Enseñanza de razonamiento clínico mediante scripts en un entorno virtual de enseñanza y aprendizaje by Silvia Adriana Maffia, María Alejandra Zangara, Eduardo Dreizzen

“…El objetivo general del trabajo fue establecer un método que permita mejorar las habilidades de razonamiento clínico mediante el diseño y desarrollo de una metodología de enseñanza mediante scripts combinada con estrategias de aprendizaje en línea a través del entorno Moodle para alumnos de la carrera de medicina. …”
Get full text

Higher 3-year recurrence-free survival rate in patients with complete pathological remission following neoadjuvant chemotherapy plus immunotherapy for esophageal cancer: a two-cent... by Hai Zhang, Hai Zhang, Hai Zhang, Haiquan He, Qingyi Feng, Bomeng Wu, Ying Chen, Zhenyang Zhang, Linrong Zhou, Cui Li, Wanli Lin, Jiangbo Lin, Jiangbo Lin

“…No significant differences were observed in the incidences of hemoglobin decrease, platelet decrease, liver function damage, elevated serum creatinine, diarrhea, radioactive pneumonia or immunotherapy-related pneumonia, and esophageal perforation. …”
Get full text

A case of subcutaneous metastatic malignant melanoma of the left medial ankle: a case report and review of literature by Lauren Workman, Lauren Fang, Martina Blazevic, Joanna Chen, Richard Simman

“…At 6 months following completion of therapy, metastases were identified in the lungs, vertebra, ribs, and liver. The patient is currently receiving immunotherapy with ipilimumab-nivolumab. …”
Get full text

Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

“…In in vivo experiments, mice challenged with 269ΔSTM0343 experienced greater weight loss, and the bacterial loads in the spleen, liver, and intestines were elevated by fivefold, 30-fold, and 21-fold, respectively, accompanied by more severe pathological damage. …”
Get full text

The efficacy and safety of peroperative statin treatment during coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Yepanchintseva, B.M. Todurov

“…Perioperative statin initiation was associated with decrease in the frequency of postoperative atrial fibrillation and not accompanied by significant changes of liver and kidney markers dysfunction, including group of patients receiving high doses of statins.…”
Get full text

Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients by Nuttinan Nalinthasnai, Ratchainant Thammasudjarit, Tanapat Tassaneyasin, Dararat Eksombatchai, Somnuek Sungkanuparph, Viboon Boonsarngsuk, Yuda Sutherasan, Detajin Junhasavasdikul, Pongdhep Theerawit, Tananchai Petnak

“…Cluster 1 (N = 27) consisted predominantly of males and showed significantly elevated serum liver enzymes and LDH levels. Cluster 2 (N = 370) was characterized by lower chest x-ray scores and higher serum albumin levels. …”
Get full text

Immunological Remission as a Basis for Dose Reduction of Immunosuppressors in Autoimmune Hepatitis: Results of Monocenter Surveillance Study by A. O. Bueverov, S. V. Koblov, P. O. Bogomolov

“…To confirm the diagnosis, a liver biopsy was performed in 17 patients, a histological picture of AIH was detected in all of them. …”
Get full text

“DEMOLIENDO HOTELES”. CONFLICTOS TERRITORIALES Y AMBIENTALES EN MIRAMAR Y NECOCHEA. by Facundo Martin Hernandez

“…Como conclusión, se expone una línea argumental en la que se expresa que estos conflictos representan oportunidades para reivindicar la justicia socio-espacial.…”
Get full text

Análisis de los métodos de enseñanza en los campeonatos intercolegiales de Fútbol by Luis Miguel Basantes Monta, Luis Danilo Parra Calle

“…La muestra estuvo conformada por 20 entrenadores, quienes participaron en una encuesta en línea diseñada y validada para este propósito. El método mixto es ampliamente reconocido como el enfoque más utilizado por los entrenadores en los campeonatos intercolegiales de fútbol, debido a su capacidad para combinar el desarrollo técnico y táctico con la aplicación práctica en el juego. …”
Get full text

“DEMOLIENDO HOTELES”. CONFLICTOS TERRITORIALES Y AMBIENTALES EN MIRAMAR Y NECOCHEA. by Facundo Martin Hernandez

“…Como conclusión, se expone una línea argumental en la que se expresa que estos conflictos representan oportunidades para reivindicar la justicia socio-espacial. …”
Get full text

Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments by Beihui He, Zheng Chen, Yunmeng Nie, Minmin Luo, Sumei Xu, Junbin Yan, Zhiyun Chen

“…According to the TCM treatment principle that the liver and kidney are homologies, the clinical use of SQP in the treatment of nonalcoholic steatohepatitis (NASH) has achieved a good effect. …”
Get full text

Clinical and imaging features of co-existent pulmonary tuberculosis and lung cancer: a population-based matching study in China by Fan Zhang, Fei Qi, Yi Han, Hongjie Yang, Yishuo Wang, Guirong Wang, Yujie Dong, Hongxia Li, Yuan Gao, Hongmei Zhang, Tongmei Zhang, Liang Li

“…Logistic regression results indicated that factors such as BMI, fever, patchy shadow, cavitation, neck or supraclavicular lymph node metastasis, and liver injury favor the diagnosis of APTB-LC over LC alone. …”
Get full text

MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation by Yi Zhang, Qin-shan Li, Hong-lin Liu, Hong-ting Tang, Han-lin Yang, Dao-qiu Wu, Yu-ying Huang, Li-cheng Li, Li-hong Liu, Meng-xing Li

“…Finally, using conditional knockout mice, intestinal lesions and metastatic liver microlesions were greatly reduced in the intestinal knockout MKRN1 group compared to that in the control group. …”
Get full text

Influence of caffeic acid and Bacillus coagulans supplementation on growth, digestive enzymes, immune response, and antioxidant gene expression in common carp (Cyprinus carpio) and... by Seyedeh Shiva Alavinejad, Mehdi Soltani, Seyed saeed Mirzargar, Poulin Shohreh, Ali Taherimirghaed

“…Additionally, expression of genes related to lysozyme, IL-1β, IL-8, TNF-α, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver tissues of treatment groups were upregulated better than CD (P < 0.05). …”
Get full text

Lethal necrotizing granulomatous vasculitis after bariatric surgery and bilateral mammaplasty by O. V. Blagova, D. Kh. Aynetdinova, A. V. Nedostup, N. A. Novikova, Ye. A. Kogan, Yu. V. Lerner, L. V. Kozlovskaya, V. V. Rameyev, N. A. Mukhin

“…Autopsy revealed the signs of vasculitis with involvement of the brain, skin, mediastinal lymphnodes, lungs, as well as the signs of chronic inflammation, atrophy of breast gland lobules, embolization of the focal lymphatics by the implant substance, ulceronecrotic enteritis of defunctioning bowel, severe liver steatosis with the chronic vitamin deficiency. …”
Get full text

Heterogeneidad ambiental y alteraciones antrópicas en comunidades de manglar en el pacífico sur de México by Ameyali Moreno-Martínez, Gustavo Álvarez-Arteaga, María Estela Orozco-Hernández

“…[Metodología]: La selección de los sitios de estudio y muestreo consideró su representatividad espacial, grado de alteración y proximidad a la línea de costa.  Se caracterizó la estructura y biomasa arbórea y se tomaron muestras de suelo a una profundidad de 30 cm para su análisis en laboratorio. …”
Get full text

Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders by Jeffrey A Meyerhardt, Sunil Kumar, Jessica A Zerillo, Aparna Parikh, James M Cleary, Scott Rodig, Benjamin Schlechter, Kimmie Ng, Stephanie K Dougan, Nora Horick, Glenn J Hanna, Andrew L Coveler, Anuj K Patel, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Kent Mouw, Kathleen Pfaff, Thomas A Abrams, Matthew B Yurgelun, Eliezer M Van Allen, S Jennifer Wang, Leah H Biller, Harshabad Singh, Emma L Welsh, Brandon M Huffman, Lestat R Ali, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Jennifer A Chan, Wolfram Goessling, Jeffrey S Wisch, Brendan Reardon, Robert J Mayer, Catherine Del Vecchio Fitz, Charlotte Kuperwasser

“…Long-term responders had HPV-positive tumors, lacked liver metastases, and achieved a radiological complete response.Conclusions Pembrolizumab has durable efficacy in a rare subset of anal cancers. …”
Get full text

High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma by Haopeng Wen, Tengfei Ji, Liteng Lin, Nan Cheng, Kangshun Zhu, Liangqi Cao

“…However, the effect of DNA demethylation enzymes, ten eleven translocation (TET) proteins, has not been comprehensively characterized in liver cancer. In this research, we sought to unravel the linkage of TET proteins with prognosis, immune characteristics and biological pathways in hepatocellular carcinoma (HCC). …”
Get full text

EVALUACIÓN ESPACIAL DE LA RESILIENCIA URBANA FRENTE A INUNDACIONES EN LUJÁN (BUENOS AIRES, ARGENTINA) by Noelia Principi

“…Se destaca la importancia de esta línea de trabajo de la Geografía Aplicada que permite generar información de base importante para los organismos de planificación y gestión en relación a la toma de decisiones espaciales en el marco del ordenamiento territorial…”
Get full text

Intervención multicomponente para la reducción de las brechas en el proceso de atención y control de la hipertensión by Addys María Díaz Piñera, Tullia Battaglioli, Armando Rodríguez Salvá, Esteban Londoño Agudelo, Lisvett González Rodríguez, Patrick Van der Stuyft

“…<br /><strong>Resultados:</strong> reducir las brechas existentes en el proceso de atención al paciente hipertenso, identificar su magnitud en relación a la línea base. <br /><strong>Conclusiones:</strong> el estudio brindará evidencias al Ministerio de Salud Pública cubano y a otros países, especialmente de América Latina, para mejorar el cuidado del paciente con padecimientos crónicos.…”
Get full text