluate the reliability and validity of the assessment tool. …”
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Advertising in Lithuanian Periodicals in 1918-1940: Characteristics of its Quantitative and Qualitative Developement by Giedrė Polkaitė

“…Calculations of the data of adverts in periodicals in 1918-1940 were made, which allowed presenting the comparative analysis of quantitative parameters according to the nature of publications and their readers. …”
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Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…This study also aims to demonstrate how digital health technology can inform and improve mental health care delivery and policy making. MethodsThis retrospective, cross-sectional study used secondary data from SMARC on 10,033 psychiatric e-referrals in Saudi Arabia during 2020‐2021. …”
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Efek Electro Convulsive Therapy (ECT) terhadap Daya Ingat Pasien Skizofrenia di RSJ Prof. HB. Sa’anin Padang by Ikky Nabila Nandinanti, Yaslinda Yaunin, Siti Nurhajjah

“…Examination of memory using Memory Tests Indonesia is made the day before and 2 hours after ECT then the results are presented descriptively and analyzed by paired T test. …”
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Determining the Factors and Evolutionary Trends of Customer Engagement in Businesses: A Bibliometric Analysis by Reza Abbasi Mobarakabadi, Amir khanlari, Nader Seyyedamiri

“…From this perspective, organizations should delegate some control to the customer and provide them with incentives, effectively making the customer the marketer of the company. The second pathway has reached its peak with the emergence of social networks and interactions between organization-customer and customer-customer. …”
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Women's enrollment in community-based health insurance and its determinants in Sidama national regional state, Ethiopia, 2024: A multilevel analysis. by Kare Chawicha Debessa, Keneni Gutema Negeri, Mesay Hailu Dangisso

“…Investing in women's literacy and empowerment programs will enable them to make informed health choices, thereby increasing enrollment. …”
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Sistem Berbasis Private Blockchain sebagai Penyedia Layanan Autentikasi Publisher-Broker-Subscriber Pada Protokol Message Queue Telemetry Transport by Muhammad Naufal Dzakie, Adhitya Bhawiyuga, Achmad Basuki

“…Because of this the writer propose to make a smart contract that functions as an authentication server. …”
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Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…A marathon is often accompanied by an acute inflammatory response with transient immunosuppression, making runners susceptible to infections. Also, hormonal alterations such as increased cortisol levels or decreased testosterone levels immediately after a race are observed. …”
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Optimizing Talent Development for Goalkeepers: Psychological Characteristics, Stressors, and Sustainable Pathways in Elite Soccer by Camille Sabourin, Eric Terrien, Denis Ha

“…For instance, goalkeepers face unique challenges, including the need to maintain concentration despite fluctuations in activity, make split-second decisions under pressure, and manage stress during high-stakes moments (e.g., penalty shootouts; Otte et al., 2020; de Castro et al., 2021). …”
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins by Maria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, Iqbal Mahmud, Yue Lu, Ailing Huang, Lisa K. Duong, Qi Wang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Bo Wei, Wai-Kin Chan, Kevin Lin, Jie Zhang, Efrosini Tsouko, Shonik Ganjoo, Hampartsoum B. Barsoumian, Thomas S. Riad, Yun Hu, Carola Leuschner, Nahum Puebla-Osorio, Jing Wang, Jian Hu, Michael A. Davies, Vinay K. Puduvalli, Cyrielle Billon, Thomas P. Burris, Philip L. Lorenzi, Boyi Gan, James W. Welsh

“…This involves lipid peroxidation and enzymes like lysophosphatidylcholine acyltransferase 3 (Lpcat3), which makes cells more prone to ferroptosis. However, the mechanisms by which cancer cells avoid immunotherapy-mediated ferroptosis are unclear. …”
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Infestation and damage status assessment of white mango scale (Aulacaspis tubercularis) insect at boloso sore and boloso bombe districts of Wolaita Zone South Ethiopia by Andualem Alemayehu, Zerhun Tomas

“…Foliar Spraying of various botanical extracts such as Neem seed extract (Azadirachta indica). Several concoctions made from ash, soap and goat urine were mixed and sprayed on infested mango fruit leaves and twigs. …”
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