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24401
Conocimientos sobre la lectoescritura emergente y prácticas en las aulas para su promoción: Un estudio con docentes de Educación preescolar en Costa Rica/ Emergent Literacy Knowled...
Published 2017-12-01“…The goal of this program is to promote reading and writing learning among children living in urban-marginalized populations in Argentina. …”
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24402
Pengaruh Timbal (Pb) Terhadap Kadar MDA Serum Tikus Putih Jantan
Published 2014-09-01“…Pb toxicityinhibitsan enzyme that acts as an antioxidant and liver cell damage.<br />The purpose of this study was to observe the effect of lead (Pb) on levels of malondialdehyde (MDA) male whiterats. …”
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24403
Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration
Published 2024-01-01“…Discrimination was improved when CD4 and HIV RNA were added VACS-CCI (C-statistic = 0.79). Liver and kidney disease, congestive heart failure, malignancy, and dementia were negatively associated with CD4 (p-trends all <0.0001).DiscussionAmong PWH and PWoH in VA care, age alone weakly discriminates risk of mortality. …”
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24404
Dietary Thymol Improved Growth, Body Composition, Digestive Enzyme Activities, Hematology, Immunity, Antioxidant Defense, and Resistance to Streptococcus iniae in the Rainbow Trout...
Published 2022-01-01“…TYM at dietary levels of 1.5-2.5 g significantly enhanced liver antioxidant enzyme activity [superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT)], immune components in blood [alternative complement activity (C3), total immunoglobulin (Ig), lysozyme activity, bactericidal activity, and total protein], and in mucus [alkaline phosphatase (ALP), protease activity, lysozyme activity, bactericidal activity, and total protein] compared to other diets (P<0.05). …”
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24405
A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity
Published 2025-01-01“…Abstract Background Agonistic monoclonal antibodies targeting 4-1BB/CD137 have shown preclinical promise, but their clinical development has been limited by severe liver toxicity or limited efficacy. Therefore, a safe and efficient immunostimulatory molecule is urgently needed for cancer immunotherapy. …”
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24406
Hiperurisemia pada Pra Diabetes
Published 2012-09-01“…So that the hyperinsulinemia in the pre-diabetic condition increases the<br />reabsorption of which will lead to hyperuricemia. Urate transporter in the apical membrane of renal tubule known as<br />URAT-1 plays a role in urate reabsorption.…”
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24407
Buffalo meat quality, processing, and marketing: harnessing its benefits and nutraceutical potential
Published 2023-11-01“…In comparison, the endogenous pathway of fatty acid formation through the liver or adipose tissue allows us to enhance the elongation capacity of polyunsaturated n3 fatty acids, vital for human health as precursors of anti-inflammatory prostaglandins. …”
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24408
Effects of in ovo feeding of vitamin C on embryonic development, hatching process, and chick rectal temperature of broiler embryos
Published 2025-01-01“…In conclusion, our data demonstrated that VC accelerated the hatching process and reduced chicks’ rectal temperature, which may be related to the improvement of liver function and changes in metabolism, as indicated by blood biochemical indicators.…”
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24409
OUR EXPERIENCE IN TREATMENT OF ENTEROATMOSPHERIC FISTULAS FORMED AS A RESULT OF MINE-EXPLOSIVE INJURY
Published 2024-10-01“…However, 87% of all penetrating wounds of the abdominal cavity are accompanied by intestinal damage, which in the future can lead to the formation of enteroatmospheric fistulas. …”
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24410
Simulación del nivel de agua para escenarios de inundación. Aplicación a Luján (Buenos Aires, Argentina).
Published 2023-07-01“…Esto permite generar diferentes escenarios de amenaza al representar la superficie susceptible de sufrir inundaciones cuando el río aumenta su nivel de agua en diferentes medidas. En esta línea, el objetivo principal es realizar una caracterización espacial de las inundaciones en Luján a partir de la generación de dos escenarios, considerando datos históricos de eventos de inundación en la ciudad y utilizando como insumo principal un Modelo de Elevación Digital Aerofotogramétrico, puesto a disposición por el Instituto Geográfico Nacional de la República Argentina. …”
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24411
How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects
Published 2025-01-01“…Treatment nonadherence was associated with socioeconomic-related factors of being aged 15– 65 years, living in rural areas, having history of formal education, and having a household size of 2– 6 people. …”
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24412
Abnormalities in Blood Parameters in Athletes Taking Anabolic Androgenic Steroidal Agents; an Observational Clinical Study
Published 2025-01-01“…The purpose of this study was to investigate the adverse effects of the use of AAS by athletes and to determine whether AAS use leads to changes in certain blood parameters.Methods: This is an observational study consisting of two stages. …”
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24413
Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placebo-contro...
Published 2025-01-01“…The trial included a 1-week lead-in, followed by a 4-week double-blind treatment, and a 4-week follow-up. …”
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24414
The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury
Published 2025-01-01“…Multivariate regression identified that the SOFA score, PT, ΔScr, Tbil, chronic liver disease, and Vasopressor use as independent risk factors for persistent severe SA-AKI (P < 0.05). …”
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24415
Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context
Published 2025-02-01“…In a rodent stroke model, NA-1 or Y-3 neuroprotective agents were administered via ICO to evaluate safety and efficacy by assessing neurological deficits, infarct size, neuroinflammatory factors, neuronal apoptosis, and liver/kidney function. Drug concentration in tissues was measured using fluorescence tracing and high-performance liquid chromatography to gauge ICO delivery efficiency. …”
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24416
Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies
Published 2025-02-01“…Primary endpoints were reductions in serum uric acid levels, while secondary outcomes included effects on lipid profile, glycemia, liver enzymes, and treatment tolerability.ResultsIn Cohort 1, QP significantly reduced uric acid levels by 15.2% in males and 13.8% in females, with no significant changes observed in the probiotic group. …”
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24417
Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway
Published 2025-01-01“…We aim to explore whether the regulation of tumor-intrinsic PGAM5 on mitochondria affects tumor-infiltrating immune cells in the microenvironment and whether tumor-intrinsic PGAM5 can be a therapeutic target to enhance the immunotherapy efficacy of hepatocellular carcinoma (HCC).Methods We analyzed the correlation of PGAM5 expression and immune cells infiltration using Gene Expression Omnibus (GEO) and The Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC) data sets based on cibersort algorithm and tumor-tissue arrays from two independent cohorts. …”
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24418
Urbanización de áreas ribereñas del rio Limay en Neuquén y Plottier.
Published 2021-07-01“…Se trata de sectores que se encuentran dentro de la línea de ribera, sobre la planicie de inundación y por tanto están expuestos a las crecidas normales o con recurrencias de 10 años, según definiciones del ente regulador. …”
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24419
The Spectrum of Pulmonary Disease in Patients with HIV Infection
Published 1994-01-01“…Of note, hemolysis, lymphomas, pulmonary embolism, liver disease and dapsone therapy can be associated with elevated LDH in the context of HIV disease. …”
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24420
Efficacy and safety of various drug combinations in treating plaque Psoriasis: A meta-analysis [version 2; peer review: 2 approved]
Published 2025-01-01“…Incidence rate of abnormality in levels of liver enzymes (OR=1.89,9.5% CI 6.69-5.22, P=0.22), nausea (OR=1.28,95% CI 0.77-2.14, P=0.34), headache (OR=1.28,95% CI 0.77-2.14, P=0.58), fatigue (OR=0.89, 95% CI 0.41-1.90, P=0.45).] …”
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