The small GTPase MRAS is a broken switch by Gabriela Bernal Astrain, Regina Strakhova, Chang Hwa Jo, Emma Teszner, Ryan C. Killoran, Matthew J. Smith

“…Acquisition of NMR spectra from isotopically labeled MRAS in live cells validated the GTPase remains fully GDP-loaded, even a supposed activated mutant. …”
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Extracellular viral microRNAs as biomarkers of virus infection in human cells by Cheryl Chan, Joanne Xin Yi Loh, Wei-Xiang Sin, Denise Bei Lin Teo, Nicholas Kwan Zen Tan, Chandramouli Nagarajan, Yunxin Chen, Francesca Lorraine Wei Inng Lim, Michael E. Birnbaum, Rohan B.H. Williams, Stacy L. Springs

“…Here, we show that extracellular viral microRNAs (viral exmiRs) are cell-free candidate biomarkers of live, latent, and reactivated virus infections, achieving fast (under 1 day) and sensitive (30 attomolar [aM]) detection by quantitative real-time reverse transcription PCR (real-time RT-qPCR). …”
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Traumatic Uterine Rupture in Second Trimester: Two Departments, Two Patients, Two Survivors by Kaggwa H, Deogratious E, Ndiwalana BR, Luweesi H, Kaduyu P

“…Uterine rupture due to trauma often results from high-impact blunt abdominal trauma such as motor vehicle accidents, falls and domestic violence, and it is most common in the third trimester. …”
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Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD by Pritha Majumder, Biswanath Chatterjee, Khadiza Akter, Asmar Ahsan, Su Jie Tan, Chi-Chen Huang, Jen-Fei Chu, Che-Kun James Shen

“…Results We demonstrate here that brief mGluR1 activation-mediated dephosphorylation of pFMRP (S499) results in the dissociation of FMRP from TDP-43 and handover of TDP-43/Rac1 mRNA complex from the dendritic transport track on microtubules to myosin V track on the spine actin filaments. …”
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Present(ed) bodies, absent agency: “patients’ perspectives” at the Museum Vrolik of the body and medicine by Azia Lafleur

“…To move forwards from here, persons with disabilities, illness, bodily differences, impairment and injury need to be included and recognized in their capacity as knowers, as having vital embodied knowledge via their lived experience, as narrators and subjects in the stories that are told.…”
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Analysing the Demography and Migration Related Challenges within the Internal Periphery of South-Heves by Tunde Bogardi

“…I have conducted an empirical research amongst high-school students living and studying at South-Heves, focusing on issues such as whether the high-school age-group of this classic periphery is considering migration; if so, then what are the reasons, destinations, and as an important question from the aspect of the national strategy as well, how could these young people who are longing to go elsewhere manage their lives here, and how could we make them stay in their homeland (in a narrow sense). …”
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Mettre l’intime en bande dessinée. Un dialogue avec Léna Merhej et Noémie Honein by Michela De Giacometti, Laura Odasso

“…Originally born as a publishing platform to support works from this first group of artists, the magazine soon transformed into a collective and broadened its horizons to include comics made by artists from the Arab world and beyond. …”
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Extracellular electron transfer genes expressed by candidate flocking bacteria in cable bacteria sediment by Jamie J. M. Lustermans, Mantas Sereika, Laurine D. W. Burdorf, Mads Albertsen, Andreas Schramm, Ian P. G. Marshall

“…ABSTRACT Cable bacteria, filamentous sulfide oxidizers that live in sulfidic sediments, are at times associated with large flocks of swimming bacteria. …”
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Treatment of Sarcoptic Mange in Wombats With Topical Moxidectin by Hayley J. Stannard, Marie B. Wynan, Ray J. Wynan, Amanda Cox, Howard Ralph, Gregory S. Doran

“…ABSTRACT Sarcoptic mange is a debilitating disease affecting free‐living/wild bare‐nosed wombats (Vombatus ursinus). …”
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Impacts psycho-sociaux des espaces verts dans les espaces urbains by Sandrine Manusset

“…We did it under the guidance of Plantes et Cités in 2010, with the aim of gathering present-day knowledge about the positive impact of vegetation in urban areas, on human health, well-being and social dynamics. We wish here to presenter the social and psychological impacts of the green spaces, put evidence within a global vision of the environmental impacts, economical, sociological and cultural of the vegetal in the urban space, stemming from the analysis of 30 references chosen among a first bibliographical bottom of 104 documents and international works, in ecology, town planning, sociology and psychology, constituted by Plantes et Cités. …”
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La nature en privilège : de l’effet des populations citadines aisées sur les paysages et la flore du Cœur vert de la Randstad Holland by Fabien Roussel

“…The hygrophilous flora, which meets the conditions of wetlands and therefore the challenges of preserving biodiversity, is found in the areas furthest from the conurbation, where more modest inhabitants live. …”
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Bumblebee social learning outcomes correlate with their flower-facing behaviour by Yuyi Lu, Zhenwei Zhuo, Mark Roper, Lars Chittka, Cwyn Solvi, Fei Peng, Ying Zhou

“…Two groups of bumblebees observed live conspecifics foraging from either blue or yellow flowers during a single foraging bout, and were subsequently tested for their socially learned colour preferences. …”
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Human-Gorilla and Gorilla-Human: Dynamics of Human-animal boundaries and interethnic relationships in the central African rainforest by Takanori Oishi

“…The Baka hunter-gatherers of the southeast Cameroon–Congo border regions live with their Bakwele farming neighbors. They regard the Bakwele as gorilla–humans that may be reincarnated as gorillas after death. …”
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Approaching maximum resolution in structured illumination microscopy via accurate noise modeling by Ayush Saurabh, Peter T. Brown, J. Shepard Bryan IV, Zachary R. Fox, Rory Kruithoff, Cristopher Thompson, Comert Kural, Douglas P. Shepherd, Steve Pressé

“…Such methods therefore suffer from high-frequency artifacts, user-dependent choices of smoothness constraints making assumptions on biological features, and unphysical negative values in the recovered fluorescence intensity map. …”
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The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole. by Marie Seveno, Manon N Loubens, Laurence Berry, Arnault Graindorge, Maryse Lebrun, Catherine Lavazec, Mauld H Lamarque

“…We had previously identified the serine-threonine phosphatase PP1 as an essential enzyme required for the rupture of the surrounding vacuole. Here, we address its precise positioning and function within the egress signaling pathway by combining chemical genetics and live-microscopy. …”
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The interplay of trophic interactions and game dynamics gives rise to life-history trade-offs, consistent personalities, and predator–prey and aggression power laws by Mohammad Salahshour

“…Aggressive individuals tend to live faster, more reproduction-focused lives, whereas nonaggressive individuals favor slower, longer-lived strategies. …”
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Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development by Zhijie Hu, Yuqi Zhang, Renfei Cai, Qiuju Chen, Haiyan Guo, Danjun Li, Weidong Lin, Hongxi He, Haibo Wu, Yali Liu, Bin Li, Qianwen Xi, Hongyuan Gao, Jian Zhang, Qifeng Lyu, Yanping Kuang, Xuefeng Lu

“…Abstract The precise mechanisms behind early embryonic arrest due to sperm‐related factors and the most effective strategies are not yet fully understood. Here, we present two cases of male infertility linked to novel TDRD6 variants, associated with oligoasthenoteratozoospermia (OAT) and early embryonic arrest. …”
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Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers by Pedro Lobos, Barbara Bruna, Alex Cordova, Pablo Barattini, Jose Luis Galáz, Tatiana Adasme, Cecilia Hidalgo, Pablo Muñoz, Andrea Paula-Lima

“…We reported previously that amyloid-β peptide oligomers (AβOs) produce aberrant Ca2+ signals at sublethal concentrations and decrease the expression of type-2 ryanodine receptors (RyR2), which are crucial for hippocampal synaptic plasticity and memory. Here, we investigated whether the antioxidant agent astaxanthin (ATX) protects neurons from AβOs-induced excessive mitochondrial ROS generation, NFATc4 activation, and RyR2 mRNA downregulation. …”
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Quantifying uncertainty in anthropogenic causes of injury and mortality for an endangered baleen whale by Daniel W. Linden, Jeffrey A. Hostetler, Richard M. Pace III, Lance P. Garrison, Amy R. Knowlton, Véronique Lesage, Rob Williams, Michael C. Runge

“…Our approach is relevant to other monitored populations where cause‐specific injuries from multiple threats can be observed in live and dead individuals.…”
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The Shiism Dimension in Iran's Relations with Europe: The Example of Germany-France-United Kingdom by Orhan Karaoğlu

“…The concentration of Shiites and organizations in Germany in a single center is entirely in line with Iran's aim of "uniting the Shiites of the world under its rule and spreading Shiism (the belief in velayat-e faqih) from a single center". Approximately 200,000 Shiites live in France. …”
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