Biomedical and candidate SN P markers of chronopathologies can significantly change affinity of ТАТА -binding protein for human gene promoters by D. A. Rasskazov, N. L. Podkolodnyy, O. A. Podkolodnaya, N. N. Podkolodnaya, V. V. Suslov, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko

“…In the [–70; –20] region of promoters of 14 human genes (location of proven binding sites of ТВР), we found 32 known and candidate SNP markers of circadian- rhythm disturbances, including rs17231520 and rs569033466 (both: risk of chronopathologies in liver); rs35036378 (behavioral chronoaberrations); rs549858786 (rheumatoid arthritis with a chronoaberration of IL1B expression); rs563207167, rs11557611, and rs5505 (all three: chronopathologies of the tumor – host balance, blood pressure, and the reproductive system); rs1143627 (bipolar disorder with circadian dependence of diagnosis and treatment); rs16887226 and rs544850971 (both: lowered resistance to endotoxins because of the imbalance between the circadian and immune systems); rs367732974 and rs549591993 (both: circadian dependence of heart attacks); rs563763767 (circadian dependence of myocardial infarction); rs2276109 and rs572527200 (both: circadian dependence of asthma attacks); rs34223104, rs563558831, and rs10168 (circadian optima of treatment with methotrexate and cyclophosphamide); and rs397509430, rs33980857,rs34598529, rs33931746, rs33981098, rs34500389, rs63750953, rs281864525, rs35518301, and rs34166473 (all: neurosensory hearing loss and restless legs syndrome). …”
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Comparative efficacy of hydroxychloride and organic sources of zinc, copper, and manganese on hatching eggs, embryo and hatchlings attributes by Reza Bakhshalinejad, Stephanie Torrey, Elijah G. Kiarie

“…At hatch, 3 male and 3 female chicks were randomly selected from each pen, bled for plasma concentration of minerals and subsequently euthanized for liver and gizzard weight. There were no interactions (P > 0.05) between the breeder age and trace mineral sources or main effects of trace mineral sources on egg components, settable egg percentage, fertility, hatchability, late-embryonic mortality, and the ratio of hatched male to female. …”
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Dalla crescita turistica di un villaggio alla delocalizzazione della sua popolazione: fenomenologia di una relazione gerarchica tra lo stato cinese e la minoranza nazionale wa by Sarah Coulouma

“…Ai margini territoriali della Repubblica popolare cinese, questo villaggio è di fatto una scenografia teatrale predisposta per rispondere alle aspettative e alle rappresentazioni dei visitatori, provenienti dalle città di etnia Han, nei confronti di questa comunità del villaggio, e d’altro lato esso è costretto a subire una relazione gerarchica tra la civiltà Han e questa nazionalità minoritaria. In linea con il lavoro di Liu Tzu-Kai (2013) sull'eredità e le ideologie culturali attuate a Wengding, quelle di Magnus Fiskesjö sulla nazionalità Wa più in generale (2012 e 2015) e uno degli articoli dell’autore che analizzano nel dettaglio la costruzione del turismo a Wengding (Coulouma, 2019), i dati presentati qui confermeranno il fatto che le politiche di conservazione e i dispositivi del turismo di Wengding partecipano all'oggettivazione di una primitività della cultura e della nazionalità Wa. …”
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Growth Performance, Serum Biochemical Profile, Oxidative Status, and Fertility Traits in Male Japanese Quail Fed on Ginger (Zingiber officinale, Roscoe) Essential Oil by Tchoffo Herve, Kana Jean Raphaël, Ngoula Ferdinand, Folack Tiwa Laurine Vitrice, Adoum Gaye, Moussa Mahamat Outman, Ngouozeu Moyo Willy Marvel

“…The serum content in total cholesterol and triglycerides, the liver weight, the serum content in transaminases, and malondialdehyde decreased in treated quails. …”
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Bioinorganic Synthesis of Polyrhodanine Stabilized Fe3O4/Graphene Oxide in Microbial Supernatant Media for Anticancer and Antibacterial Applications by Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Maryam Zarei, Sonia Bahrani, Khadije Yousefi, Wei-Hung Chiang, Aziz Babapoor

“…Also, the cytotoxic effects of the synthesized compounds on the human liver cancer cell line (Hep-G2) were assessed by MTT assay. …”
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LA EDUCACIÓN 4.0 RETOS Y OPORTUNIDADES by Bladimir Botello

“…Concluye enfatizando la necesidad imperativa de un enfoque colaborativo y holístico, en línea con la teoría del aprendizaje colaborativo de Johnson y Johnson, para abordar este desafío educativo y preparar a los estudiantes para un futuro digital sólidamente fundamentado en la teoría pedagógica contemporánea. …”
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Evaluación del uso de la competencia digital en docentes del programa de educación física by Felipe Douglas Barén Zambrano, Alexis Sebastián Torres Hernández, Maira Emerita Castro Suárez

“…Introducción: La evaluación de la competencia digital que demuestran los docentes del programa de educación física, constituye una línea de trabajo priorizada en el sistema educacional del Ecuador. …”
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Método para la determinación del volumen de una muestra de granos de arroz mediante el procesamiento digital de imágenes by M.S. CLEVA, G.M. SAMPALLO, A.O. GONZALEZ THOMAS, C.A. ACOSTA

“…La constante de proporciona- lidad k se determina igualando la expresión dada por el modelo para el volumen de una muestra de n granos en función de L, A y k, con su volumen obtenido experimentalmente por el método de desplazamiento de tolueno. …”
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RETRACTED: A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice by Shireen Mohammad, Sura Al Zoubi, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Nadine Krieg, Bianka Wissuwa, Bianka Wissuwa, Gustavo Ferreira Alves, Gareth S. D. Purvis, Gareth S. D. Purvis, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Andrea Baragetti, Andrea Baragetti, Alberico Luigi Catapano, Alberico Luigi Catapano, Alberico Luigi Catapano, Egle Solito, Egle Solito, Elisabeth Zechendorf, Tobias Schürholz, Wilmar Correa-Vargas, Klaus Brandenburg, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, Muhammad M. Yaqoob, Lukas Martin, Lukas Martin, Christoph Thiemermann

“…HFD-fed mice for 12 weeks caused obesity, an impairment in glycemic regulations, hypercholesterolemia, microalbuminuria and steatohepatitis, all of which were attenuated by Peptide 19-2.5. The liver steatosis caused by feeding mice a HFD resulted in the activation of nuclear factor kappa light chain enhancer of activated B cells (NF-ĸB) (phosphorylation of inhibitor of kappa beta kinase (IKK)α/β, IκBα, translocation of p65 to the nucleus), expression of NF-ĸB-dependent protein inducible nitric oxide synthase (iNOS) and activation of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome, all of which were reduced by Peptide 19-2.5. …”
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A comparative analysis in monitoring 24-hour urinary copper in wilson disease: sampling on or off treatment? by Isabelle Mohr, Patrick Lamade, Christophe Weber, Viola Leidner, Sebastian Köhrer, Alexander Olkus, Matthias Lang, Andrea Langel, Patrischia Dankert, Melanie Greibich, Silke Wolf, Holger Zimmer, Patrick Michl, Aurélia Poujois, Karl Heinz Weiss, Uta Merle

“…The levels of the biochemical markers liver and copper metabolism remained stable over the 12-month observation period for all patients. 24 h-UCE off-therapy significantly decreased from T0 to T2 (p = 0.03), whereas no statistically significant differences were detected for 24 h-UCE after therapy. …”
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Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems by Nhat Minh Phan, Thi Hong Tuoi Do, Le Thanh Tuyen Nguyen, Trong Tuan Nguyen, Quoc Luan Ngo, Trong Duc Tran, Quan Hien Nguyen, Bui Linh Chi Huynh, Diep Xuan Ky Nguyen, Trong Dat Bui, Dinh Tri Mai, Tan Phat Nguyen

“…The study aims to determine the hepatoprotective effect of n-hexane, ethyl acetate, and methanol extracts of the leaves and stems of two Cleome species against carbon tetrachloride- (CCl4-) induced liver toxicity both in vitro using human hepatoma (HepG2) cells and in vivo in rats as well as the hepatoprotective property of all isolated compounds on HepG2. …”
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Biochemical characteristics, genetic variants and treatment outcomes of 55 Chinese cases with neonatal intrahepatic cholestasis caused by citrin deficiency by Juan Li, Jintao Duan, Shuli He, Ying Li, Meifen Wang, Chengjun Deng

“…In long term follow-up, 2 cases developed FTTDCD, 8 cases had special dietary habits, and 1 case died from cirrhosis.ConclusionsNICCD showed more severe impairments in liver, coagulation, and metabolic function than INC. …”
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Toxicity Study of Trichlorfon Insecticide Towards Nile Tilapia Oreochromis sp. by E. Supriyono, P.R. Pong-Masak, P.E. Naiborhu

“… The study was conducted to study toxicity and accumulation levels of trichlorofon in Nile tilapia (Oreochromis sp.) in weight of 2.54±0.79 g.  Experiment was diveded into three steps, i.e., (1) determination of toxicity range for 48 hours, (2) devinitive test for 96 hours, and (3) bioaccumulation test for 96 hours.  …”
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Comportamiento del cáncer de mama en la provincia de Cienfuegos. Quinquenio 2007-2011 by Lidia Torres Ajá

“…<strong>Fundamento</strong>: el cáncer de mama representa la primera localización y segunda causa de muerte por tumores malignos en el sexo femenino en Cuba, lo cual ha hecho que sea considerado un problema de salud y una línea priorizada de investigación por parte del Ministerio de Salud Pública. …”
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Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica by Pedro Martínez Gómez

“…Finalmente, un análisis funcional de la biotecnología en general y la obtención de plantas modificadas en particular, puede mejorar su percepción social en línea con la mayor entrañabilidad de la tecnología, sería también de interés de cara a neutralizar el rechazo inicial de la tecnología.    …”
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The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…JQ1-mediated loss of adipose tissue mass was not associated with systemic inflammation or with lipid accumulation in muscle and liver. JQ1 administration did not impinge on skeletal muscle metabolism and oxidative capability, as shown by the lack of significant impact on mitochondrial mass and biogenesis. …”
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Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus by Manoj Kumar Sarma, Andres Saucedo, Suresh Anand Sadananthan, Christine Hema Darwin, Ely Richard Felker, Steve Raman, S. Sendhil Velan, Michael Albert Thomas

“…Correlation analyses indicated associations between IMCL U.I. and various metabolites in muscles with liver, pancreas, and abdominal fat estimates in T2DM. …”
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Factors associated with pulmonary complications after hepatectomy and establishment of nomogram: A real-world retrospective study by Kunyu Han, Hui Liu, Ruiping Bai, Jiarui Li, Linjuan Zhang, Rui An, Di Peng, Jiamin Zhao, Mengwen Xue, Xin Shen

“…Background and Aims: Hepatectomy is currently the most effective way to treat liver diseases, and its safety has observably improved. …”
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Un nuevo sistema de diseño de embuticiones en láminas de acero para maximizar resistencia de losas compuestas A new system for designing embossments in steel sheets to increase com... by Melchor López Ávila, Rafael Larrúa Quevedo, Carlos Recarey Morfa

“…Aplicando el método propuesto obtuve un sistema de embuticiones tecnológicamente posible y con un coste mínimo de inversiones para una línea industrial de láminas de perfilado abierto.…”
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Desarrollo de nuevos diseños vegetales: Mejora genética vs transformación genética y edición génica by Pedro Martínez Gómez

“…Finalmente, un análisis funcional de la biotecnología en general y la obtención de plantas modificadas en particular, puede mejorar su percepción social en línea con la mayor entrañabilidad de la tecnología, sería también de interés de cara a neutralizar el rechazo inicial de la tecnología.    …”
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