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24041
Hepatic arterial infusion chemotherapy combined with systemic therapy sequentially or simultaneously for advanced hepatocellular carcinoma
Published 2024-11-01“…Abstract Background and aims The goal of this study was to compare the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) combined with targeted therapy and PD-(L)1 blockade (triple therapy), either sequentially (SE) or simultaneously (SI), in the treatment of Barcelona Clinic Liver Cancer (BCLC) stage C hepatocellular carcinoma (HCC). …”
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24042
Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial
Published 2021-01-01“…However, biomarkers of vascular calcification, including serum bone alkaline phosphatase and kidney injury, including urine neutrophil gelatinase-associated lipocalin (NGAL)/Cr and urine liver fatty acid-binding protein (L-FABP)/Cr, were improved significantly in the gemigliptin treatment group compared with the control group. …”
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24043
Examining the etiology and pregnancy outcomes of 152 critically ill pregnant patients in the Intensive Care Unit
Published 2025-01-01“…Results The results showed that the main obstetric factors leading to ICU admission were pregnancy-related hypertensive disease, postpartum hemorrhage, and acute fatty liver of pregnancy; the non-obstetric factors included either pregnancy complicated by heart disease, sepsis, or malignant tumors. …”
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24044
Actitudes y percepciones de la población de La Habana sobre la COVID-19
Published 2021-12-01“…Métodos: Estudio descriptivo transversal en una población de 2012 habaneros que, de forma anónima y voluntaria, respondieron un cuestionario en línea distribuido en redes sociales entre mayo y junio de 2021. …”
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24045
Relative expression of IL-10 and TNF-α mRNA of kidney and spleen tissues of rat with and without mammary tumor after exposed to alternating current electric field
Published 2023-07-01“…Data were analyzed using the Livak formula, GraphPad Prism 9.0 software, and significance test ANOVA (α = 0.05). …”
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24046
Plasma Diaphanous Related Formin 1 Levels Are Associated with Altered Glucose Metabolism and Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Case Control Study
Published 2022-01-01“…The levels of circulating plasma DIAPH1 and indicators of glucose, insulin, lipid metabolism, liver enzymes, kidney function, sex hormones, and inflammation were measured in 75 patients with PCOS and 77 healthy participants. …”
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24047
Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations
Published 2025-01-01“…The toxicity study revealed that the mice’s behavior, body weight, and organ weights (liver and kidneys) were unaffected by Ferula communis leaf extract administration compared to controls. …”
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24048
The role of diet therapy in insulin resistance in women with polycystic ovary syndrome
Published 2025-01-01“…The study did not include pregnant, lactating women who took hormonal therapy and/or insulin sensitizers during the last 2 months, had liver, kidney, and heart diseases that failed local treatment of hirsutism, with congenital hyperplasia of the adrenal glands, androgen-secreting tumors, Cushing's syndrome. …”
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24049
Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i>
Published 2025-01-01“…These compounds have various pharmacological functions, including anti-tumor, antioxidant, anti-inflammatory, liver-protective, and immune-regulating effects. …”
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24050
MicroRNA-122 protects against interferon-α-induced hepatic inflammatory response via the Janus kinase–signal transducer and activator of transcription pathway
Published 2025-01-01“…Significant overlap in the epidemiology and coinfection of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) has been identified, which accelerates the development of severe liver cirrhosis and hepatocellular carcinoma worldwide. …”
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24051
Anthropometric and Biochemical Correlations of Insulin Resistance in a Middle-Aged Maltese Caucasian Population
Published 2024-01-01“…On the other hand, systolic and diastolic blood pressure, liver transaminases, high-density lipoprotein cholesterol, serum uric acid, ferritin, waist-hip ratio, “A” body shape, thigh circumference, and weight-adjusted thigh circumference all had poor discriminatory power. …”
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24052
Adipose tissue-derived microRNA-450a-5p induces type 2 diabetes mellitus by downregulating DUSP10
Published 2025-02-01“…Abstract Type 2 diabetes mellitus (T2DM) has rapidly increased worldwide, emerging as the fifth leading cause of death. The treatment of T2DM is challenging due to the side effects of oral hypoglycemic drugs and the limited efficacy of long-term insulin therapy, which can lead to insulin resistance (IR). …”
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24053
Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L.
Published 2025-02-01“…The HE staining results indicated that HRLP had protective effect on liver and kidney tissue cells and structure damage in mice. …”
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24054
Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli...
Published 2024-01-01“…After two months of the intervention period, a significant decrease in the activity of liver enzymes was noticed. Furthermore, a significant reduction in prooxidative parameters (TBARS, NO2-, H2O2) and significant elevation in antioxidative parameters such as SOD and GSH were found (p<0.001). …”
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24055
Propuesta técnica – económica para la producción de harina a partir de la valorización de semillas de zapallo (Curcubita ssp)
Published 2024-12-01“…Además, se describió la línea productiva, compuesta por dos unidades: la primera dedicada al acondicionamiento de las semillas y la segunda enfocada en su procesamiento industrial. …”
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24056
Digital subtraction angiography of intrahepatic portal vein as the key visualization for mesoportal shunting in children with extrahepatic portal vein obstruction
Published 2024-03-01“…All 7 patients had high grade. Liver function was normal in all patients, and in none thrombophilia was confirmed. …”
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24057
Emergency department laparotomy for patients with severe abdominal trauma: a retrospective study at a single regional trauma center in Korea
Published 2024-03-01“…The other four patients, who had liver laceration, kidney rupture, spleen injury, and pancreas avulsion, succumbed to the injuries. …”
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24058
Synthesis, Characterization, and Cytotoxicity Research of Sulfur-Containing Metal Complexes
Published 2025-01-01“…In terms of application, the biological activity of complexes (I)–(III) in human cancer cell lines (lung cancer A549, liver cancer SMMC-7721, breast cancer MDA-MB-231, and colon cancer SW480) was tested using the MTS method. …”
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24059
Simultaneous Pheochromocytoma, Paraganglioma, and Papillary Thyroid Carcinoma without Known Mutation
Published 2018-01-01“…Case. 32-year-old male with incidental liver mass during laparoscopy for acute appendicitis. …”
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24060
Aprendizaje Socioemocional en Educación Física: una revisión sistemática en Educación Secundaria
Published 2024-12-01“…Conclusiones: El desarrollo de esta línea de investigación requiere seguir los criterios de calidad analizados en este estudio, mayor profundidad en la descripción y evaluación de la fidelización de las de intervenciones globalizadas que desarrollen las cinco competencias socioemocionales fundamentales. …”
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