Validation of an UHPLC-MS/MS Method for Screening of Antimicrobial Residues in Eggs and Their Application to Analyses of Eggs from Laying Hens Subjected to Pharmacological Treatmen... by Letícia Gomes Magnago Caldeira, Flávio Alves Santos, Andréa Melo Garcia de Oliveira, Josefa Abucater Lima, Leonardo Francisco de Souza, Guilherme Resende da Silva, Débora Cristina Sampaio de Assis, Silvana de Vasconcelos Cançado

“…A multiresidue method by UHPLC/MS-MS was optimized and validated for the screening and semiquantitative detection of antimicrobials residues from tetracyclines, aminoglycosides, quinolones, lincosamides, β-lactams, sulfonamides, and macrolides families in eggs. A qualitative approach was used to ensure adequate sensitivity to detect residues at the level of interest, defined as maximum residue limit (MRL), or less. …”
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Extensive Mycobacterium abscessus Pneumonia in an Immunocompetent Infant with No Underlying Lung Pathology by Morouge M. Alramadhan, James R. Murphy, Michael L. Chang

“…A complete multidisciplinary evaluation for underlying lung disease and primary and acquired immunodeficiency should be undertaken in pediatric patients with M. abscessus pneumonia. Confirming macrolide susceptibility through erm(41) gene evaluation is clinically important for isolates with complicated susceptibility pattern.…”
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Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease by Helen C. Steel, Riana Cockeran, Ronald Anderson, Charles Feldman

“…This is focused on macrolides, corticosteroids, and statins with respect to their modes of anti-inflammatory action, current status, and limitations.…”
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IDENTIFICATION AND ANTIMICROBIAL RESISTANCE OF <i>SALMONELLA ISOLATES by G. S. Skitovich, N. B. Shadrova, O. V. Pruntova, K. V. Serova, S. Ye. Shmaihel

“…The performed tests for antimicrobial resistance demonstrated that all isolates were susceptible to the following antibiotics: carbpenemes (meropenem, imipenem), β-lactams (amoxicillin /clavulanate), aminoglycoside (amikacin, gentamycine), macrolides (azithromycin). Most of the isolates demonstrated susceptibility to β-lactam antibiotics (ceftriaxone, cefotaxime), fluoroquinolones (ciprofloxacin) and aminoglycosides (kanamycin). …”
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New Role of Quinolones in Respiratory Tract Infections by Ronald F Grossman

“…A new parenteral quinolone with pneumococcal activity may replace the standard macrolide/cephalosporin combination that is commonly prescribed. …”
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Diffuse panbronchiolitis as a rare complication of thymectomy and radiation therapy in a patient with thymoma: a case report by Ye Lu, Qi Qi, Dan Qu, Yu Chen

“…Early treatment with macrolides can improve patient prognosis.…”
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Antibiotic Residues in Animal Products from Some African Countries and Their Possible Impact on Human Health by Oluwaseun Mary Oladeji, Liziwe Lizbeth Mugivhisa, Joshua Oluwole Olowoyo

“…The findings showed that the most prevalent groups of antibiotic residues were aminoglycoside, macrolides, β-lactams, fluoroquinolones, tetracyclines sulfonamides, and phenicols. …”
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Carriage Methicillin-Resistant Staphylococcus aureus in Poultry and Cattle in Northern Algeria by Saliha Bounar-Kechih, Mossadak Taha Hamdi, Hebib Aggad, Nacima Meguenni, Zafer Cantekin

“…While MRSA strains isolated from poultry showed cross-resistance to aminoglycosides, fluoroquinolones, macrolides, sulphonamides, and cyclins, those isolated from bovine also revealed similar multiresistance except for sulphonamide. …”
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Omadacycline for the Treatment of Severe Legionella Pneumonia Complicated with Multiple Organ Failure: A Case Report by Xu L, Xiong Y, Fang C

“…Limin Xu,1 Ying Xiong,2 Changquan Fang2 1Department of Geriatrics, Huizhou First Hospital, Huizhou, Guangdong Province, Peoples’ Republic of China; 2Department of Pulmonary and Critical Care Medicine, Huizhou Central People’s Hospital, Huizhou, Guangdong Province, Peoples’ Republic of ChinaCorrespondence: Changquan Fang, Department of Pulmonary and Critical Care Medicine, Huizhou Central People’s Hospital, Huicheng District, Huizhou City, Guangdong Province, 516000, Peoples’ Republic of China, Tel +86 137 5155 1071, Email 314499072@qq.comBackground: Fluoroquinolones and macrolides are the preferred antibiotics for treating Legionnaires’ disease. …”
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Evaluation of Possible Genotoxic Activity of Dirithromycin in Cultured Human Lymphocytes by Ahmet Kayraldız, Lale Dönbak, Ayşe Yavuz Kocaman, Esra Köker, Şule Gökçe

“…Dirithromycin antibiotic is a 14-membered lactone ring macrolide and is widely used in medicine to treat many different types of bacterial infections. …”
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Antibiotic resistance gene occurrence in poultry farms in northeast Brazil by Henrique Francisco de Almeida, Paulo Ricardo Conceição Marques Trindade, César Roberto Viana Teixeira, Claudson Oliveira Brito, Silvio Santana Dolabella, Sona Jain, Maíra Pompeu Martins, Ana Andréa Barbosa

“…ARGs were confirmed in all samples, and the highest resistance positivity was obtained for tetracyclines (tetA, tetM, and tetG), quinolones (gyrA and qnrS), beta-lactams (blaTEM), macrolides (ermB) and sulfonamides (sul-1). Sequencing and comparison with the GenBank database confirmed the identity of the ARGs. …”
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Bacterial Multiresistance and Microbial Diversity of Milk Received by a University Hospital Milk Bank by Dayane da Silva Zanini, Benedito Donizete Menozzi, Wanderson Sirley Reis Teixeira, Felipe Fornazari, Gismelli Cristiane Angeluci, Raquel Cuba Gaspar, Lucas Franco Miranda Ribeiro, Carlos Eduardo Fidelis, Marcos Veiga dos Santos, Juliano Gonçalves Pereira, Helio Langoni

“…Resistance to antimicrobials varied among species, with a higher percentage of isolates resistant to penicillins and macrolides. Multidrug resistance was identified in 12.6% of 143 isolates. …”
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Pulsed Electric Field Induces Significant Changes in the Metabolome of <i>Fusarium</i> Species and Decreases Their Viability and Toxigenicity by Adam Behner, Jana Palicova, Anna-Hirt Tobolkova, Nela Prusova, Milena Stranska

“…The metabolomes of the treated and untreated fungi showed statistically significant differences, and PEF-associated biomarkers from the classes oxidized fatty acid derivatives, cyclic hexapeptides, macrolides, pyranocoumarins, carbazoles, and guanidines were identified.…”
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Characteristics of lower respiratory microbiota in children’s refractory Mycoplasma pneumoniae pneumonia pre- and post-COVID-19 era by Zhimin Xi, Jinglong Chen, Libo Wang, Aizhen Lu

“…Mycoplasmoides pneumoniae was the top species of the LRT microbiota in both groups. The rate of macrolide resistance MP in Y2023 was significantly higher than that in Y2019 (P&lt;0.05), and the mutant site was all 23S rRNA A2063G. …”
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A Reliable Method for Identification of Antibiotics by Terahertz Spectroscopy and SVM by Jin Guo, Hu Deng, Quancheng Liu, Linyu Chen, Zhonggang Xiong, Liping Shang

“…THz time-domain spectroscopy (THz-TDS) was performed for sixteen types of antibiotics, including β-lactam, cephalosporins, macrolides, and tetracyclines. The absorption spectra within the frequency range of 0.2–1.5 THz were calculated. …”
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Improvement of Helicobacter pylori eradication efficacy at stomach and duodenum peptic ulcers by Natalya O. Schanova, Lyudmila V. Prokhorova

“…Growth of H. pylori antibiotic resistance requires accumulation of the Russian data on efficacy of sequential therapy to increase eradication rate and prevent growth of macrolide resistance. Sequential therapy was proposed as a way to overcome resistance to clarithromycin. …”
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Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…Extreme Streptomyces have been an excellent source of a new class of compounds which include alkaloids, angucycline, macrolide, and peptides. This review covers novel drug leads with antibacterial and cytotoxic activities isolated from deep-sea, desert, cryo, and volcanic environment Streptomyces from 2009 to 2019. …”
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Genomic insights into a clinical Salmonella Typhimurium isolate carrying plasmid-mediated blaNDM-5 by Fan Huang, Genglin Guo, Lu Feng, Tongbo Cai, Xu Huang

“…Furthermore, blaNDM-carrying isolates are mostly resistant to beta-lactams, aminoglycosides, sulphonamide, macrolides, and trimethoprim. Conclusions: These findings provided thorough and intuitive insights into the intercontinental spread of blaNDM-carrying Salmonella. …”
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The effect of the nisin-based pharmaceutical formulation used in the treatment plan for cows with subclinical mastitis on the milk microbiota by M. N. Isakova, Ya. Yu. Lysova

“…The study showed that a significant number of Staphylococcus aureus isolates (53.1%) were resistant to I generation cephalosporins; 52.6% of the isolated Streptococcus dysgalactiae strains showed resistance to tetracyclines; 33.3% of Staphylococcus haemolyticus isolates were resistant to macrolides. 42.1; 35.3 and 62.5% of Enterococcus faecium, Aerococcus viridans and coliform bacteria isolates, respectively, were resistant to penicillins. 38.5% of Staphylococcus epidermidis isolates were found to be resistant to tetracyclines. …”
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Assessment of microbial diversity and antimicrobial resistance in raw camel milk: Genomic and phenotypic analysis of Kharai and Kutchi breeds of Gujarat, India by Hetvi J. Adhyaru, Devangi B. Mangroliya, Jayesh H. Kabariya, Vimal M. Ramani

“…In the Kharai breed 58 ARGs were detected, majority of them conferring resistance to fluoroquinolones, tetracycline, macrolides, and colistin. In contrast, 13 ARGs were detected in the Kutchi breed, with a focus on resistance to fluoroquinolones and spectinomycin. …”
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