Visceral Adipose Tissue Inflammation and Vascular Complications in a Rat Model with Severe Dyslipidemia: Sex Differences and PAI-1 Tissue Involvement by Irena Markova, Martina Hüttl, Natalie Gayova, Denisa Miklankova, Kristyna Cerna, Martina Kavanova, Petra Skaroupkova, Sona Cacanyiova, Hana Malinska

“…Regarding low-grade chronic inflammation, HHTg males exhibited increased serum leptin and leukocyte levels, while females had increased serum interleukin-6 (IL-6). …”
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Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis by Meng Gong, Haichao Liu, Zhixiang Liu, Yongshen Wang, Shiyi Qi, Hong Guo, Song Jin

“…BackgroundThe aim of this study was to explore the genetic level association between obesity, lipids, adipokines, and cognitive ability using bidirectional Mendelian randomization (MR) strategies.MethodsSummary data for three obesity indicators [body mass index (BMI), body fat percentage (BFP) and waist-hip ratio (WHR)], three lipid indicators [HDL cholesterol (HDL), LDL cholesterol (LDL) and triglycerides (TG)], three adipokines [circulating leptin (LEP), Agouti-related protein (AgRP) and Adiponectin (APDN)], and four cognitive ability indicators [cognitive function (CF), cognitive performance (CP), simple reaction time (SRT) and fluid intelligence score (FIS)] were collected. …”
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Hypoglycemic effect and the mechanism of action of a polysaccharide from sweet corncob in a high-fat diet and streptozotocin-induced diabetic mice by Xin Wang, Weiye Xiu, Ye Han, Zhili Wang, Yu Luo, Yongqiang Ma

“…SCP-80-I was found to significantly reduce blood glucose and lipid deposition levels in T2DM mice, as well as decrease serum leptin and increase adiponectin secretion. Interestingly, real time-polymerase chain reaction (RT-PCR) and Western blotting results revealed that SCP-80-I could regulate the expression of several glycolipid metabolisms and insulin secretion genes and proteins, including 5’-AMP-activated protein kinase (AMPK), carnitine palmitoyltransferase I (CPT1), and acetyl coenzyme A carboxylase (ACC) in the liver and AMPK, sirtuin 1 (Sirt1), peroxisome proliferator-activated receptorycoactivator-1 (PGC-1α), and uncoupling protein 2 (UCP2) in the pancreas. …”
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Health implications of racial differences in serum growth differentiation factor levels among men with obesity by Siresha Bathina, Virginia Fuenmayor Lopez, Mia Prado, Elliot Ballato, Georgia Colleluori, Maryam Tetlay, Dennis T Villareal, Sanjay Mediwala, Rui Chen, Clifford Qualls, Reina Armamento‐Villareal

“…Serum GDF15, osteocalcin, C‐terminal telopeptide, sclerostin, adiponectin, leptin, estradiol, testosterone, follicle‐stimulating hormone, luteinizing hormone, 25‐hydroxyvitamin D, lipid profile, and hemoglobin A1C (A1C) were measured. …”
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Hidden Metabolic Disturbances in Women with Normal Glucose Tolerance Five Years after Gestational Diabetes by Yvonne Winhofer, Andrea Tura, Anita Thomas, Thomas Prikoszovich, Christine Winzer, Giovanni Pacini, Anton Luger, Alexandra Kautzky-Willer

“…Metabolic parameters were derived from oral and intravenous glucose tolerance tests; furthermore lipid profile, C-reactive protein (CRP), adiponectin, leptin, and glucagon were assessed. Results. Five years postpartum, pGDM had increased glucose concentrations during the OGTT (AUC: 1.12 ± 0.15 versus 1.0 ± 0.12 mol/L * min, P=0.003) and insulin sensitivity was decreased compared to CON (OGIS: 467.2 ± 64.1 versus 510.6 ± 53.1 mL/min * m2, P=0.01). pGDM had lower adiponectin (8.1 ± 2.6 versus 12.6 ± 5.3, P<0.008) but increased waist circumference and CRP compared to CON. …”
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Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women by Veronica Tisato, Paola Secchiero, Gloria Bonaccorsi, Carlo Bergamini, Pantaleo Greco, Giorgio Zauli, Carlo Cervellati

“…The panel of adipokines included interleukin- (IL-) 6, IL-8, IL-1β, adipsin, lipocalin-2/neutrophil gelatinase-associated lipocalin (ngal), TNF-alpha, monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, hepatocyte growth factor, resistin, leptin, adiponectin, and nerve growth factor. Results. …”
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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Ol... by Francis M. Finucane, Stephen J. Sharp, Mensud Hatunic, Alison Sleigh, Ema De Lucia Rolfe, Avan Aihie Sayer, Cyrus Cooper, Simon J. Griffin, David B. Savage, Nicholas J. Wareham

“…Insulin sensitivity was measured with the oral glucose insulin sensitivity (OGIS) model, the leptin: adiponectin ratio (LAR), and the homeostasis model assessment (HOMA). …”
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Glomerulopathy in the KK.Cg-Ay/J Mouse Reflects the Pathology of Diabetic Nephropathy by Stephen P. O'Brien, Mandy Smith, Hong Ling, Lucy Phillips, William Weber, John Lydon, Colleen Maloney, Steven Ledbetter, Cynthia Arbeeny, Stefan Wawersik

“…Compared to KK- controls, 26-week-old KK- mice had elevated HbA1c, insulin, leptin, triglycerides, and cholesterol, and Unx further elevated these markers of metabolic dysregulation. …”
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Angular and CP-Violation Analyses of B-→D⁎+l-ν-l Decays at Hadron Collider Experiments by Daniele Marangotto

“…The B-→D⁎+l-ν-l branching fractions ratio between muon and tau lepton decay modes R(D⁎) has shown intriguing discrepancies between the Standard Model prediction and measurements performed at BaBar, Belle, and LHCb experiments, a possible sign of beyond the Standard Model physics. …”
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A Reappraisal of Women’s Health Initiative Estrogen-Alone Trial: Long-Term Outcomes in Women 50–59 Years of Age by Eric Roehm

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Significados interpersonales en los géneros legislativos: el texto como macropropuesta by Cecilia Serpa

“…Los resultados ponen en evidencia que cada texto construye una compleja red de intercambios de información y de bienes y servicios y que este entramado de fuerzas contribuye para la realización feliz o afortunada (Austin 1962; Searle 1969, 1975, 1989) del macroacto de habla (van Dijk 1979, 1980) y abonan la hipótesis de que el texto —entendido en estos casos como macropropuesta (Martin 1992b)— aparece globalmente modulado, tal como una proposición puede aparecer modulada en el marco de la cláusula. …”
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Leptogenesis in realistic flipped SU(5) by Stephen F. King, George K. Leontaris, Luca Marsili, Ye-Ling Zhou

“…This pattern generally predicts a lightest RH neutrino too light to yield successful leptogenesis, with any lepton-antilepton asymmetry generated from heavier neutrinos being washed out unless special flavour structures are assumed. …”
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TOWARDS IMPLEMENTATION OF INNOVATIVE METHODOLOGIES IN CONSTRUCTION ENGINEERING IN CHILE. A CASE STUDY by PEDRO MUÑOZ, VIVIANA LETELIER, LUMINITA BIBIRE, LUIS MUÑOZ

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Electromagnetic Radiations from Heavy Ion Collision by Payal Mohanty, Sabyasachi Ghosh, Sukanya Mitra

“…In the calculations of interferometry involving dilepton pairs, it is argued that the nonmonotonic variation of HBT radii with invariant mass of the lepton pairs signals the formation of quark gluon plasma in HIC. …”
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Pornography and Speech Act Theory – An In-Depth Survey by Áron Dombrovszki

“…In her paper, Langton – using John L. Austin’s speech act theory – interprets Catharine MacKinnon’s thesis: pornography is a speech that subordinates and silences women. …”
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Effects of Freezing and Thawing Cycle on Mechanical Properties and Stability of Soft Rock Slope by Yanlong Chen, Peng Wu, Qing Yu, Guang Xu

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Finite family groups for fermionic and leptoquark mixing patterns by Jordan Bernigaud, Ivo de Medeiros Varzielas, Jim Talbert

“…The phenomenology of different classes of these ‘simplified models’ can be explored without reference to explicit model-building assumptions, e.g. the nature of flavour symmetry breaking or any additional field content associated to it, and are also capable of explaining hints of lepton non-universality in R K ∗ $$ {\mathcal{R}}_{K^{\left(\ast \right)}} $$ . …”
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Investigating the Source of Planck-Detected AME: High-Resolution Observations at 15 GHz by Yvette C. Perrott, Anna M. M. Scaife, Natasha Hurley-Walker, Keith J. B. Grainge

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Immune Evasion Strategies of Trypanosoma cruzi by Ana Flávia Nardy, Célio Geraldo Freire-de-Lima, Alexandre Morrot

“…It interferes with the antigen presenting function of dendritic cells via an action on host sialic acid-binding Ig-like lectin receptors. These receptors also induce suppression of CD4+ T cells responses, and we presented evidence that the sialylation of parasite-derived mucins is required for the inhibitory effects on CD4 T cells. …”
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Antibodies Recognizing Yersinia enterocolitica Lipopolysaccharides of Various Chemotypes in Synovial Fluids From Patients With Juvenile Idiopathic Arthritis by Katarzyna Kasperkiewicz, Anna S. Świerzko, Mateusz Michalski, Łukasz Eppa, Mikael Skurnik, Zbigniew Żuber, Maciej Cedzyński

“…Furthermore, we confirmed in vitro that Yersinia LPS processing leads to the exposure of its core region and enhanced potency of complement lectin pathway activation.…”
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