Statin prescriptions and progression of advanced fibrosis risk in primary care patients with MASLD by Andrew D Schreiner, William P Moran, Jingwen Zhang, Patrick D Mauldin, Justin Marsden, Mulugeta Gebregziabher, Chelsey A Petz, David G Koch, Chloe Bays

“…Objective We aimed to determine the association of statins with progression to a high risk for advanced fibrosis in primary care patients with metabolic dysfunction-associated steatotic liver disease (MASLD).Design This retrospective cohort study of electronic health record data included patients with MASLD and an initial low or indeterminate risk for advanced fibrosis, determined by Fibrosis-4 Index (FIB-4) score (<2.67). …”
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Clinical features and outcomes of pseudolithiasis induced by ceftriaxone in Chinese children: a single-center observational study by Chen Jin, Chen Jin, Wen-Li Xiu, Wen-Li Xiu, Yao Liu, Yao Liu, Xi-Wei Hao, Qian Dong, Qian Dong

“…Serum analysis revealed distinct liver and kidney function markers in the PL group, including lower levels of total bile acids, adenosine deaminase, and lactate dehydrogenase, and higher creatinine levels (all p < 0.05). …”
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Prevalence and clinical profile of hepatitis C virus infections in multitransfused thalassemic patients in the capital twin cities of Pakistan by Z. Z. Piracha, U. Saeed, R. Uppal, M. R. Uppal, A. Ahmad Khan, M. Abdullah, K. Mari, A. Basra, S. S. Gilani, M. N. Tariq, D. U. Ozsahin, B. Uzun, I. Ozsahin

“…Additionally, hepatomegaly was prevalent in 82.20% of HCV-positive thalassemic patients, featuring an average liver size increase of 4.33 cm. Splenomegaly was evident in 67.12% of HCV-positive thalassemic patients, with an average spleen size augmentation of 4.46 cm. …”
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Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact by Liuqingqing Liu, Xinyao Li, Xianxiang Luo, Xiao Wang, Linjia Liu, Zixi Yuan, Cuizhu Sun, Hao Zheng, Elvis Genbo Xu, Fengmin Li

“…PAEs accumulated in the juvenile fish in the order of brain > liver > gut > muscle, with DEHP showing the highest brain concentrations (23.2 ± 2.98 μg g−1). …”
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Knowledge, Attitude, and Practice towards Hepatitis B Virus among Pregnant Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Hospital, Northwest... by Teklay Gebrecherkos, Getu Girmay, Mulualem Lemma, Markos Negash

“…Majority of the respondents (85.87%) had never screened for HBV, and only 28.5% of the participants believed that hepatitis B can cause liver cancer. In multivariable analysis, residence, income, and educational level were associated with mean score knowledge and attitude. …”
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Exploring the attitudes of solid organ transplant recipients towards COVID-19 shielding communications and the language of ‘clinically extremely vulnerable’: a qualitative study in... by Jason Ali, Dominic Summers, Abbie E Greig, Kirsten L Rennie

“…This qualitative study explores the attitudes of SOT recipients towards COVID-19 shielding communications and the language used.Methods Semistructured interviews were conducted with 43 adult heart, liver and kidney transplant recipients in England between January 2022 and May 2023. …”
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Subchronic Toxicity Study of Alternanthera philoxeroides in Swiss Albino Mice Having Antioxidant and Anticoagulant Activities by Shahad Saif Khandker, Morshed Alam, Forhad Uddin, Ummay Mahfuza Shapla, Nafisa Lubna, Tanusree Amy Mazumder, Mahfuza Marzan, Milon Mondal, Md Ibrahim Khalil, Nurul Karim, Md Salman Shakil, Md Sakib Hossen

“…Following that, the in vivo toxicological effects of methanolic extracts of A. philoxeroides using different doses on the kidney, heart, lung, liver, stomach, brain, and blood of female Swiss Albino mice were investigated. …”
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New Insights Into Hepatic Impairment (HI) Trials by Sebastian Haertter, Maximilian Lobmeyer, Brian C. Ferslew, Pallabi Mitra, Thomas Arnhold

“…ABSTRACT Hepatic impairment (HI) trials are traditionally part of the clinical pharmacology development to assess the need for dose adaptation in people with impaired metabolic capacity due to their diseased liver. This review aimed at looking into the data from dedicated HI studies, cluster these data into various categories and connect the effect by HI with reported pharmacokinetics (PK) properties in order to identify patterns that may allow waiver, extrapolations, or adapted HI study designs. …”
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Immuno-Inflammatory Characteristics in Low Severity COVID-19 Patients with Digestive Symptoms by Caihan Duan, Shengyan Zhang, Jian Wang, Wei Qian, Chaoqun Han, Xiaohua Hou

“…Multiorgan function and immuno-inflammatory characteristics were analyzed for all of the three groups. Results. Mild liver damage and activation of the immuno-inflammatory system were the most common abnormalities observed in patients with mild COVID-19 symptoms but no significant differences were found (P>0.05). …”
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La Agencia de los Estados Unidos para el Desarrollo Internacional (USAID) como arma contra la colaboración médica internacional de Cuba by Yiliam Jiménez Expósito, Omar Stainer Rivera Carbó

“…El antecedente de este nuevo programa es uno similar financiado por el gobierno de Trump, en 2019, aunque este cuenta con 1 millón de dólares adicionales. Como la principal línea de mensaje que se emplea contra los convenios médicos cubanos internacionales, es que violan los derechos humanos al promover el trabajo esclavo, priorizan la búsqueda de testimonios para sustentar dicha campaña. …”
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Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i> by Nikolay V. Volozhantsev, Maria A. Makarova, Alena S. Kartseva, Marina V. Silkina, Valentina M. Krasilnikova, Egor A. Denisenko, Alexander I. Borzilov, Victoria V. Firstova

“…The introduction of Dep_kpv74 at the therapeutic dose (10 μg/mouse) or at a 10-fold higher dose did not lead to reliable changes in bloodstream cell content compared with the reference values of intact mice. …”
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Toxicological Characterization of Six Plants of the Beninese Pharmacopoeia Used in the Treatment of Salmonellosis by Boris Legba, Victorien Dougnon, Esther Deguenon, Jerrold Agbankpe, Maximin Senou, Alidah Aniambossou, Carène Gbaguidi, Kevin Sintondji, Lamine Baba-Moussa, Jacques Dougnon

“…Histological sections were performed on the liver and kidneys to confirm hematological and biochemical data. …”
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Clinical Features and Outcomes of Repeated Endoscopic Therapy for Esophagogastric Variceal Hemorrhage in Cirrhotic Patients: Ten-Year Real-World Analysis by Jia-li Ma, Ling-ling He, Ping Li, Yu Jiang, Ju-long Hu, Yu-ling Zhou, Xiu-xia Liang, Hong-shan Wei

“…Out of 2665 patients with liver cirrhosis and variceal hemorrhage selected from our medical center between September 2008 and December 2017, a total of 1342 patients were included for analysis. …”
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Effect of Intervention of Vaccination and Treatment on the Transmission Dynamics of HBV Disease: A Mathematical Model Analysis by Firaol Asfaw Wodajo, Temesgen Tibebu Mekonnen

“…Since people do not give attention, it will develop into cirrhosis and hepatocellular carcinoma that leads to liver transplantation and death. This nature of HBV disease motivated us to perform this work. …”
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Eco-friendly synthesis of chitosan NPs from Fioria vitifolia (L.) L: Potential to antibacterial, antioxidant, cytotoxicity properties of HepG2 cells and their evaluation of safety... by Mohamed Imath, Chinnasamy Ragavendran, Chinnaperumal Kamaraj, Ramalingam Karthik Raja, Gholamreza abdi

“…The aim of present study was examined antibacterial, antioxidant, antibiofilm and cytotoxicity of liver cancerous cells using Fioria vitifolia mediated chitosan nanoparticles (FV-CNPs). …”
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超声造影定量分析评估门静脉癌栓对肝癌血流动力学的影响

“…【方法】 回顾性分析７例ＨＣＣ合并ＰＶＴＴ和１４例ＨＣＣ未合并ＰＶＴＴ患者的超声造影动态图像，以ＳｏｎｏＬｉｖｅｒＴＭ定量软件进行分析，获得肝癌与周围肝实质的时间－强度曲线，最大峰值强度（ＩＭＡＸ ）、上升时间（ＲＴ ）、平均渡越时间（ ＭＴＴ ）、达峰时间（ ＴＴＰ）分别于组内及组间进行比较。…”
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Acute Coronary Syndrome in Acute Myeloid Leukemia with Maturation Accompanying Megakaryocytic Differentiation by Kentaro Odani, Junya Abe, Yoshiaki Tsuyuki, Soshi Yanagita, Kazuya Shiogama, Mitsuhiro Tachibana, Yutaka Tsutsumi

“…No features of myelofibrosis were seen in the 100% cellular marrow. In the endocardium, liver, lymph nodes, and bone marrow, megakaryocytic cells (CD42b/CD61+, MPO-) were distributed, while the small-sized blastic cells in the blood and tissues predominantly expressed MPO. …”
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Influence of long-term supplementation of a formulated botanical blend on growth performance and carcass traits in feedlot steers by Thiago Lauro Maia Ribeiro, Becca B. Grimes Francis, Erin R. DeHaan, Cassidy R. Ross, Justin J. Delver, Forest L. Francis, Jeff S. Heldt, Emma H. Wall, Warren C. Rusche, Zachary K. Smith

“…No differences were noted for any carcass measurements or categorical carcass outcomes, nor lung or liver health outcomes (p≥0.15). Conclusion The use of CCG had no influence on cumulative growth performance responses. …”
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Multiple rare abdominal aortic branch variations in the case of a centenarian woman. Case report and review of the literature by Michela Vincis, Claire Lewis, Denis Barry, Marcello Trucas

“…Results: A ptotic arrangement of the liver, pancreas, stomach and gall bladder displacement, and multiple rare aortic branch variants were identified, including variations in the inferior phrenic arteries, a long hepatosplenic trunk, a long cystic artery originating from the gastroduodenal artery, the anterior origin of the right renal artery adjacent to the superior mesenteric artery, and the bilateral absence of the ovarian arteries. …”
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Integrated serum pharmacochemistry, pharmacokinetics, and network analysis to explore active components of BuShao Tiaozhi Capsule on hyperlipidemia by Ruiyin Tang, Guanlin Xiao, Yanchang Liu, Dezheng Jia, Zhihao Zeng, Canchao Jia, Dongmei Li, Yangxue Li, Jieyi Jiang, Sumei Li, Xiaoli Bi

“…In vivo experiments showed that BSTZC and its active components could effectively alleviate lipid metabolism disorders and liver injury, with obvious lipid-lowering effects. …”
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