Diagnostic Utility of Serum Ascites Lipid and Protein Gradients in Differentiation of Ascites by Mukhyaprana Prabhu, Rahul Sai Gangula, Weena Stanley

“…The study included 60 patients with ascites of different etiologies (liver cirrhosis, tubercular peritonitis, and malignant ascites). …”
Get full text

Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs by Alana C. Costa, Arquimedes Gasparotto, Jr., Alana A.K. Garcia, Cícero A.C. Pereira, Emerson L.B. Lourenço, Helena P.G. Joaquim

“…Although liver enzymes were elevated at the highest doses, other biochemical and hematological parameters remained unchanged. …”
Get full text

Parametric and non-parametric estimation of reference intervals for routine laboratory tests: an analysis of health check-up data for 260 889 young men in the South Korean military by Taeyun Kim, Hyunji Choi, Sun Min Lee

“…Participants with obesity showed higher RIs for CBC, some liver function tests and some lipid profiles than participants without obesity.Conclusions Using data from healthy, male Korean soldiers in their 20s, we proposed the RIs for CBC and biochemical parameters, comparing parametric and non-parametric estimation. …”
Get full text

Mathematical models of Plasmodium vivax transmission: A scoping review. by Md Nurul Anwar, Lauren Smith, Angela Devine, Somya Mehra, Camelia R Walker, Elizabeth Ivory, Eamon Conway, Ivo Mueller, James M McCaw, Jennifer A Flegg, Roslyn I Hickson

“…One of the significant characteristics of the P. vivax parasite is its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse infections). …”
Get full text

Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence by Ji‐Hua Shi, Wen‐Zhi Guo, Yang Jin, Hua-Peng Zhang, Chun Pang, Jie Li, Pål‐Dag Line, Shui‐Jun Zhang

“…HER2‐targeted treatment is recommended to suppress the HER2‐mediated tumor growth during postoperative liver regeneration.…”
Get full text

Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study by Shan Chen, Yong Yang, Bo Yang, Ming Chen, Kai Zhang, Yi Wang, Lu-Dong Qiao, Bo Zheng, Hong-Feng Guo, Yuan-Jie Niu, Ben-Kang Shi, Wei-Min Yang, Xiao-Kun Zhao, Xiao-Feng Gao

“…Clinical symptoms, physical signs, urinalysis, liver and kidney function, patient records and evaluation of adverse events (AEs) and serious AEs up to day 15 were evaluated for analysis of safety.Results 361 patients were included in the full analysis set, 356 in the safety analysis set and 335 in the per-protocol set (PPS). …”
Get full text

Lactate and Bilirubin Index: A New Indicator to Predict Critically Ill Cirrhotic Patients’ Prognosis by Xiao-Fu Chen, Yuan Zhao, Wei-Zhen Chen, Xin-Tian Shao, Zhi-Ming Huang

“…For predicting 3-year mortality, the model for end-stage liver disease (MELD) score showed better discrimination ability with an area under the curve of 0.726 (95% confidence interval: 0.680–0.771). …”
Get full text

BMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals by Hirokazu Taniguchi, Miho Ueda, Yukiko Kobayashi, Takatomo Shima

“…Abstract This longitudinal observational study aimed to evaluate whether cardiometabolic factors and dietary characteristics are determinants of metabolic dysfunction-associated steatotic liver disease (MASLD) in non-obese individuals (body mass index [BMI] < 25 kg/m²). …”
Get full text

Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury by Nenad Milošević, Marie Rütter, Yvonne Ventura, Valeria Feinshtein, Ayelet David

“…P-Esbp demonstrated an extended half-life time in the bloodstream, and the polymer accumulated significantly in the liver, lungs, and kidneys within 4 h post injection. …”
Get full text

Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression by Jianfeng Peng, Xueying Zhai, Xiaomei Liu, Zhaoqin Huang, Yimeng Wang, Peizhu Wu, Ran Gao, Xiangjiao Meng

“…Subgroup analyses revealed a significant survival advantage with IBP treatment in patients presenting with baseline liver metastases, less than three metastatic organs, and those who were nonsmokers. …”
Get full text

Examining Prenylated Xanthones as Potential Inhibitors Against Ketohexokinase C Isoform for the Treatment of Fructose-Driven Metabolic Disorders: An Integrated Computational Approa... by Tilal Elsaman, Magdi Awadalla Mohamed

“…<b>Background/Objectives:</b> Fructose-driven metabolic disorders, such as obesity, non-alcoholic fatty liver disease (NAFLD), dyslipidemia, and type 2 diabetes, are significant global health challenges. …”
Get full text

A pelvis MR transformer-based deep learning model for predicting lung metastases risk in patients with rectal cancer by Yin Li, Yin Li, Yin Li, Shuang Li, Shuang Li, Ruolin Xiao, Ruolin Xiao, Xi Li, Yongju Yi, Yongju Yi, Liangyou Zhang, Liangyou Zhang, You Zhou, You Zhou, Yun Wan, Chenhua Wei, Liming Zhong, Liming Zhong, Wei Yang, Wei Yang, Lin Yao, Lin Yao, Lin Yao

“…While artificial intelligence (AI) methods have been successful in detecting liver and lymph node metastases using magnetic resonance (MR) images, research on lung metastases is still limited. …”
Get full text

Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary... by Hadar Klein, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, Alon Kaplan, Yoash Chassidim, Yftach Gepner, Matthias Blüher, Uta Ceglarek, Berend Isermann, Michael Stumvoll, Ilan Shelef, Lu Qi, Jun Li, Frank B. Hu, Meir J. Stampfer, Iris Shai

“…After 18 months of lifestyle intervention, both VATcm2 and VAT% loss were significantly associated with decreased triglycerides, HbA1c, ferritin, and liver enzymes, and increased HDL-c levels beyond weight loss (FDR < 0.05). …”
Get full text

Niveles de carga viral plasmática de VIH en pacientes con tratamiento antirretroviral de Villa Clara. by Rafael Abreu Duarte, Yaneisy Valdés Domínguez, María de Lourdes Sánchez Alvarez, Maribel Alonso Ledo, Marlevis Bello Pérez, Adrían Fernández Martínez

“…Hubo un predominio de los pacientes en tratamiento con Tenofovir, Lamivudine, Dolutegravir(TLD) 167(66.8%). La línea de tendencia se encontraba entre los que tenían 400 y 500 cel/mm3. …”
Get full text

Cultura digital en el estudiantado universitario del norte y del sur de México: Una aproximación comparativa by Patricio Sebastián Henríquez Ritchie, Fernando Domínguez Pozos, Galo E. López Gamboa, J. Gabriel Domínguez Castillo

“…A partir de un diseño cuantitativo con alcance descriptivo y comparativo, el instrumento fue piloteado durante el segundo semestre de 2023, en una muestra intencional no representativa del estudiantado universitario que lo contestó de manera asincrónica y en línea. Los resultados muestran contrastes significativos en las personas participantes del noroeste y sureste de México en función de características demográficas (edad), socioeconómicas (escolaridad de madre o padre, trabajo paralelo a sus estudios), tecnológicas (años de experiencia, autoconcepto) y frecuencia de uso. …”
Get full text

Treatment Effect of a Vascular-Disrupting Agent Dynamically Monitored by DWI: An Animal Experimental Study by Danping Huang, Ruimeng Yang, Yong Zou, Hongmei Lin, Xiangdong Xu, Xinhua Wei, Hanzheng Chang, Liqiong Wu, Wenshuang Ding, Wenjie Tang, Xinqing Jiang

“…Methods. 28 New Zealand white rabbit models with VX2 liver tumors were established and were randomly divided into M410 (intravenous injection of M410 at a dose of 25 mg/kg every three days) and control (intravenous injection of saline every three days) groups. …”
Get full text

The Association of Cell-Free LncH19 and miR-29b Expression with the PI3K/AKT/HIF-1/VEGF Pathway in Patients with Diabetic Nephropathy: In Silico Prediction and Clinical Validation by Noha M. Abd El-Fadeal, Basma Osman Sultan, Asmaa K. K. AbdelMaogood, Essam Al Ageeli, Fatma Tohamy Mekhamer, Sherihan Rohayem, Ahmed Shahidy, Nora Hosny, Manal S. Fawzy, Mohammed M. Ismail, Hidi A. A. Abdellatif

“…Diabetic nephropathy (DN) affects about one-third of patients with diabetes and can lead to end-stage renal disease despite numerous trials aimed at improving diabetic management. …”
Get full text

Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis by Flora Magno de Jesus Oliveira, Cassiano Felippe Gonçalves-de-Albuquerque, Isabel Matos Medeiros de Moraes, Patrícia Alves Reis, Vinicius Novaes Rocha, Patrícia Torres Bozza, Adriana Ribeiro Silva, Hugo Caire de Castro Faria Neto

“…Sepsis is characterized by a life-threatening organ dysfunction caused by an unbalanced host response to microbe infection that can lead to death. Besides being currently the leading cause of death in intensive care units worldwide, sepsis can also induce long-term consequences among survivors, such as cognitive impairment. …”
Get full text

Use of the FHTHWA Index as a Novel Approach for Predicting the Incidence of Diabetes in a Japanese Population Without Diabetes: Data Analysis Study by Jiao Wang, Jianrong Chen, Ying Liu, Jixiong Xu

“…MethodsWe collected the data from the NAGALA (NAfld [nonalcoholic fatty liver disease] in the Gifu Area, Longitudinal Analysis) database. …”
Get full text

Caracterización epidemiológica de trabajadores de la salud enfermos de COVID-19. Provincia Cienfuegos, marzo 2020-septiembre 2021 by Arelys Crespo García, Tamara Montenegro Calderón, Salvador Tamayo Muñiz, Mariela García Velázquez, Lourdes Elena Duany Badell, Narciso Águila Rodríguez

“…<p><strong>Fundamento:</strong> los trabajadores de salud son los que se mantuvieron en la primera línea de la respuesta ante la COVID-19, por lo que tuvieron mayor peligro ante situaciones de potencial exposición.…”
Get full text