Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids by Smriti Srivastava, Jun Luo, Daniel Whalen, Katherine N. Robertson, Amitabh Jha

“…The naphthalene-based amino-alcohols underwent double dehydrations and double intramolecular cyclization with oxo-acids leading to one-pot formation of a C-N bond, a C-O bond and an amide bond in tandem, to generate two additional rings completing the steroidal framework. …”
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Machine learning algorithms for predictive modeling of dyslipidemia-associated cardiovascular disease risk in pregnancy: a comparison of boosting, random forest, and decision tree... by Idris Zubairu Sadiq, Fatima Sadiq Abubakar, Muhammad Auwal Saliu, Babangida Sanusi katsayal, Aliyu Salihu, Aliyu Muhammad

“…Methods In this study, we utilized three different machine learning algorithms (boosting, random forest, and decision tree regression) to predict dyslipidemia-associated cardiovascular disease using atherogenic index and lipid profile parameters based on a cross-sectional study datasets of 112 pregnant women aged between 15 and 49 conducted at Aminu Kano Teaching Hospital. Results The results showed that random forest regression outperformed both boosting and decision tree regression, recording the lowest error criteria (MSE = 0.071 and RMSE = 0.266) for evaluating the model. …”
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Design, Synthesis, and In Vitro Kinetics Study of Atenolol Prodrugs for the Use in Aqueous Formulations by Rafik Karaman, Alaa Qtait, Khulod Khayyat Dajani, Saleh Abu Lafi

“…The calculations demonstrated that the amide bond cleavage is due to intramolecular nucleophilic catalysis by the adjacent carboxylic acid group and the rate-limiting step is determined based on the nature of the amine leaving group. …”
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Light-induced rearrangement from macrocyclic to bicyclic lactam: A case study of N-chlorinated laurolactam by Zubčić Gabrijel, Pavić Kristina, You Jiangyang, Vrček Valerije, Portada Tomislav, Bešić Erim, Šakić Davor

“…Laurolactam, a macrocyclic amide, exhibits significant potential for transformation into bioactive bicyclic structures with smaller, β-, γ-, δ-, and ε-lactam rings, further increasing rigidity and hydrolytic stability. …”
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Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins by Pavić Kristina, Poje Goran, Carvalho Lais Pessanha De, Held Jana, Rajić Zrinka

“…Testing of the antiproliferative activity of the new UT harmiquins, and previously prepared triazole-(TT) and amide-type (AT) CQ-based harmiquins, against a panel of human cell lines, revealed TT harmiquine 16 as the most promising compound, as it showed pronounced and selective activity against the tumor cell line HepG2 (IC50 = 5.48 ± 3.35 μmol L−1). …”
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Immobilization of Laccase in Alginate-Gelatin Mixed Gel and Decolorization of Synthetic Dyes by Mehdi Mogharabi, Nasser Nassiri-Koopaei, Maryam Bozorgi-Koushalshahi, Nastaran Nafissi-Varcheh, Ghodsieh Bagherzadeh, Mohammad Ali Faramarzi

“…Results showed that the maximum and minimum dye removal was related to amido black 10B and eosin, respectively.…”
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Optimization and Characterization of Silver Nanoparticle by Endophytic Fungi Penicillium sp. Isolated from Curcuma longa (Turmeric) and Application Studies against MDR E. coli and... by Dattu Singh, Vandana Rathod, Shivaraj Ninganagouda, Jyothi Hiremath, Ashish Kumar Singh, Jasmine Mathew

“…Further TEM revealed the formation of spherical, well-dispersed nanoparticles with size ranging between 25 and 30 nm and FTIR shows the bands at 1644 and 1538 cm−1 corresponding to the binding vibrations of amide I and II bands of proteins, respectively. Antibacterial activity against MDR E. coli and S. aureus showed good results showing maximum zone of inhibition of 17 mm and 16 mm, respectively, at 80 µL of AgNps.…”
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Theoretical Study of the Structural and Electronic Properties of NIPAM Polymer Dosimetry Gel by Swait S. Mohammed, Israa F. Al-sharuee, Akram Mohammed Ali, Adil Elrayah

“…Results: Based on the findings, it has been shown that NIPAM has a high-water solubility and is of great assistance in the process of introducing a powerful polar amide group into a hydrophobic polymer via the use of suspension or emulsion polymerization, and strong coupling effect (interaction of magnetic fields) between the hydrogen atoms and the deformation. …”
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Setting of residue definitions and toxicological reference values for ethiprole by European Food Safety Authority (EFSA), Sofia Batista Leite, Giulia Bellisai, Giovanni Bernasconi, Marco Binaglia, Luis Carrasco Cabrera, Irene Castellan, Anna Federica Castoldi, Arianna Chiusolo, Mathilde Colas, Federica Crivellente, Monica Del Aguila, Lucien Ferreira, Monica Fittipaldi Broussarad, Luna Greco, Frederique Istace, Samira Jarrah, Anna Lanzoni, Renata Leuschner, Jochem Louisse, Iris Mangas, Andrea Mioč, Stefanie Nave, Martina Panzarea, Juan Manuel Parra Morte, Hermine Reich, Simone Rizzuto, Silvia Ruocco, Alessia Pia Scarlato, Andrea Simonati, Marta Szot, Andrea Terron, Anne Theobald, Manuela Tiramani, Alessia Verani, Elena Zioga

“…A residue definition for risk assessment was derived as the ‘sum of ethiprole, ethiprole‐sulfone (RPA097973) and ethiprole‐amide (RPA112916), expressed as ethiprole’. This residue definition is applicable for foliar treatment in all primary crops, for both foliar and soil treatments in cereals crops, and is also valid for processed commodities.…”
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Case report: Local anesthesia with lidocaine infiltration for extended-release buprenorphine therapy by Pouya Azar, Pouya Azar, Jane J. Kim, Jane J. Kim, Ella Rohani, Dayyon Newman-Azar, Matin Narimani, Jessica Machado, Victor W. Li, Victor W. Li

“…Notwithstanding the advantages of BUP-XR, subjective pain and anxiety associated with injections can compromise patients’ willingness to receive treatment. Lidocaine is an amide-type agent and sodium channel blocker commonly used for local and regional anesthesia in various fields of medicine.Case presentationWe present two cases involving lidocaine infiltration to the induction phase of BUP-XR therapy in an outpatient setting. …”
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Antibiofilm effect of Nano chitosan and calcium hydroxide intracanal medications and their effects on the microhardness and chemical structure of radicular dentine by Maha Nasr, Ahmed Abdou, Dina M. Bassiouny, Reham Hassan

“…FTIR spectrum results revealed that the control group (no treatment) showed the highest significant Phosphate: amide ratio compared to both CSNPs and Ca(OH)2 at p = 0.006. …”
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Novel Derivatives of Phenylisoxazole-3/5-Carbaldehyde Semicarbazone: Synthesis, Characterization, and Computational Studies by Fernando Carrasco, Wilfredo Hernández, Oscar Chupayo, Rodolfo Pumachagua, Evgenia Spodine, Jackeline Mosquera, Olivio N. Castro, Jesus M. Rodilla, Celedonio M. Álvarez, Juan Z. Dávalos

“…The MEP descriptors indicate that the oxygen atom of the carbonyl group C=O is susceptible to electrophilic attack, while the hydrogen atoms of the amide and hydrazone fragments are sensitive to nucleophilic attack. …”
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APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage by Xiaojing Wang, Keisuke Ishimatsu, Junjie Li, Xiaodong Wen, Weijun Ou, Arnida Anwar, Jaideep Chaudhary, Masaya Takahashi, A Dean Sherry, Ian R Corbin

“…Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated in models of diethylnitrosamine (DEN) induced HCC, N1S1 syngeneic orthotopic xenograft and human HepG2 ectopic xenograft.Results: All models of HCC showed a higher APTw signal over the surrounding normal tissues. …”
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Azurin a potent anticancer and antimicrobial agent isolated from a novel Pseudomonas aeruginosa strain by Nourhan A. Zaghloul, Mona K. Gouda, Yasser Elbahloul, Nancy M. El Halfawy

“…Moreover, FTIR spectroscopy revealed characteristic amide I and II absorption peaks (1500–1700 cm− 1), revealing the possible secondary structure of azurin. …”
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Documenting and Reporting Implementation Strategies of Vaccination Efforts (DRIVE) framework for fostering systems learning to enhance cross-context replication in immunization pro... by Abdu A. Adamu, Amos Petu, Balcha G. Masresha, Blaise Bathondoli, Rabiu Ibrahim Jalo, Duduzile Ndwandwe, Charles S. Wiysonge

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Сhanges in subcellular distribution of lysosomal cysteine proteinases activity in parenchymatous organs of rats under the action of nitric oxide synthesis modulators by M. A. Fomina, A. A. Terent'ev

“…The effects of non-selective inhibitor and substrate of nitric oxide synthesis on the total activity of cathepsins B, L and H in parenchymatous organs and its subcellular distribution are tissue-specific and multidirectional in some cases and are accompanied by signs of changes in the ratio of pro-enzyme and enzymatically active forms mainly due to an increase of pro-enzyme forms.…”
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Green Synthesis of Silver Nanoparticles Incorporated Aromatherapies Utilized for Their Antioxidant and Antimicrobial Activities against Some Clinical Bacterial Isolates by Ahmed A. H. Abdellatif, Sultan S. Alhathloul, Abdullah S. M. Aljohani, Hamzah Maswadeh, Emad M. Abdallah, Khalid Hamid Musa, Mohamed A. El Hamd

“…The FTIR shows the involvement of amide (-CO-NH2), carbonyl (-CO), and hydroxyl (-OH), which resulted in the reduction of AgNPs. …”
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Antifungal Activity of New Eugenol-Benzoxazole Hybrids against Candida spp. by Larissa Incerti Santos de Carvalho, Dalila Junqueira Alvarenga, Letícia Cruz Ferreira do Carmo, Lucas Gomes de Oliveira, Naiara Chaves Silva, Amanda Latércia Tranches Dias, Luiz Felipe Leomil Coelho, Thiago Belarmino de Souza, Danielle Ferreira Dias, Diogo Teixeira Carvalho

“…The products were obtained in good yields by a four-step synthetic sequence involving aromatic nitration, nitroreduction, amide formation, and cycle condensation. They were evaluated against species of Candida spp. in microdilution assays, and four products (5a, 5b′, 5c, and 5d′) were about five times more active than eugenol against C. albicans and C. glabrata. …”
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RETRACTED: Pyrene-Phosphonate Conjugate: Aggregation-Induced Enhanced Emission, and Selective Fe³⁺ Ions Sensing Properties by Sachin D. Padghan, Rajesh S. Bhosale, Sidhanath V. Bhosale, Frank Antolasic, Mohammad Al Kobaisi, Sheshanath V. Bhosale

“…A new pyrene-phosphonate colorimetric receptor <b>1</b> has been designed and synthesized in a one-step process via amide bond formation between pyrene butyric acid chloride and phosphonate-appended aniline. …”
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Isotherms and Kinetic Studies of Copper Removal from Textile Wastewater and Aqueous Solution Using Powdered Banana Peel Waste as an Adsorbent in Batch Adsorption Systems by Momina Seleman, Takele Sime, Abate Ayele, Assefa Sergawie, Thabo Nkambule, Jemal Fito

“…The main objective of this study is to evaluate the effective powdered banana peel for the removal of copper (II) from aqueous solutions and real wastewater. …”
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