Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature by Kyle Kreitman, Satheesh P. Nair, Jiten P. Kothadia

“…We report a case of a 46-year-old female with a history of metastatic lung cancer who presented with acute liver failure after being on crizotinib for two months. …”
Get full text

A Population-Based Cross-Sectional Study of the Association between Liver Enzymes and Lipid Levels by Subrata Deb, Prasanth Puthanveetil, Prashant Sakharkar

“…To examine the association between low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels and liver enzyme functions. Methods. The National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2012 was used to examine the association between liver enzymes and lipid levels amongst adults in the United States. …”
Get full text

Evaluation of the Liver and Pancreatic Functions in Patients with Alcohol-Related Sialadenosis – A Case Control Study by E Elavarasi, Vinothini Gunasekaran, Mohan Thirumal, R Balaji Subramaniyan, Ravi David Austin, S Thirumalai

Subjects: Get full text

Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease. by Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková, Radana Kotalová, Janka Globinovská, Markéta Šafaříková, Lucie Pfeiferová, Hana Zůnová, Lenka Mrázová, Viktor Stránecký, Alena Vrbacká, Ondřej Fabián, Eva Sticová, Daniela Skanderová, Jan Šperl, Marta Kalousová, Tomáš Zima, Milan Macek, Joanna Pawlowska, A S Knisely, Stanislav Kmoch, Milan Jirsa

“…<h4>Patients and methods</h4>Both paediatric (n = 33) and adult (n = 18) patients with cholestatic liver disease of unknown aetiology were eligible. …”
Get full text

Liver and Spleen Stiffness Measurements for Assessment of Portal Hypertension Severity in Patients with Budd Chiari Syndrome by Elton Dajti, Federico Ravaioli, Antonio Colecchia, Giovanni Marasco, Amanda Vestito, Davide Festi

“…Budd-Chiari Syndrome (BCS) is a rare vascular disease of the liver caused by the obstruction of the hepatic venous outflow located from the small hepatic venules up to the entrance of the inferior vena cava (IVC) into the right atrium. …”
Get full text

Correlation of Platelet Indices with Severity of Gastroesophageal Varices in Patients of Liver Cirrhosis: A Research Protocol by Parav Tantia, Sourya Acharya

“…Introduction: In India, liver cirrhosis is a significant public health concern, contributing to 2.95% of total deaths. …”
Get full text

Polymorphism of renin — angiotensin system genes in progression of liver fibrosis in patients with chronic hepatitis C by O. V. Taratina, T. N. Krasnova, L. M. Samokhodskaya, T. N. Lopatkina, V. A. Tkachuk, N. A. Mukhin

“…To estimate relation of polymorphism of genes encoding reninangiotensin system components (AGT G-6A, AGT M235T and ATR1 A1166C) with rate of liver fibrosis progression in patients with chronic hepatitis C (CHC).Material and methods. …”
Get full text

Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis by Teodor Kapitanov, Ulf P. Neumann, Maximilian Schmeding

“…We compare the value of TACE to liver resection for patients with BCLC stage A and B HCC. …”
Get full text

Major Histocompatibility Class II Pathway Is Not Required for the Development of Nonalcoholic Fatty Liver Disease in Mice by Gilles Willemin, Catherine Roger, Armelle Bauduret, Kaori Minehira

“…Single-nucleotide polymorphisms within major histocompatibility class II (MHC II) genes have been associated with an increased risk of drug-induced liver injury. However, it has never been addressed whether the MHC II pathway plays an important role in the development of nonalcoholic fatty liver disease, the most common form of liver disease. …”
Get full text

Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…Aim: to evaluate the frequency of portal vein thrombosis (PVT) and build predictive models of the development of PVT for patients with liver cirrhosis (LC) of A and B/C classes by Child-Pugh.Materials and methods. …”
Get full text

Association of Adverse Perinatal Outcomes with Blood Components Transfusion in Patients with Acute Fatty Liver of Pregnancy by Pan X, Chu R, Qiao X, Zhang X, Li L, Zhang W

“…Prompt identification of patients with high-risk factors is crucial to improve maternal and fetal outcomes.Plain Language Summary: This retrospective study evaluated 146 patients with acute fatty liver of pregnancy and 172 fetuses to determine the effectiveness of blood transfusion therapy and identify predictive risk factors for adverse outcomes. …”
Get full text

Liver Cirrhosis/Severe Fibrosis Is a Risk Factor for Anastomotic Leakage after Colorectal Surgery by Samuel Andreas Käser, Irina Hofmann, Niels Willi, Felix Stickel, Christoph Andreas Maurer

“…Purpose. Liver cirrhosis associated with high perioperative morbidity/mortality. …”
Get full text

Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…In NASH mice, JZG reduced hepatosteatosis, and inflammatory infiltration, and improved mitochondrial morphology and quantity in liver tissues. Additionally, elevated phosphorylation ratio of non-receptor tyrosine kinase c-Src (Src) and reduced phosphorylation ratio of JNK and SH2-containing protein tyrosine phosphatase (SHP-1) were found in both hepatocytes and mice liver tissues treated with JZG versus those with the vehicle.Conclusion: Taken together, JZG could improve mitochondrial dysfunction and reduce lipotoxic liver injury in NASH in vivo and in vitro models. …”
Get full text

Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma by Gorkem Odabas, Metin Cetin, Serdar Turhal, Huseyin Baloglu, A. Emre Sayan, Tamer Yagci

“…Hepatocellular carcinoma is an aggressive malignancy of the liver and is ranked as the sixth most common cancer worldwide. …”
Get full text

Overview of hepatocarcinogenesis focusing on cellular origins of liver cancer stem cells: a narrative review by Jong Ryeol Eun

Subjects: Get full text

Diagnostic and Prognostic Value of Hyperammonemia in Patients with Liver Cirrhosis, Hepatic Encephalopathy, and Sarcopenia (Experts’ Agreement) by M. Yu. Nadinskaia, M. V. Maevskaya, I. G. Bakulin, E. N. Bessonova, A. O. Bueverov, M. S. Zharkova, S. V. Okovityi, A. S. Ostrovskaya, K. A. Gulyaeva, V. T. Ivashkin

“…The Russian Scientific Liver Society selected a panel of seven experts in liver cirrhosis research and management of patients with this disease to make reasoned statements and recommendations on the issue of diagnostic and prognostic value of hyperammonemia in patients with liver cirrhosis, hepatic encephalopathy and sarcopenia.Results. …”
Get full text

Crosstalk between fat tissue and muscle, brain, liver, and heart in obesity: cellular and molecular perspectives by Zixuan Jia, Ziqi Wang, Huixin Pan, Jing Zhang, Qinglu Wang, Caixia Zhou, Jun Liu

Subjects: Get full text

Systematic Sex-Based Inequity in the MELD Score-Based Allocation System for Liver Transplantation in Germany by Leke Wiering, Leke Wiering, Annette Aigner, Marieke van Rosmalen, Brigitta Globke, Brigitta Globke, Tomasz Dziodzio, Nathanael Raschzok, Nathanael Raschzok, Münevver Demir, Wenzel Schöning, Frank Tacke, Petra Reinke, Johann Pratschke, Robert Öllinger, Paul V. Ritschl, Paul V. Ritschl

Subjects: Get full text

Clinical guidelines of the Russian gastroenterological association and the Russian society on study of the liver on diagnostics and treatment of cholestasis by V. T. Ivashkin, Ye. N. Shirokova, M. V. Mayevskaya, Ch. S. Pavlov, O. S. Shifrin, I. V. Mayev, A. S. Trukhmanov

Get full text

Complex Liver Resections for Colorectal Metastases: Are They Safe in the Low-Volume, Resource-Poor Caribbean Setting? by Shamir O. Cawich, Dexter A. W. Thomas, Chunilal Ramjit, Roderick Bhagan, Vijay Naraynsingh

“…Although many authorities suggest that major liver resections should only be carried out in high-volume specialized centres, many patients in the Caribbean do not have access to these health care systems. …”
Get full text