Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…Major Depressive Disorder (MDD) is a widespread psychiatric condition impacting social and occupational functioning, making it a leading cause of disability. The diagnosis of MDD remains clinical, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria, as biomarkers have not yet been validated for diagnostic purposes or as predictors of treatment response. …”
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

“…The decision to continue randomising to arms after each stage will be made by the Trial Steering Committee who receive recommendations from the Independent Data Monitoring Committee. …”
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A Fortified Method to Screen and Detect Left Ventricular Hypertrophy in Asymptomatic Hypertensive Adults: A Korean Retrospective, Cross-Sectional Study by Hyo Eun Park, Sung-Bin Chon, Sang Hoon Na, Heesun Lee, Su-Yeon Choi

“…The diagnostic rule to detect LVH was made by summing up the rounded-off odds ratio of each independent variable and was validated using bootstrapping method. …”
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KIDS CLUB: CHILD-FRIENDLY HOTEL MARKETING STRATEGY by Dian Pramita Sugiarti, I Gede Anom Sastrawan

“…The activities offered by the hotel are painting, coloring, storytelling, drawing, watching movies, and outdoor activities, namely parks made with the concept of adventure. Hard Rock Hotel Bali is one of the hotels that provides a kids club with full activities divided by age and supporting facilities provided. …”
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The transcription factor dFOXO controls the expression of insulin pathway genes and lipids content under heat stress in <i>Drosophila melanogaster</i> by M. A. Eremina, P. N. Menshanov, O. D. Shishkina, N. E. Gruntenko

“…The deep homology of this pathway and its evolutionary conservative role in controlling the carbohydrate and lipid metabolism make it possible to use Drosophila melanogaster for studying its functioning. …”
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Role of the Bronchoalveolar Lavage in Noncritically Ill Patients during the SARS-CoV-2 Epidemic by Olivier Taton, Emmanuelle Papleux, Benjamin Bondue, Christiane Knoop, Sébastien Van Laethem, Alain Bauler, Delphine Martiny, Isabel Montesinos, Marie-Luce Delforge, Kahina Elmaouhab, Dimitri Leduc

“…Therapeutic management was changed in 33 patients because another infectious agent was identified in 23 patients or because an alternative diagnosis was made in 10 patients. In immunocompromised patients, the impact of BAL was even more marked (change in therapy for 13/17 patients). …”
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On the principles of building a model of a specialist – a graduate of a pedagogical university by K. S. Kаtаеv, S. G. Kаtаеv, I. V. Kаmenskaya

“…The block structure of the model makes it possible to analyse each block separately and together, selecting factors from different spaces, introducing new blocks or spaces of factors, oriented to the (possibly new) purpose of the study, without changing the others.Practical significance. …”
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Growth and molting of mud crab administered by different doses of vitomolt by Yushinta Fujaya

“… Vitomolt is a molting stimulant made from spinach (Amaranthus spp.) extracts.  The objective of this study was to optimize the dose of vitomolt injection on the growth and molting of mud crab (Scylla spp). …”
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Modified sutureless and glue-free method versus conventional sutures for conjunctival autograft fixation in primary pterygium surgery: a systematic review and meta-analysis by Faisal Aljahdali, Waleed Khayyat, Abdulelah T BinYamin, Sultan A Al-Qahtani, Mohammed D Alghamdi, Ali Saleh Alsudais, Husain A Alalgum, Halah Bin Helayel, Mohammed AlMutlak

“…Understanding the learning curve and surgeon familiarity with novel techniques is crucial for optimising patient care and surgical outcomes, while individualised decision-making is necessary considering the advantages and disadvantages of each approach. …”
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MUNet: a novel framework for accurate brain tumor segmentation combining UNet and mamba networks by Lijuan Yang, Lijuan Yang, Qiumei Dong, Da Lin, Chunfang Tian, Xinliang Lü

“…Brain tumors are one of the major health threats to humans, and their complex pathological features and anatomical structures make accurate segmentation and detection crucial. …”
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Prevalence, predictors and selected outcomes of early sexual initiation among adolescents in secondary schools in Lugbe, Abuja, Nigeria: a mixed methods study by Uchechi Grace Okonta

“…Descriptive and inferential statistical analysis was done including a binary logistic regression to determine the predictive factors and outcomes of early sexual initiation with statistical inference made at p value &lt;0.05.Results The prevalence of early sexual initiation was 11%; 80% of the respondents who had initiated sex did so before age 15, while 20% had first sex at ages between 15 and 19. …”
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Isolation, identification, and quantification of Prevotella intermedia and Prevotella nigrescens in subgingival plaque samples of periodontally healthy and chronic periodontitis pa... by Vijayalakshmi Sharadindu Kotrashetti, Kishore Gajanan Bhat, Vijay Mahadev Kumbar, Sachita Shrikant Naik

“…The molecular technique, used for isolating and identifying these species, requires specialized equipment, making them not feasible in a standard laboratory. …”
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The rise of congenital syphilis in Canada: threats and opportunities by Ashorkor Tetteh, Victoria Moore

“…A number of initiatives to improve syphilis care within the health care system and several community-based programs filling in some of the gaps in syphilis care and support are making important advances in addressing the epidemiological situation with syphilis.DiscussionMuch work is underway at various levels of government and local community to address the situation. …”
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How do consumers evaluate buffalo meat? by Ricardo Alexandre Silva Pessoa, Marilia Celeste Tavares Fernandes, María Luciana Menezes Wanderley Neves, Thales Freire Arival, Fabiana Carvalho Vasconcelos Pessoa

“…The most consumed meat cuts are those considered “day-to-day”, emphasizing the topside, knuckle, eye round, flat, minced meat, and sun-dried meat, making up 67.8% of the choices. Consumers reported choosing meat primarily considering cost accessibility, product quality, and sensory characteristics, high-lighting flavor and tenderness. …”
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The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs) by Patrizia Cancemi, Anna Aiello, Giulia Accardi, Rosalia Caldarella, Giuseppina Candore, Calogero Caruso, Marcello Ciaccio, Laura Cristaldi, Francesca Di Gaudio, Valentina Siino, Sonya Vasto

“…As far as we are concerned, it is difficult to make wide-ranging conclusions/assumptions based on these observations in view of the relatively small sample size of LLIs. …”
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Determination of Electrolytes in Critical Illness Patients at Different pH Ranges: Whom Shall We Believe, the Blood Gas Analysis or the Laboratory Autoanalyzer? by Christopher Hohmann, Roman Pfister, Kathrin Kuhr, Julia Merkle, Julian Hinzmann, Guido Michels

“…Data from our single-center study indicate that urgent and vital decisions based on potassium measurements can be made by trusting the value obtained on the ABG machine irrespective of pH values.…”
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Current issues of protection of land rights in local government bodies by Kovalenko T.

“…The results of the study can be used in the research field – for the further development of the problems of legislative regulation of the resolution of land disputes by local self-government bodies, as well as in the rule-making work – in the preparation of projects of normative legal acts aimed at improving the legislative regulation of the protection of land rights of land subjects legal relations in Ukraine.…”
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Resource potential of some species of the genus Miscanthus Anderss. under conditions of continental climate of West Siberian forest-steppe by O. V. Dorogina, O. Yu. Vasilyeva, N. S. Nuzhdina, L. V. Buglova, Yu. A. Gismatulina, E. V. Zhmud, G. A. Zueva, O. V. Kominа, Е. A. Tsybchenko

“…Therefore herbal perennial grasses with their rapid growth and prominent biomass yield increasingly make it a favorite choice as a valuable agricultural crop usable for cellulosic ethanol production. …”
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People’s knowledge, attitudes, and conflicts with carnivores in central hills, Sri Lanka by Ashan Thudugala, Hem Bahadur Katuwal, Nalindra Laxman, Vishwa Dushmantha, Ravindi Menikrama, Harsha Dissanayake, Chameera Dilshan, Ru-Chuan He, Rui-Chang Quan

“…Carnivores are found both within and outside protected areas, making them susceptible to human-carnivore conflicts. …”
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Impact of COVID-19 on metabolic parameters in patients with type 2 diabetes mellitus by Motahare Shabestari, Forouzan Salari, Reyhaneh Azizi, Akram Ghadiri-Anari, Nasim Namiranian

“…Abstract Background and aim The Coronavirus Disease 2019 (COVID-19) pandemic has disproportionately affected individuals with Type 2 Diabetes Mellitus (T2DM), making them more susceptible to viral infections. …”
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