Intrathecal magnesium sulphate as an adjuvant to bupivacaine for infraumbilical surgeries: An updated systematic review and meta-analysis by Mohamed Mohamed Belal, Osama Mohammad Alazki, Mohamed Nabih Bashir, Lana Yousef Sbitan, Douaa Albelal, Farah Albakkar, Abdelrahmanh H. Hafez, Ayman Issa Nabhan

“…Results: Thirty-two studies (2379 patients) were included. Adding intrathecal MgSO4 to bupivacaine significantly prolonged the time for regression of two segments from the maximum height (MD: 27.18 min; 95% CI: 12.56, 41.79; P = 0.0003), delayed the onset of sensory block to T10 (MD: 1.93 min; 95% CI: 1.10, 2.77; P < 0.0001), prolonged the duration of motor block (Bromage score = 0) (MD: 15.13 min; 95% CI: 4.59, 25.66; P = 0.005) and extended time for first rescue analgesia (MD: 43.80 min; 95% CI: 26.47, 61.14; P < 0.00001). …”
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A 5-HT Antagonist (UP 26-91) versus Codeine and Placebo in a Human Experimental Pain Study by Lars Arendt-Nielsen, Poul Pedersen, Lars Poulsen, Ole Kæseler Andersen, Peter Bjerring, Isabelle Coste, Jorge Insuasty, Søren Sindrup, Asbjørn Mohr Drewes

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Treatment Challenges in a Tourette Syndrome Patient with Self-Injurious Behaviour: Case Report and Literature Review by G. Asadauskaitė, G. Jasionytė, M. Karnickas

“…Tourette syndrome is known as a combined vocal and multiple motor tic disorder. It is a chronic complex neuropsychiatric disorder characterised by the onset of symptoms in early childhood and the presence of multiple motor tics and one or more vocal tics. …”
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Anti-Parkinson Activity of Petroleum Ether Extract of Ficus religiosa (L.) Leaves by Jitendra O. Bhangale, Sanjeev R. Acharya

“…Daily administration of PEFRE (400 mg/kg) significantly improved motor performance and also significantly attenuated oxidative damage. …”
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Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinica... by Simin Azemati, Amir Zarghami, Reza Jouybar, Vida Naderi-boldaji

“…In this double-blind randomized clinical trial study, ninety pregnant women were divided into groups to receive 10 mg bupivacaine (group B), 10 mg bupivacaine with 5 μg dexmedetomidine (group BD), or 10 mg bupivacaine with 10 mg meperidine (group BM) intrathecal. …”
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Does the Use of Nitroglycerin Patch Improve Local Anaesthetic Effects in Bier’s Block? A Double-Blind Placebo Controlled Study by Ahmed Said Elgebaly

“…The patients were divided into two equal groups as follows: Group C received only lidocaine (1.5 mg/kg, 0.25%) and Group N received lidocaine (1.5 mg/kg, 0.25%) + 5 mg transcutaneous nitroglycerin patch. …”
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Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…In PD patients who crossed the 800 mg threshold between two consecutive clinic visits, a significant improvement in depressive symptoms and quality-of-life measures was demonstrated, and in these patients there was no worsening of motor fluctuations or dyskinesia.Conclusions The data suggest that PD patients have the potential for enhanced clinical benefits when eclipsing the 800 mg carbidopa/levodopa threshold. …”
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Oil-water emulsion separation on surface-modified capillary ultrafiltration membranes by A. S. Ilyinykh, E. V. Migalatiy, A. V. Korneev

“…Surface modification had a positive effect on the retention efficiency of petroleum products. In the case of motor oil emulsion separation, the efficiency reached 99 %, and the content of oil products in all filtrate samples was below 0.4 mg/l. …”
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EFFECT OF Zanthoxylum acanthopodium DC EXTRACT ON THE INCREASE OF BRAIN CELLS IN THE SUBSTANTIA NIGRA OF WISTAR RATS THAT ARE ROTENONE-INDUCED by Shalli hafizha, Binarwan Halim, Linda Chiuman

“…The administration of extracts at doses of 150 mg/kgBB, 300 mg/kgBB, and 450 mg/kgBB can increase the regeneration of brain cells that experience necrosis. …”
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Wearable devices may aid the recognition of fluctuation-related pain in Parkinson's disease-An exploratory, cross-sectional analysis of two prospective observational studies. by Katarina Rukavina, Juliet Staunton, Pavlos Zinzalias, Magdalena Krbot Skoric, Kit Wu, Kirsty Bannister, Alexandra Rizos, K Ray Chaudhuri

“…The National Institute for Health and Care Excellence (NICE) recommends The Parkinson KinetiGraphTM (the PKGTM) for remote monitoring of motor symptoms. We investigated potential links between the PKGTM-obtained parameters and clinical rating scores for FRP in PwP in an exploratory, cross-sectional analysis of two prospective studies: "The Non-motor International Longitudinal, Real-Life Study in PD-NILS" and "An observational-based registry of baseline PKG™ in PD-PKGReg". 63 PwP (41.3% female; age: 64.24±9.88 years; disease duration, DD: 6.83±5.63 years; Hoehn and Yahr Stage, H&Y: 2 (1-4); Levodopa Equivalent Daily Dose 535 (0-3230) mg) were included. …”
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Effects of Intrathecal Bupivacaine with Adjuvants Midazolam versus Magnesium Sulphate in Tibia Fibula Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Aanal Sha, Dushyant Chavda, Dinesh K Chauhan

“…Aim: To observe the efficacy of intrathecal 2.5 mg midazolam and 50 mg magnesium sulphate as adjuvants to 0.5% hyperbaric bupivacaine in tibia-fibula surgeries and haemodynamic stability in both groups. …”
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Effect of Zbtb33 gene knockout and bacterial lipopolysaccharide on home cage behavior in mice by N. V. Khotskin, I. E. Sorokin, E. A. Kulikova, A. V.  Kulikov

“…LPS at both doses suppressed motor activity, prolonged sleep duration and caused anorexia in mice of both genotypes. …”
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Immobilisation and Epidural Anaesthesia in a Eurasian Lynx (Lynx lynx) Undergoing Pelvic Limb Orthopaedic Surgery by Sonia Campos, Pierre Picavet, Olivier Bertrand, Charlotte Sandersen, Alexandru Tutunaru

“…The animal was remotely darted using a combination of ketamine (5 mg/kg) and xylazine (5 mg/kg) intramuscularly. Once immobilised, the lynx was transported to the veterinary hospital in a restraining cage. …”
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Collective Expert Perspectives on the Use of Safinamide as Adjunctive Therapy for Parkinson’s Disease: Online-Based Delphi Survey by Atsushi Takeda, Yoshio Tsuboi, Masahiro Nomoto, Hideki Mochizuki, Nobutaka Hattori

“…The use of high-dose safinamide (100 mg/day) was recommended when the improvement in PD symptoms is insufficient and increasing the doses of other anti-PD medications is difficult (97.8%) or when the abovementioned non-motor symptoms adversely affect daily life (93.5%). …”
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7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents by Shuke Nie, Kai Ma, Mingkuan Sun, Matthew Lee, Yang Tan, Guiqin Chen, Zhentao Zhang, Zhaohui Zhang, Xuebing Cao

“…The major purpose of this study was to investigate the neuroprotective effects of 7,8-DHF on the rotenone-induced motor deficit of Parkinson’s disease. Nine-month-old rats were treated with rotenone (2 mg/kg/day, i.h.) for 5 weeks to establish the animal model of Parkinson’s disease (PD), and 7,8-DHF (5 mg/kg, i.p.) was administrated daily throughout the whole period of rotenone injection. …”
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Antioxidant radical scavenging capacity and total carotenoid content of narrow-clawed crayfish (Pontastacus leptodactylus, Eschscholtz, 1823) in Atikhisar Reservoir (Çanakkale, Tür... by Acarlı Sefa, Kızılkaya Bayram, Vural Pervin, Berber Selçuk, Kale Semih, Acarlı Deniz

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Evaluation of preemptive pregabalin efficacy on block characteristics and postoperative analgesia in patients undergoing infra-umbilical surgeries under spinal anesthesia: A prospe... by Indira Kumari, Swati Dhania, Surendra Kumar Sethi, Santosh Choudhary, Ipra Jain, Vidhu Yadav

“…Duration of sensory block was the primary objective while onset of sensory and motor block, duration of motor block and analgesia, rescue analgesic consumption, and side effects were secondary objectives. …”
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Features of the use of physical exercises at the long-term stage of rehabilitation after intra-articular fractures by Sviatoslava Pashkevych, Tetiana Shutieieva, Оlha Beziazychna

“…The main demand after surgical treatment of the injury is to restore motor function and return to an active lifestyle. …”
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Influence of Positioning on Plain Levobupivacaine Spinal Anesthesia in Cesarean Section by Fabio Gori, Francesco Corradetti, Vittorio Cerotto, Vito Aldo Peduto

“…Spinal anesthesia with 12.5 mg levobupivacaine was performed in the sitting position in all women. …”
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Evaluation of the Neuroprotective Effect of Lawsonia inermis Flower Extract in Alzheimer’s Disease-induced Zebrafish Model by Kavitha Ramasamy, K. Priya Gayathri, Binoy Varghese Cheriyan, I. Glory Josephine, V. D. Deepti

“…In Phase II, the effective dose (8 μg/day/0.5 mg fish) of L. inermis flower extract has shown a significant reduction in anxiety, degeneration, and motor dysfunction with a significant increase in memory and learning. …”
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