Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ by Yong-Jik Lee, Hyun Soo Kim, Hong Seog Seo, Jin Oh Na, You-Na Jang, Yoon-Mi Han, Hyun-Min Kim

“…The expression of various biomarkers involved in ATP production was estimated through Western blotting, reverse transcription polymerase chain reaction, oxygen consumption rate, enzyme-linked immunosorbent assay (ELISA), fluorescence staining, and Oil red O staining in several cell lines (skeletal muscle, cardiac muscle, liver, macrophage, vascular endothelial, and adipose cells). …”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

“…Patients and methods This study was conducted on 121 HCC cases that were obtained from liver explants from pathology laboratory at Mansoura Gastroenterology center retrospectively in the period between 2006-2017. …”
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常州奔牛机场鸟类群落结构及鸟击防范 by 吴云豪 1 刘 威 2 台德运 1 袁思佳 1 陈 婉 3 胡超超 1, 4 常 青 1

“…危险鸟类分析揭示严重危险鸟类有17种(占鸟类总数的17.17%),其中对飞机飞行危害程度较高的有家鸽(<i>Columba livia domestica)、</i>白鹭<i>(Egretta garzetta)</i>和八哥<i>(Acridotheres cristatellus</i>)等。…”
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Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models by Di Fan, Xin Wang, Xueyuan Ling, Hongbin Li, Lu Zhang, Wei Zheng, Zehui Wu, Lin Ai

“…Biodistribution data revealed high tracer uptake in the liver, small intestine, and stomach, with significant washout from the bloodstream and tumour over time. …”
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The Loge GDR Was Strongly Associated with NAFLD as a Predictor in Normoalbuminuric Patients with Type 2 Diabetes by Ji B, Gao G, Zhao H, Sheng J, Ma X, Shi S, Ban B

“…Baolan Ji,1 Guanqi Gao,2 Hongyan Zhao,2,3 Jie Sheng,2,3 Xuan Ma,2,3 Shuwei Shi,1– 3 Bo Ban1,2 1Department of Endocrinology, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272029, People’s Republic of China; 2Department of Endocrinology, Linyi People’s Hospital Affiliated to Shandong Second Medical University, Linyi, Shandong, 276034, People’s Republic of China; 3School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, 261000, People’s Republic of ChinaCorrespondence: Bo Ban, Department of Endocrinology, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining, Shandong, 272029, People’s Republic of China, Email banbo2011@163.com Shuwei Shi, School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, 261000, People’s Republic of China, Email ssw15689286547@163.comAim: Attenuated insulin-sensitivity (IS) is a characteristic of type 2 diabetes (T2D) and is closely linked to non-alcoholic fatty liver disease (NAFLD). In recent years, many surrogate markers of IS have emerged to predict NAFLD. …”
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PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…Ex vivo biodistribution data showed that the uptake of [18F]TZ4877 was increased 30.6%, 54.3%, 74.3%, and 115.3% in the liver, kidney, pancreas, and thymus of the infected mice, respectively, compared to that in normal control mice, indicating that S1PR1 is involved in the early immune response to bacterial infection. …”
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Branded content en el metaverso. Análisis de las acciones de las organizaciones destacadas en la primera Guía de Metaverso y Branded Content by Belén Moreno-Albarracín

“…Limitación: Se destaca el tamaño reducido de la muestra y, como futura línea de investigación, se propone un estudio de percepción del usuario, evaluando la influencia ejercida por los vínculos virtuales usuario-marca en las respuestas de la audiencia hacia las marcas en el mundo real. …”
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Perioperative estimations of oxygen consumption from LiDCO™plus-derived cardiac output and Ca-cvO2 difference: Relationship with measurements by indirect calorimetry in elderly pat... by Julia Jakobsson, Carl Norén, Eva Hagel, Magnus Backheden, Sigridur Kalman, Erzsébet Bartha

“…Italy), using data collected 2017-2018 during a prospective observational study on perioperative oxygen transport in 20 patients >65 years during epidural and general anaesthesia for open pancreatic or liver resection surgery. Eighty-five simultaneous intra- and postoperative measurements at different perioperative stages were analysed for prediction, parallelity and by traditional agreement assessment.…”
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Evaluation of [Cu]Cu-DOTA and [Cu]Cu-CB-TE2A Chelates for Targeted Positron Emission Tomography with an αβ-Specific Peptide by Sven H. Hausner, David L. Kukis, M. Karen J. Gagnon, Catherine E. Stanecki, Riccardo Ferdani, John F. Marshall, Carolyn J. Anderson, Julie L. Sutcliffe

“…Whereas [ 64 Cu]Cu-DOTA-PEG-A20FMDV2 resulted in increased levels of radioactivity in the liver, [ 64 Cu]Cu-CB-TE2A-PEG-A20FMDV2 did not. Significantly, both 64 Cu-labeled tracers showed unexpectedly high and persistent levels of radioactivity in the kidneys (> 40% injected dose/g at 4 and 12 hours postinjection). …”
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La escritura del archivo: una reflexión desde los estudios literarios by Sofía Criach

“… En las últimas décadas, se ha acrecentado el caudal de textos que ponen el archivo en escena y reflexionan sobre el cultivo de la escritura en las operaciones de investigación. En esta línea, este ensayo propone pensar las relaciones existentes entre el trabajo de archivo y la escritura académica, partiendo de la experiencia disciplinar de los estudios histórico-literarios. …”
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Vocabulario, narración y argumentación en los primeros años de la infancia y la niñez. Una revisión de investigaciones / Vocabulary, narration and argumentation during the first ye... by Celia Renata Rosemberg, Alejandra Menti, Alejandra Stein, Florencia Alam, Maia Migdalek

“…En el marco de una amplia presentación de trabajos de investigación en el tema, el foco de la revisión son los trabajos previos realizados en el marco de la línea de investigación que llevamos a cabo en Argentina con niños de diversos grupos socioculturales. …”
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Autorreportes verbales en voz alta para la identificación de procesos de razonamiento en pruebas estandarizadas / Verbal Self-reporting to Identify Reasoning Processes in Standard... by Armel Brizuela, Karol Jiménez-Alfaro, Nelson Pérez-Rojas, Guaner Rojas-Rojas

“…Finalmente, se concluye con una discusión sobre los resultados acerca de la utilidad de los autorreportes verbales que recaban evidencias de validez para un test y sobre futuras investigaciones en esta línea.   Abstract: Abstract Current standards for assessing the psychometric quality of psychological and educational tests stipulate that one indication required to justify the inferences derived from the application of a test are those related to answering strategies for the test items. …”
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Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…In vitro experiments were conducted with the primary objective of appraising both the expression profile and the precise functional attributes of SMAD3 within the milieu of Liver Hepatocellular Carcinoma (LIHC). Our findings revealed significant variations in SMAD3 expression between cancerous and adjacent normal tissues. …”
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Identification of Genetic Markers of <i>APOM</i> and <i>CYP7A1</i> Genes Affecting Milk Production Traits in Chinese Holstein by Yanan Liu, Zijiao Guo, Junqing Ni, Chendong Yang, Bo Han, Yabin Ma, Jianming Li, Guie Jiang, Weijie Zheng, Dongxiao Sun

“…Our previous study identified the apolipoprotein M (<i>APOM</i>) and cytochrome P450 family 7 subfamily A polypeptide 1 (<i>CYP7A1</i>) genes as candidates for milk traits in dairy cattle, which were significantly up-regulated in liver tissue of Holstein cows between the dry and lactation periods. …”
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Medullary thyroid cancer in MEN2 pediatric/adolescent carriers of RET mutation: genotype/phenotype correlation and outcome in a retrospective series of 23 patients by Guenda Di Benedetto, Ignazio Barca, Laura De Gregorio, Claudia Scollo, Fiorenza Gianì, Federica Martorana, Marco Russo, Francesco Frasca, Gabriella Pellegriti, Gabriella Pellegriti, Giulia Sapuppo

“…Ten patients (52.6%) had a disease event during the follow-up: 2/19 (10.5%) showed biochemical disease, 6/19 (31.6%) lymph node recurrences, and 2/19 (10.5%) distant metastases (50% liver, 50% bone). At the last follow-up, nine MTCs were not cured. …”
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The carbon cost of impaired welfare on sheep farms by L. Lanzoni, M.C. Reeves, K. Waxenberg, R. Ramsey, A.S. Atzori, J. Bell, R.M. Rees, G. Vignola, C.M. Dwyer

“…Total GHG emissions and emission intensities (EI) in kg of CO2 equivalent per kg live weight were compared across the baseline and the scenarios. …”
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Lipid-encapsulated gold nanoparticles: an advanced strategy for attenuating the inflammatory response in SARS-CoV-2 infection by Sanjeevram Dhandapani, Yujeong Ha, Rongbo Wang, Tae Woo Kwon, Ik-Hyun Cho, Yeon-Ju Kim

“…Biochemical analysis at various oral administration concentrations demonstrated that KGS-NE had no adverse effects on the kidney and liver. Conclusions Our findings strongly suggest that oral administering KGS-NE in mice and Syrian hamster models has the potential to effectively mitigate lung inflammation against coronavirus. …”
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Metformin Increases Protein Phosphatase 2A Activity in Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants by Aktham Mestareehi, Xiangmin Zhang, Berhane Seyoum, Zaher Msallaty, Abdullah Mallisho, Kyle Jon Burghardt, Anjaneyulu Kowluru, Zhengping Yi

“…The primary effects of metformin include decreasing glucose production in the liver and decreasing insulin resistance in the skeletal muscle. …”
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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…The molecular tumor volume (MTV), signal-to-noise ratio (SNR), tumor-to-liver activity concentration ratio (TLR) and standardized uptake values (SUV) were analyzed. …”
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Was It an Adrenocortical Adenoma or an Adrenocortical Carcinoma? Limitation of the Weiss Scoring System in Determining the Malignant Potential of Adrenocortical Tumor: Report on Tw... by Cheuk-Lik Wong, Chun-Kit Fok, Yuk-Kit Chan, Vicki Ho-Kee Tam, Lai-Ming Fung

“…Four years later, the patient presented with an abrupt onset of severe hypercortisolism and was found to have a metastatic recurrence in the liver and peritoneum. The patient received a combination of mitotane, systemic chemotherapy, and palliative debulking surgery and succumbed 8.5 years after the initial presentation due to respiratory failure with extensive pulmonary metastases. …”
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