-
2561
Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes
Published 2025-01-01“…Methods We used the macaque Genotype and Phenotype (mGAP) resource consisting of 2,054 macaque genomes to examine patterns of evolutionary constraint in known human neurodevelopmental genes. …”
Get full text
Article -
2562
Running trends in Switzerland from 1999 to 2019: An exploratory observational study.
Published 2025-01-01“…With focus on participation numbers, performance or sex difference, many single study results were obtained. The running trends in a whole country covering a longer period of time and several race distances are missing so far.…”
Get full text
Article -
2563
Association Between Diabetic Control And Anti-Diabetic Medication Adherence Using 8-Point Morisky Medication Adherence Scale In Local Population Of Khyber Pakhtunkhwa
Published 2023-06-01“… Abstract: Background: Drug adherence to medications in diabetes is very necessary for strict glycemic control. Many factors in diabetics are associated with low adherence to drugs resulting in complications. …”
Get full text
Article -
2564
Long-term risk factors for developing Barrett’s oesophagus in patients with gastro-oesophageal reflux disease: a longitudinal cohort study
Published 2024-06-01“…Most were Caucasian (n=1188, 99%), had no formal educational qualifications (n=714; 59.6%) and lived with overweight (mean body mass index >25 kg/m2). Many lived in areas of least socioeconomic resource (n=568; 47.4%). 139 (11.6%) had BO at baseline. …”
Get full text
Article -
2565
Reduction reactions dominate the interactions between Mg alloys and cells: Understanding the mechanisms
Published 2025-03-01“…Depending on the corrosion rate, Mg modulates HIF1α and many signaling pathways like PI3K/AKT/mTOR, mitophagy, cell cycle, and oxidative phosphorylation. …”
Get full text
Article -
2566
Genes related to neural tube defects and glioblastoma
Published 2025-01-01“…Abstract There are many similarities between early embryonic development and tumorigenesis. …”
Get full text
Article -
2567
Fiber-tip photonic crystal for real-time referenced biosensing in serum
Published 2025-03-01“…Fiber optic sensors have become increasingly well-established due to the many advantages they provide such as immunity to electromagnetic interference, multiplexing capabilities, and remote sensing. …”
Get full text
Article -
2568
Predatory bacteria can intensify lung-injury in a multidrug-resistant Acinetobacter baumannii pneumonia model in rat
Published 2025-01-01“…Also, the colistin MIC value for B. bacteriovorus HD100 (8 μg/mL) was determined for the first time to our knowledge. …”
Get full text
Article -
2569
Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC
Published 2025-03-01“…Methods: Explored CDC6 mRNA and protein expression in normal human tissues and tumors using TCGA, GTEx, and HPA. …”
Get full text
Article -
2570
Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars
Published 2018-03-01“…Garlic (Allium sativum L.) has a reputation as a therapeutic agent for many different diseases such as microbial infections, hypertension, hypercholesterolaemia, diabetes, atherosclerosis and cancer. …”
Get full text
Article -
2571
Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study
Published 2020-01-01“…Radix Polygoni Multiflori (RPM) has been widely used to treat various diseases in Asian countries for many centuries. Although, stilbenes and anthraquinones, two major components of RPM, show various bioactive effects, it has been speculated that the idiosyncratic hepatotoxicity induced by RPM may be related to these constituents. …”
Get full text
Article -
2572
Alginate-based encapsulation of porcine placenta extract: Preparation, enteric sustained release, biological activities, and stability
Published 2025-06-01“…Generally, the F2 microbeads contained 57.5 µg/mL of pPE with 99.72 % entrapment efficiency. The average size measured by Mastersizer was 14.65 ± 0.08 µm. …”
Get full text
Article -
2573
Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38−/− Mice
Published 2019-01-01“…CD38 is one of the well-known regulators of innate immunity, whose dysregulation contributes to sepsis. Many studies have proven that an attenuated Gram-positive bacterium induces sepsis in a CD38-blocking model. …”
Get full text
Article -
2574
Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae)
Published 2012-01-01“…Leishmania (L.) chagasi is the etiological agent of visceral leishmaniasis, an important endemic zoonosis in the American continent, as well as in many other countries in Asia, Africa, and Mediterranean Europe. …”
Get full text
Article -
2575
Excitation of ULF, ELF, and VLF Resonator and Waveguide Oscillations in the Earth–Atmosphere–Ionosphere System by Lightning Current Sources Connected with Hunga Tonga Volcano Erupt...
Published 2025-01-01“…The spectrum is monotonous in the VLF range but has many significant details at the lower frequencies (ULF, ELF). …”
Get full text
Article -
2576
A Performance Evaluation and Inter-laboratory Comparison of Community Face Coverings Media in the Context of COVID-19 Pandemic
Published 2021-02-01“…This specification imposes a minimal air permeability of 96 L m−2 s−1 for a 100 Pa pressure drop and a minimal filtration efficiency of 70% for 3 µm diameter particles. …”
Get full text
Article -
2577
Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications
Published 2021-01-01“…The effect of polyrhodanine- (PR-) based materials on human cells can be considered a controversial matter, while many contradictions exist. In this study, we focused on the synthesis of polyrhodanine/Fe3O4 modified by graphene oxide and the effect of kombucha (Ko) supernatant on results. …”
Get full text
Article -
2578
Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells
Published 2025-01-01“…The renal tissue SGLT2 mRNA amounts and the number of renal proximal tubules with overexpressed SGLT2 in the lumen were more in the Fn-LPS-administered-diabetic mice than in diabetic mice. …”
Get full text
Article -
2579
Recalcitrant Female Pattern Hair Loss Like Alopecia Unveils Unexpected Rare Entity
Published 2025-01-01“…While MUHH mainly affects hair, it may also be linked to other conditions such as skin tumors (trichoepithelioma), limb abnormalities, eye issues, wide-spaced teeth, and syndromes like Ehlers-Danlos or atopy.Because MUHH is so rare, diagnosing it can be difficult, and many healthcare providers may not immediately recognize it. …”
Get full text
Article -
2580
Exploring individual differences in online and face-to-face help-seeking intentions in case of impending mental health problems: The role of adult attachment, perceived social supp...
Published 2016-11-01“…Background: Even though common mental health problems such as depression are a global burden calling for efficient prevention strategies, still many distressed individuals face hurdles to access public mental healthcare. …”
Get full text
Article