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  1. 161

    Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction by Elizabeth J. Wright, Nigel W. Hodson, Michael J. Sherratt, Moustapha Kassem, Andrew L. Lewis, Christine Wallrapp, Nadim Malik, Cathy M. Holt

    Published 2016-01-01
    “…The effect on cardiac remodeling when encapsulated in alginate beads (CellBeads-MSC and CellBeads-MSC + GLP-1) was also evaluated in a pig MI model, whereby pigs were treated with Empty Beads, CellBeads-MSC, or CellBeads-MSC + GLP-1 and sacrificed at one or four weeks following MI. …”
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  2. 162

    Theoretical and Practical Issues That Are Relevant When Scaling Up hMSC Microcarrier Production Processes by Valentin Jossen, Cedric Schirmer, Dolman Mostafa Sindi, Regine Eibl, Matthias Kraume, Ralf Pörtner, Dieter Eibl

    Published 2016-01-01
    “…Recent publications focusing on microcarrier-based stirred bioreactors have demonstrated the successful use of Computational Fluid Dynamics (CFD) and suspension criteria (NS1u, NS1) for rapidly scaling up hMSC expansions from mL- to pilot scale. Nevertheless, one obstacle may be the formation of large microcarrier-cell-aggregates, which may result in mass transfer limitations and inhomogeneous distributions of stem cells in the culture broth. …”
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  3. 163

    MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production by Xinrui Yang, Jing Liu, Yaru Yin, Luxun Yang, Mingquan Gao, Zifei Wu, Binghui Lu, Shenglin Luo, Weidong Wang, Rong Li

    Published 2025-01-01
    “…In this study, we investigate the therapeutic potential of human umbilical cord-derived mesenchymal stem cell exosomes (MSC-EXs) in mice exposed to DU. Our results showed that MSC-EXs could ameliorate renal damage and enhance kidney and bone marrow morphology but also effectively promote uranium excretion while reducing internal retention. …”
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  7. 167

    SSL-MBC: Self-Supervised Learning With Multibranch Consistency for Few-Shot PolSAR Image Classification by Wenmei Li, Hao Xia, Bin Xi, Yu Wang, Jing Lu, Yuhong He

    Published 2025-01-01
    “…Based on the abovementioned issues, we propose an SSL model with multibranch consistency (SSL-MBC) for few-shot PolSAR image classification. Specifically, the data augmentation technique used in the pretext task involves a combination of various spatial transformations and channel transformations achieved through scattering feature extraction. …”
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  8. 168

    hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts by Yifei Wang, Yaqin Zhang, Bing Lu, Jianbo Xi, Dickson Kofi Wiredu Ocansey, Fei Mao, Donglin Hao, Yongmin Yan

    Published 2023-01-01
    “…We established a DSS-induced mouse IBD-related intestinal fibrosis model and observed the effect of hucMSC-Ex on the mouse model. We also used the TGF-induced human intestinal fibroblast CCD-18Co to observe the role of hucMSC-Ex in the proliferation, migration, and activation of intestinal fibroblasts. …”
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  9. 169

    hMSC成骨分化相关lncRNA的筛选和初步鉴定 by 罗嘉全

    Published 2014-01-01
    “…【目的】 筛选和初步鉴定人骨髓间充质干细胞(hMSC)成骨分化相关的长链非编码RNA (lncRNA)? 【方法】 利用Refseq, UCSC knowngenes, Ensembl ,H-invDB 7.0, RNAdb 2.0, NRED生物软件分析成骨基因相关的lncRNA,综合获得可能的成骨相关lncRNA;3例骨髓标本来源于行腰椎手术患者,密度梯度法分离扩增hMSC后,分成骨诱导组和对照组,地塞米松?…”
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  10. 170

    Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2 by Zhongsheng Zhou, Shuhui Wu, Yang Li, Pu Shao, Jinlan Jiang

    Published 2025-01-01
    “…In the rat arthritis model, the combination of MSC-exo and Rh2 showed synergistic therapeutic effects. …”
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  14. 174

    Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

    Published 2025-02-01
    “…The neuroprotective effects of hMSC-L and hMSC-M were assessed with TTC staining, behavioral tests and pathological staining. …”
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  15. 175

    Proteomic profiling of iPSC and tissue-derived MSC secretomes reveal a global signature of inflammatory licensing by Margeaux Hodgson-Garms, Matthew J. Moore, Mikaël M. Martino, Kilian Kelly, Jessica E. Frith

    Published 2025-02-01
    “…Understanding these differences is essential to define the mechanisms of MSC-based tissue repair and optimise cell therapies. …”
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  16. 176

    The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

    Published 2025-02-01
    “…This study focused on exosomes derived from stem cells of human exfoliated deciduous teeth (SHED-MSC-EXOs) and their role in managing the balance of immunoregulatory macromolecules that play a role in the underlying immunoregulatory mechanisms in THP-1-derived M0/M1 macrophage cells.MethodsFlow cytometry confirmed the expression of CD14, CD68, CD80, and CD86 markers in these macrophages. …”
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    hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination by Shanshan Xiao, Ying Lv, Xuejing Hou, Shuqiang Qu

    Published 2024-12-01
    “…This study explores how hUC-MSC-EVs protect neonatal rats from HIBD. hUC-MSC-EVs were isolated, characterized, and administered to neonatal rats subjected to HIBD. …”
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