Glycopatterns of Urinary Protein as New Potential Diagnosis Indicators for Diabetic Nephropathy by Hanyu Zhu, Moyan Liu, Hanjie Yu, Xiawei Liu, Yaogang Zhong, Jian Shu, Xinle Fu, Guangyan Cai, Xiangmei Chen, Wenjia Geng, Xiaoli Yang, Minghui Wu, Zheng Li, Dong Zhang

“…Presently, we interrogated glycopatterns in urine specimens using a lectin microarray. The results showed that expression levels of Siaα2-6Gal/GalNAc recognized by SNA exhibited significantly increased tendency with the development of diabetic nephropathy; moreover, SNA blotting indicated glycoproteins (90 kDa, 70 kDa, and 40 kDa) in urine may contribute to this alteration. …”
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Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with Asthma by Jones AW, McDonald VM, McLoughlin RF, Vella TM, Flynn AW, Blakey JD, Wolfenden L, Hew M, Upham JW, Thomas D, Bardin P, Holland AE

“…Arwel W Jones,1 Vanessa M McDonald,2– 5 Rebecca F McLoughlin,2– 4 Teresa M Vella,6 Anthony W Flynn,7 John D Blakey,8,9 Luke Wolfenden,10,11 Mark Hew,12 John W Upham,13,14 Dennis Thomas,2,4 Philip Bardin,15 Anne E Holland1,2,16 1Respiratory Research@Alfred, Monash University, Melbourne, VIC, Australia; 2Centre of Excellence in Treatable Traits, University of Newcastle, Newcastle, NSW, Australia; 3School of Nursing and Midwifery, University of Newcastle, Newcastle, NSW, Australia; 4Hunter Medical Research Institute Asthma and Breathing Program, Newcastle, NSW, Australia; 5Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia; 6Brand and Engagement, Asthma Australia, Brisbane, QLD, Australia; 7Research, Information and Evaluation, Asthma Australia, Melbourne, VIC, Australia; 8Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia; 9Medical School, Curtin University, Perth, WA, Australia; 10Hunter New England Population Health, Wallsend, NSW, Australia; 11School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia; 12Allergy, Asthma & Clinical Immunology, Alfred Health, Melbourne, VIC, Australia; 13Frazer Institute, University of Queensland, Brisbane, QLD, Australia; 14Department of Respiratory Medicine, Princess Alexandra Hospital, Brisbane, QLD, Australia; 15Monash Lung Sleep Allergy & Immunology, Monash University and Medical Centre, Clayton, VIC, Australia; 16Physiotherapy Department, Alfred Health, Melbourne, VIC, AustraliaCorrespondence: Arwel W Jones, Respiratory Research@Alfred, School of Translational Medicine, Monash University, Alfred Centre, Melbourne, VIC, 3004, Australia, Email arwel.jones@monash.eduPurpose: Oral corticosteroids (OCS) are an effective treatment for severe uncontrolled asthma or asthma exacerbations, but frequent bursts or long-term use carry serious and sometimes irreversible adverse effects, or complications such as adrenal insufficiency upon discontinuation. …”
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Developmental dysfunction in a preclinical model of Kcnq2 developmental and epileptic encephalopathy by Miaomiao Mao, Nikola Jancovski, Yafit Kushner, Lucas Teasdale, Phan Truong, Kun Zhou, Samuel Reid, Linghan Jia, Ye Htet Aung, Melody Li, Christopher A. Reid, Sean Byars, Ingrid Scheffer, Steven Petrou, Snezana Maljevic

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New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells by Zélia Silva, João Amorim Rabaça, Vanessa Luz, Rita Adubeiro Lourenço, Mariolina Salio, Alexandra Couto Oliveira, Pedro Bule, Sebastian Springer, Paula Alexandra Videira

“…However, the cytokine cocktail induced a more pronounced IL-12 production. SNA lectin staining analysis demonstrated that the sialic acid profile is significantly altered by sialidase treatment, but not by the cytokine cocktail, which causes only slight sialic acid upregulation. …”
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Enhancing diagnostic outcomes in kidney genetic disorders: the KidGen national kidney genomics study protocol by Amali Mallawaarachchi, Hugh McCarthy, Thomas A. Forbes, Kushani Jayasinghe, Chirag Patel, Stephen I. Alexander, Tiffany Boughtwood, Jeffrey Braithwaite, Aron Chakera, Sam Crafter, Ira W. Deveson, Randall Faull, Trudie Harris, Lilian Johnstone, Matthew Jose, Anna Leaver, Melissa H. Little, Daniel MacArthur, Tessa Mattiske, Christine Mincham, Kathy Nicholls, Catherine Quinlan, Michael C. J. Quinn, Gopala Rangan, Jessica Ryan, Cas Simons, Ian Smyth, Madhivanan Sundaram, Peter Trnka, Laura Wedd, Erik Biros, Zornitza Stark, Andrew Mallett

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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

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A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder by Soha S. Mahdi, Eduarda Caldeira, Harold Matthews, Michiel Vanneste, Nele Nauwelaers, Meng Yuan, Giorgos Bouritsas, Gareth S. Baynam, Peter Hammond, Richard Spritz, Ophir D. Klein, Michael Bronstein, Benedikt Hallgrimsson, Hilde Peeters, Peter Claes

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LLT1 overexpression renders allogeneic-NK resistance and facilitates the generation of enhanced universal CAR-T cells by Shuxian Zhu, Shiyu Zuo, Chuo Li, Xingjie You, Erlie Jiang, Xiaoming Feng, Yuechen Luo

“…This study tested whether the overexpression of Lectin-like transcript 1 (LLT1), an NK cell inhibitory ligand, in T cell receptor (TCR) and HLA-I/II disrupted universal CD38-targeting CAR-T cells could prevent rejection by allogeneic NK cells. …”
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The Metempiricism of Margins: Professor Anthony Aṣiwaju and the Circumference of Knowledge by Toyin Falola

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Ẹlẹ́nu Rírì ati Àmù Ìyá Rẹ̀. by Mọyọ̀ṣọ́rẹ Òkédìjí

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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…BackgroundHuman C-type lectin-like molecule 1 (CLL-1) represents a promising therapeutic target for Chimeric antigen receptor T (CAR-T) cells therapy in the treatment of acute myeloid leukemia (AML). …”
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Demographics of M Dwarf Binary Exoplanet Hosts Discovered by TESS by Rachel A. Matson, Rebecca Gore, Steve B. Howell, David R. Ciardi, Jessie L. Christiansen, Catherine A. Clark, Ian J. M. Crossfield, Sergio B. Fajardo-Acosta, Rachel B. Fernandes, Elise Furlan, Emily A. Gilbert, Erica Gonzales, Kathryn V. Lester, Michael B. Lund, Elisabeth C. Matthews, Alex S. Polanski, Joshua E. Schlieder, Carl Ziegler

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T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy by Linghua Wang, Siqing Fu, Aung Naing, Funda Meric-Bernstam, Carl Morrison, Joud Hajjar, Mingxuan Xu, Anas Alshawa, Bettzy Stephen, Ying Yuan, Jordi Rodon Ahnert, Abdulrazzak Zarifa, Shrutii Sarda, Timothy Looney, Sapna P Patel, Geoffrey M Lowman, Dzifa Yawa Duose, Jeffrey M Conroy, Evan Kwiatkowski

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PSR J1947−1120: A New Huntsman Millisecond Pulsar Binary by Jay Strader, Paul S. Ray, Ryan Urquhart, Samuel J. Swihart, Laura Chomiuk, Elias Aydi, Eric C. Bellm, Kristen C. Dage, Megan E. DeCesar, Julia S. Deneva, Maura A. McLaughlin, Isabella Molina, Teresa Panurach, Kirill V. Sokolovsky

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ارزیابی تاب‌آوری شهری با استفاده از رویکرد عینی و ذهنی در طول طوفان Harvey by سمانه کلیدری, ابوالقاسم صادقی نیارکی, مصطفی قدوسی

“…نتایج رویکرد عینی حاکی از آن است که تاب­آورترین شهر­ها عبارتند از Harris، Austin، Fort Bend، Galveston، Brazoria، Chambers و شهر­هایی با کمترین تاب­آوری عبارتند از Moore، Presidio، Dimmit، Starr، Jasper، Camron است. …”
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Hepatic Steatosis Aggravates Vascular Calcification via Extracellular Vesicle‐Mediated Osteochondrogenic Switch of Vascular Smooth Muscle Cells by Zhao‐Lin Zeng, Zhi‐Bo Zhao, Qing Yuan, Shi‐Qi Yang, Zhen‐Xing Wang, Zuo Wang, Shi‐Yu Zeng, An‐Qi Li, Qian Chen, Guo‐Qiang Zhu, Xin‐Hua Xiao, Guang‐Hua Luo, Hai‐Yan Luo, Jiao‐Yang Li, Xu‐Yu Zu, Hui Xie, Jiang‐Hua Liu

“…Within these toxic vesicles, a protein cargo is identified called lectin galactoside‐binding soluble 3 binding protein (Lgals3bp) that acted as a potent inducer of osteochondrogenic transformation in VSMCs. …”
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Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis by Lan Gao, Susan Brumby, Crystal Man Ying Lee, George Mnatzaganian, Suzanne Robinson, Helen Brown, Rachel Huxley, Anna Peeters, Dan Xu, James Boyd, Sean Randall, Adrienne O’Neil, Sangita Shakya, Sarah Gauci, Anita Shrestha, James Lucas

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Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study by Rajish S. K. Shil, Adam Seed, Nkongho Egbe Franklyn, Brendan F. Sargent, Greta K. Wood, Yun Huang, Katherine C. Dodd, James B. Lilleker, Thomas A. Pollak, Sylviane Defres, Thomas M. Jenkins, Nicholas W. S. Davies, David A. Cousins, Michael S. Zandi, Thomas A. Jackson, Laura A. Benjamin, Ava Easton, Tom Solomon, John R. Bradley, Patrick F. Chinnery, Craig J. Smith, Timothy R. Nicholson, Alan Carson, Rhys H. Thomas, Mark Alexander Ellul, Nicholas W. Wood, Gerome Breen, Benedict Daniel Michael, the COVID-CNS Study Group

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Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We... by Derouicha Matmou, Asma Memou, Yassine Merad, Ayoub Bouzid, Sohaïb Abd-El-Koudous Bouzid, Aissa Brik, Mounia Sakouhi

“…Le critère de jugement principal était l’éva­luation des pratiques d’automédication. La saisie, l’analyse statistique des données et l’édition des résultats ont été réalisées par le logiciel SPSS version 20. …”
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Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We... by Derouicha Matmou, Asma Memou, Yassine Merad, Ayoub Bouzid, Sohaïb Abd-El-Koudous Bouzid, Aissa Brik, Mounia Sakouhi

“…Le critère de jugement principal était l’éva­luation des pratiques d’automédication. La saisie, l’analyse statistique des données et l’édition des résultats ont été réalisées par le logiciel SPSS version 20. …”
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