Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice by José Belizário, Luiz Vieira-Cordeiro, Sylvia Enns

“…Under stress conditions, cells in living tissue die by apoptosis or necrosis depending on the activation of the key molecules within a dying cell that either transduce cell survival or death signals that actively destroy the sentenced cell. …”
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SenPred: a single-cell RNA sequencing-based machine learning pipeline to classify deeply senescent dermal fibroblast cells for the detection of an in vivo senescent cell burden by Bethany K. Hughes, Andrew Davis, Deborah Milligan, Ryan Wallis, Federica Mossa, Michael P. Philpott, Linda J. Wainwright, David A. Gunn, Cleo L. Bishop

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Medical Assistance in Dying for Persons Suffering Solely from Mental Illness in Canada by Chloe Eunice Panganiban, Srushhti Trivedi

“…Deontology: The Duty to Recognize Vulnerability and Relieve Suffering The argument here begins with the fundamental focus of deontology—that moral duty lies in an action rather than in its consequences. …”
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Laparoscopic Splenectomy to Salvage Renal Transplants from Severe Acute Antibody-Mediated Rejection by Michael Latzko, Sakshi Jasra, Sana Akbar, Harry Sun, Sadanand Palekar

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Decoding HIV-associated neurocognitive disorders: a new perspective from multimodal connectomics by Zhongkai Zhou, Wei Wang, Hui Li, Ying Shi, Lingling Zhao, Yibo Lu, Xingchen Wei, Hongjun Li

“…Currently, HIV-associated neurocognitive disorders (HAND) remains one of the major challenges faced by people living with HIV (PLWH). HAND involves the vulnerability of neural circuits caused by synaptic degeneration and abnormal synaptic pruning. …”
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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal. by William J Cisneros, Shimaa H A Soliman, Miriam Walter, Lacy M Simons, Daphne Cornish, Simone De Fabritiis, Ariel W Halle, Eun-Young Kim, Steven M Wolinsky, Ramon Lorenzo-Redondo, Ali Shilatifard, Judd F Hultquist

“…Finally, we demonstrate that KL-2 enhances viral reactivation in peripheral blood mononuclear cells (PBMCs) from people living with HIV (PLWH) on suppressive ART, most notably in combination with inhibitor of apoptosis protein antagonists (IAPi). …”
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Learning from “Knocks in Life”: Food Insecurity among Low-Income Lone Senior Women by Rebecca J. Green-LaPierre, Patricia L. Williams, N. Theresa Glanville, Deborah Norris, Heather C. Hunter, Cynthia G. Watt

“…Building on earlier quantitative work where we showed that lone senior households reliant on public pensions in Nova Scotia (NS), Canada lacked the necessary funds for a basic nutritious diet, here we present findings from a qualitative study involving in-depth interviews with eight low-income lone senior women living in an urban area of NS. …”
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Potential Technosignature from Anomalously Low Deuterium/Hydrogen in Planetary Water Depleted by Nuclear Fusion Technology by David C. Catling, Joshua Krissansen-Totton, Tyler D. Robinson

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Real-time trajectory imaging of alpha particles emitted from actinium-225 and its daughter radionuclides by Seiichi Yamamoto, Masao Yoshino, Kenji Shirasaki, Kohei Nakanishi, Kei Kamada, Akira Yoshikawa, Jun Kataoka

“…We successfully tracked particle trajectories with varying lengths and intensities for 4 different alpha particles emitted from Ac-225 and its daughter radionuclides with a spatial resolution of 1.0 μm. …”
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Two new species of Plagiostomum (Prolecithophora, Plagiostomidae) from China with its morphology, phylogeny, and reproductive strategy by Leyuan Feng, Shiyan Zhang, Ming Tao, Ting Sun, Antai Wang

“…Here, we describe two new species of Plagiostomum collected from the intertidal zone of the South China Sea, based on the integrative studies of morphology, phylogeny, reproduction, and juvenile development. …”
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DsTau: study of tau neutrino production with 400 GeV protons from the CERN-SPS by The DsTau collaboration, Shigeki Aoki, Akitaka Ariga, Tomoko Ariga, Sergey Dmitrievsky, Elena Firu, Dean Forshaw, Tsutomu Fukuda, Yuri Gornushkin, Ali Murat Guler, Maria Haiduc, Koichi Kodama, Masahiro Komatsu, Muhtesem Akif Korkmaz, Umut Kose, Madalina Miloi, Antonio Miucci, Motoaki Miyanishi, Mitsuhiro Nakamura, Toshiyuki Nakano, Alina Neagu, Hiroki Rokujo, Osamu Sato, Elizaveta Sitnikova, Yosuke Suzuki, Tomoki Takao, Svetlana Vasina, Mykhailo Vladymyrov, Thomas Weston, Junya Yoshida, Masahiro Yoshimoto

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Molecular identification and antibiotic clearance of Mycoplasma arginini and Mycoplasma orale from cell cultures infected with Rickettsia or Ehrlichia species by Michelle E. J. Allerdice, Savannah L. Shooter, Maria F. B. M. Galletti, Joy A. Hecht, Sandor E. Karpathy, Christopher D. Paddock

“…Historically, mycoplasma-contaminated Rickettsia cultures were cleared of contaminants by inoculating laboratory mice and re-isolating mycoplasma-free Rickettsia from brain endothelial cells. However, this method requires the sacrifice of live animals and is not always effective. …”
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From the Other Shore: Exploring Home and Spatial Duality in Leïla Sebbar’s Le silence des rives (Silence on the Shores) by Nassima Amirouche

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First report of Haemaphysalis bispinosa, molecular-geographic relationships of Ixodes granulatus and a new Dermacentor species from Vietnam by Sándor Hornok, Jenő Kontschán, Gergő Keve, Nóra Takács, Dat Van Nguyen, Khanh Ngoc Phuong Ho, Tamás Görföl, Yuanzhi Wang, Róbert Farkas, Thanh Thi Ha Dao

“…However, I. granulatus, the Asian rodent tick, has a mixed geographical pattern of haplotypes, probably because it may associate with either synanthropic or wild-living rodents as primary hosts. This tick species is recorded here, for the first time to our knowledge, as parasitizing lorises in Vietnam and its region. …”
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Application of Fuzzy Hierarchy Analysis method to identify factors on the professional development of newly graduated teachers from Farhangian University by Nader Habibzadeh, Ebrahim Salehiomran, Saeed Ghiyasinoshan

“…Abstract The purpose of this research is to use the fuzzy hierarchy analysis method to identify the effective factors on the professional development of newly graduated teachers from Farhangian University. The research method is applicable in terms of purpose, and descriptive-survey based on the method of data collection. …”
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Environmental Hazard of Polypropylene from Disposable Face Masks Linked to the COVID-19 Pandemic and Its Possible Mitigation Techniques through a Green Approach by Selvakumar Vijayalakshmi, Preethi Gopalsamy, Karnan Muthusamy, Dinesh Kumar Sundarraj, Steffi Pulikondan francis, Thiyagarajan Ramesh, Deog-Hwan Oh, Duong Ly Thi Thuy, Tuyet Thi Anh Truong, Huu Tap Van, Shankar Karuppannan

“…The methods and strain presented here reveal the potential biodegrading agents of PP masks.…”
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Carcinogenesis and Chemotherapy Viewed from the Perspective of Stoichiometric Network Analysis (SNA): What Can the Biological System of the Elements Contribute to an Understanding... by Stefan Franzle, Bernd Markert

“…The SNA-based classifications of autocatalytic networks in cell biology are outlined here to identify new approaches to chemotherapy.…”
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Forest Carbon Storage in the Western United States: Distribution, Drivers, and Trends by Jazlynn Hall, Manette E. Sandor, Brian J. Harvey, Sean A. Parks, Anna T. Trugman, A. Park Williams, Winslow D. Hansen

“…Harvest and private ownership reduced carbon, particularly in the PNW. Since 2005, live carbon declined across much of the western US, likely from drought and fire. …”
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Development of a human tyrosinase activity inhibition assay using human melanoma cell lysate by Gengxuan Shi, Yunjiang Feng, Kathryn F. Tonissen

“…However, these methods are either time consuming and expensive or are not human TYR (hsTYR) specific. Here, we describe a simple hsTYR assay using cell lysate prepared from pigmented human melanoma cell lines that takes less than 3 hours to complete after collecting cell pellets. …”
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Raising public awareness on anthropogenic underwater noise by means of playful activities and serious games by Paolo Diviacco, Massimiliano Iurcev

“…Although great progress has been made both from a normative and scientific point of view, public perception of this hazard is very limited. …”
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