Efficacy and safety of 3D-therapy at HCV-related subcompensated liver cirrhosis (genotype 1b) by P. O. Bogomolov, M. V. Matsiyevich, A. O. Buyeverov, V. D. Beznosenko, Ye. V. Fedosova, M. Yu. Petrachenkova, S. V. Koblov, K. Yu. Kokina, O. S. Kuzmina, N. V. Voronkova

“…To estimate efficacy and safety of 3D mode of interferon­free therapy in patients with subcompensated liver cirrhosis (LC) of HCV etiology (genotype 1b). …”
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Cost-effectiveness analysis of deep brain stimulation for the treatment of alcohol use disorder and alcoholic liver disease by Oluwatofunmi A. Abiola, Collin M. Lehmann, Khaled Moussawi, Hawre Jalal

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The effect of nuclear transcriptional factor κВ activation inhibitor – curcumine on the experimental immune liver disease by I. N. Alekseyeva, N. V. Makogon, S. I. Pavlovich, T. M. Bryzgina, L. I. Aleksyuk, T. V. Martynova, V. S. Sukhina

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Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…These findings confirmed that conditional knockdown of hepatic PCSK9 attenuates liver inflammation following hyperlipidemia induction by modulating multiple signaling pathways; this suggests that targeting PCSK9 knockdown/inhibition with appropriate agents is useful not only for treating hyperlipidemia but also for ameliorating hyperlipidemia-induced liver inflammation.…”
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Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model by Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi

“…The effects of this compound on liver function, however, are unknown. This study was therefore designed to investigate the effects of BA on liver function in high fat-high carbohydrate (HFHC) diet-induced prediabetic rats. …”
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Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury by Jessica M. Herrera, Yun Weng, Tyler J. Lieberthal, Marcus Paoletti, Tammy T. Chang

“…Some studies suggest that ROCK inhibition may serve as a treatment for liver fibrosis. More investigation is needed to understand the role of hepatocyte ROCK signaling in vivo, especially in the context of profibrotic liver injury. …”
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Time Course of the Development of Nonalcoholic Fatty Liver Disease in the Otsuka Long-Evans Tokushima Fatty Rat by Yi-Sun Song, Cheng-Hu Fang, Byung-Im So, Jun-Young Park, Yonggu Lee, Jeong Hun Shin, Dae Won Jun, Hyuck Kim, Kyung-Soo Kim

“…Nonalcoholic fatty liver disease (NAFLD) is considered a hepatic manifestation of metabolic syndrome. …”
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Can fecal calprotectin be used as a biomarker of non-alcoholic fatty liver disease in obese adolescents? by Büşra Tetik Dinçer, Ayşe Merve Usta, Alev Kural, Nazlı Helvacı, Ahmet Uçar, Nafiye Urgancı

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Diagnostic value of optimised real-time sonoelastography in the assessment of liver fibrosis in chronic hepatitis B and C by Katarzyna Kalita, Krzysztof Filipczak, Małgorzata Bieńkiewicz, Wojciech Deroń, Zbigniew Deroń, Anna Piekarska, Anna Płachcińska, Jacek Kuśmierek

Subjects: “…liver fibrosis…”
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Estudiantes universitarios en tiempos de covid-19: clases en línea y vida cotidiana by Claudia Lucy Saucedo-Ramos, Gilberto Pérez-Campos, Claudia Elisa Canto-Maya

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Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate by M. Koziy

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Zearalenone exacerbates lipid metabolism disorders by promoting liver lipid droplet formation and disrupting gut microbiota by Xiao Han, Bingxin Huangfu, Tongxiao Xu, Kunlun Huang, Xiaoyun He

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Therapeutic anti-inflammatory immune potentials of some seaweeds extracts on chemically induced liver injury in mice by Eman Bases, Mostafa M. El-Sheekh, Shimaa M. El Shafay, Rania El-shenody, Mohamed Nassef

“…This work aimed to assess the therapeutic anti-inflammatory immune potentials of the seaweeds Padina pavonia and Jania rubens extracts on carbon tetrachloride (CCL4)-caused liver damage in mice. Our experimentation included two testing regimens: pre-treatment and post-treatment of P. pavonia and J. rubens extracts in CCL4/mice. …”
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Hepatocellular carcinoma risk scores for non-viral liver disease: A systematic review and meta-analysis by Laura Burke, Alexander Hinkson, Vincent Haghnejad, Rebecca Jones, Richard Parker, Ian A. Rowe

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Ameliorative Potential of Tamarindus indica on High Fat Diet Induced Nonalcoholic Fatty Liver Disease in Rats by Suja Rani Sasidharan, Joshua Allan Joseph, Senthilkumar Anandakumar, Vijayabalaji Venkatesan, Chandrasekharan Nair Ariyattu Madhavan, Amit Agarwal

“…Nonalcoholic fatty liver disease (NAFLD), the prevalence of which is rising globally with current upsurge in obesity, is one of the most frequent causes of chronic liver diseases. …”
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Prevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome by Maria Elisa Franciscatto, Juliana Bosso Taniguchi, Raquel Wohlenberg, Isadora Luísa Riedi, Karen Oppermann

Subjects: “…Non-alcoholic fatty liver disease…”
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Thermal ablation enhances immunotherapeutic effect of IP-001 on orthotopic liver cancer in a rat model by Yan Li, Samuel S.K. Lam, Chun Fung Wong, Tomas Hode, David Anderson, Robert C.G. Martin

“…As a member of a new class of polycationic immunoadjuvants that activate multiple immune response pathways, IP-001 can both sequester ablation‐released tumor antigens in situ and independently recruit and stimulate antigen presenting cells (APCs) to induce a potent tumor-specific Th1 type T cell response.Methods An orthotopic HCC rat model is established by implantation of 5 × 106 N1-S1 cells into the left lobe of liver. When tumor size reached 1.0–1.5 cm3, the animals were divided randomly into 4 groups, (1) MWA+IP-001; (2) MWA+saline; (3) sham MWA+IP-001 and (4) sham MWA+saline (n = 5 each group).Results IP001 + MWA treatment significantly suppressed tumor growth in comparison to the other 3 groups. …”
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The Features of Extrahepatic Collateral Arteries Related to Hepatic Artery Occlusion and Benefits in the Transarterial Management of Liver Tumors by Lin Yang, Xiao Ming Zhang, Yong Jun Ren, Nan Dong Miao, Xiao Hua Huang, Guo Li Dong

“…To investigate the extrahepatic collateral arteries related to hepatic artery occlusion (HAO) and to determine its benefits in the transarterial management of liver tumors. Methods and Findings. Eleven patients (7 hepatocellular carcinomas, 3 liver metastases, and 1 with hemangioma) with HAO confirmed with digital subtraction angiography (DSA) were admitted to our hospital. …”
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Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway by Tong Liu, Yujing Xia, Jingjing Li, Sainan Li, Jiao Feng, Liwei Wu, Rong Zhang, Shizan Xu, Keran Cheng, Yuqing Zhou, Shunfeng Zhou, Weiqi Dai, Kan Chen, Fan Wang, Jie Lu, Yingqun Zhou, Chuanyong Guo

“…However, its function in concanavalin A-induced acute liver injury remains uncertain. The aim of the present study was to investigate the functions of shikonin and its mechanism of protection on ConA-induced acute liver injury. …”
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A five-plex Hepatic Oncochip reveals EMT triplet correlated with BAP31 in liver cancer by Youjia Kong, Youjia Kong, Tengfei Zhuang, Xvshen Ding, Xvshen Ding, Sirui Cai, Weijie Ding, Xiaoxiao Zhang, Yubo Sun, Bingquan Zhou, Yuanjie Sun, Shuya Yang, Xiyang Zhang, Xiyang Zhang, Kun Yang, Kun Yang, Dongbo Jiang, Dongbo Jiang

Subjects: “…liver cancer…”
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