Bacterial pathogens dynamic during multi-species infections by Barny, Marie-Anne, Thieffry, Sylvia, Gomes de Faria, Christelle, Thebault, Elisa, Pédron, Jacques

“…Overall, the results indicate that intraspecific competition, cooperation through trophic interaction and toxicity interference contribute to the maintenance of SRP diversity. …”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…While progress has been made in the context of technical solutions and antibody characterization, we argue that initiatives to make best practice behaviors by researchers more feasible, easy, and rewarding are needed. Global cooperation and coordination between multiple partners and stakeholders will be crucial to address the technical, policy, behavioral, and open data sharing challenges. …”
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Mechanically stable polymer networks incorporating polymeric ionic liquids for enhanced conductivity in solid-state electrolytes by Sezer Özenler, Nataliya Kiriy, Upenyu L. Muza, Martin Geisler, Anton Kiriy, Brigitte Voit

“…The aimed for networks were synthesized through the photo-initiated polymerization of a network-forming monomer and a cross-linker, in the presence of lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) and a PIL bearing quaternized imidazolium groups. …”
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The challenges of independence: ontogeny of at-sea behaviour in a long-lived seabird by Delord, Karine, Weimerskirch, Henri, Barbraud, Christophe

“…Naïve juveniles during their first month at sea after leaving their colony exhibited lower foraging effort (greater proportion of time spent sitting on water, longer and more numerous bouts on water, shorter and fewer flying bouts). …”
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Modeling of peatland fire risk early warning based on water dynamics by B. Kartiwa, . Maswar, A. Dariah, . Suratman, N.L. Nurida, N. Heryani, P. Rejekiningrum, H. Sosiawan, S.H. Adi, I. Lenin, S. Nurzakiah, Ch. Tafakresnanto

“…Herein, the observed parameters were climate and dynamics of ground water level and soil moisture, which were monitored using data loggers installed on predefined representative locations and distributed over three blocks of 30 hectares in the palm oil plantation research site. …”
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Syntheses and crystal structures of the cerium-based coordination polymers poly[(acetic acid)bis(μ-5-carboxythiophene-2-carboxylato)bis(μ-thiophene-2,5-dicarboxylato)dicerium(III)]... by Niklas Ruser, Christian Näther, Norbert Stock

“…This IBU is bridged by six TDC2− linkers to nine other IBUs, forming a three-dimensional framework. …”
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FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models by Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Qifeng Qiu, Benjamin F. Vieira, Lydia Schlaefke, Ryan J. Russo, Ya-An Chang, Jin Cui, Monica Yao, Aiyun Wen, Nelson Hsia, Tama Evron, Katy Ovington, Pei-Ni Tsai, Nicholas Yoder, Bo Lan, Reshmii Venkatesan, John Hall, Cody A. Desjardins, Mo Qatanani, Scott Hilderbrand, John Najim, Zhenzhi Tang, Matthew K. Tanner, Romesh Subramanian, Charles A. Thornton, Oxana Ibraghimov-Beskrovnaya, Stefano Zanotti

“…The platform consists of an antigen-binding fragment, highly specific for the human transferrin receptor 1 (TfR1), conjugated to an oligonucleotide via a cleavable valine-citrulline linker. Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder caused by expanded CUG triplets in the DMPK RNA, which sequester splicing proteins in the nucleus, lead to spliceopathy, and drive disease progression. …”
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Development and Validation of an MRI‐Based Radiomics Nomogram to Predict the Prognosis of De Novo Oligometastatic Prostate Cancer Patients by Wen‐Qi Liu, Yu‐Ting Xue, Xu‐Yun Huang, Bin Lin, Xiao‐Dong Li, Zhi‐Bin Ke, Dong‐Ning Chen, Jia‐Yin Chen, Yong Wei, Qing‐Shui Zheng, Xue‐Yi Xue, Ning Xu

“…Model performance was assessed using receiver operating characteristic (ROC) curves, calibration, and decision curve analysis (DCA). Results Eastern Cooperative Oncology Group (ECOG) score, absolute neutrophil count (ANC) and Rad‐score were included in the nomogram as independent risk factors for OS in de novo oligometastatic PCa patients. …”
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New prognostic model in patients with advanced urothelial carcinoma treated with second-line immune checkpoint inhibitors by Ernest Choy, Yohann Loriot, Fabio Calabrò, Cora N Sternberg, Guillermo De Velasco, Daniel Castellano, Roubini Zakopoulou, Aristotelis Bamias, Nicholas James, Axel Merseburger, F Lopez-Rios, Mario Kramer, Kimon Tzannis

“…Background Bellmunt Risk Score, based on Eastern Cooperative Oncology Group (ECOG) performance status (PS), hemoglobin levels and presence of liver metastases, is the most established prognostic algorithm for patients with advanced urothelial cancer (aUC) progressing after platinum-based chemotherapy. …”
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EVALUATION OF THE WIDELY-USED EQUATIONS OF HYDRAULIC LOSS CALCULATION AND CALIBRATION OF THE HAZEN-WILLIAMS EQUATION IN DRIP IRRIGATION LATERALS by Sh. Shafaei, Gh. Zarei, K. Ebrahimi, Sh. Soleimani, M. Shamsi

“…In this case, the calculated hydraulic head loss is lower than the actual hydraulic head loss, and subsequently, the hydraulic pressure at the desired point will be lower than the required value. …”
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Managing Friends and Foes: Sanctioning Mutualists in Mixed‐Infection Nodules Trades off With Defense Against Antagonists by Camille E. Wendlandt, Saumik Basu, Angeliqua P. Montoya, Paige Roberts, Justin D. Stewart, Allison B. Coffin, David W. Crowder, E. Toby Kiers, Stephanie S. Porter

“…Here, we investigate how antagonist attack affects plant ability to manage mutualists with sanctions, in which a plant rewards cooperative mutualists and/or punishes uncooperative mutualists. …”
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The Stability Improvement of Aspergillus fumigatus α-Amylase by Immobilization onto Chitin-Bentonite Hybrid by Ezra Rheinsky Tiarsa, Yandri Yandri, Tati Suhartati, Heri Satria, Bambang Irawan, Sutopo Hadi

“…The CB hybrid was synthesized by bentonite, chitin, and glutaraldehyde as a cross-linker. The free enzyme was immobilized onto CB hybrid using 0.1 M phosphate buffer pH 7.5. …”
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Systemic Diseases in Patients with Congenital Aniridia: A Report from the Homburg Registry for Congenital Aniridia by Jessica Obst, Fabian N. Fries, Maryam Amini, Annamária Náray, Cristian Munteanu, Tanja Stachon, Shweta Suiwal, Neil Lagali, Berthold Seitz, Barbara Käsmann-Kellner, Nóra Szentmáry

“…Therefore, early genetic diagnosis, early systemic checkup, and adequate treatment, as well as cooperation with pediatrists, neurologists, and audiologists, is suggested in congenital aniridia, which should be considered a syndrome and not an isolated ocular disease.…”
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Mass gatherings in Italy: a study from the 2015 Milan Expo by Pietro Marino, Enzo Albergoni, Aida Andreassi, Gianluca Chiodini, Lucia Colombi, Cristina Corbetta, Gabriella Nucera, Marco Salmoiraghi, Alberto Zoli

“…Flexibility, integration and strong cooperation between the pre-hospital settings and hospitals were incorporated into the application of the plan. …”
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Endoscopic Removal of Gastrointestinal Stromal Tumors in the Stomach: A Single-Center Experience by Yingjie Guo, Xue Jing, Jian Zhang, Xueli Ding, Xiaoyu Li, Tao Mao, Zibin Tian

“…In addition, GISTs of two cases were resected using LECS (laparoscopic and luminal endoscopic cooperative surgery) for the extraluminal and intraluminal growth pattern. …”
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A Study on Dust Storm Pollution and Source Identification in Northwestern China by Hongfei Meng, Feiteng Wang, Guangzu Bai, Huilin Li

“…Strengthening regional and international cooperation for transboundary dust management is also emphasized as critical for sustainable mitigation efforts. …”
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Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources by Diana del Cisne Pineda, Gabriel Berlingieri Polho, Yumi Ricucci Shinkado, Gustavo Alves Contado, Nathalia de Souza Crusoe, Vivian Naomi Horita, Joao Carlos Resende, Jamile Almeida Silva, Guilherme Fialho de Freitas, David Queiroz Muniz, Caio V. Suartz, Leopoldo Alves Ribeiro-Filho, Paulo M. Hoff, José Mauricio Mota

“…PSA50 response was associated with no prior docetaxel use and Eastern Cooperative Oncology Group performance status 0 or 1.CONCLUSIONOral cyclophosphamide is a feasible treatment option for patients with mCRPC, particularly in a scenario of limited health care resources.…”
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Hypoxia-inducible factor 1α is required to establish the larval glycolytic program in Drosophila melanogaster by Yasaman Heidarian, Tess D. Fasteen, Liam Mungcal, Kasun Buddika, Nader H. Mahmoudzadeh, Travis Nemkov, Angelo D'Alessandro, Jason M. Tennessen

“…Notably, our study also reveals that the Sima/HIF1α-dependent gene expression program shares considerable overlap with that observed in dERR mutant, suggesting that Sima/HIF1α and dERR cooperatively regulate embryonic and larval glycolytic gene expression.…”
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Students Perceptions, Satisfactions and Challenges on Problem-Based Learning (PBL): A Survey Study Among Final Year Pharmacy Students by Engku Nuraishah Huda E. Zainudin, Fakhira Damia Khaidir, May Khin Soe, Nurul Asyiqin Yusof, Khairool Azizul Mohammad

“…Most felt comfortable participating in discussions (69%), and nearly all students were satisfied with their group members’ cooperation (95.2%). Although, most findings highlight positive aspects of PBL, this study also identified three major challenges in PBL implementation, namely 1) insufficient time for PBL preparation, 2) lack of teamwork, and 3) difficulty in finding adequate reading materials. …”
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Research hotspots and frontiers in the tumor microenvironment of colorectal cancer: a bibliometric study from 2014 to 2024 by Xinran He, Tingyi Xie, Li Shi, Xuyi Kuang, Lei Li, Xingyu Shang, Bo Fu

“…In addition, keyword and cluster analysis showed that immune checkpoint inhibitors, cancer-associated fibroblasts, macrophage polarization, intestinal microbiota, colorectal cancer liver metastasis, drug resistance, scRNA-seq, etc. may be the research hotspots and trends in this field.ConclusionsColorectal cancer and tumor microenvironment research is in the developmental stage, and strengthening international cooperation can help to drive this field forward. The main components and signaling in TME, CRC immunotherapy, colorectal cancer liver metastasis, and new research techniques are the hot research directions in this domain. …”
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