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A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity
Published 2025-01-01“…Abstract Background Agonistic monoclonal antibodies targeting 4-1BB/CD137 have shown preclinical promise, but their clinical development has been limited by severe liver toxicity or limited efficacy. …”
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Changing approaches to interactive marketing communications due to the development of 5G technology
Published 2022-01-01“…The process of changing approaches to interactive marketing communications, due to the development of 5G technology – high-speed data transmission over 5G wireless networks has been reviewed. The main facts about 5G technology have been given, the impact of its introduction on consumer behavior, the penetration of augmented and virtual reality technologies into everyday life and the change in the format of marketing communications in the following areas have been considered: retail and delivery of goods, virtual spaces for work and business, mobile cloud gaming and streaming, art, street traffic and parking, public transport, pedestrian and bicycle traffic, weather conditions and energy supply.The key directions of development of interactive marketing communications with the arrival of 5G have been considered: delivery of messages to any place and at any time, an increase in the number of connected devices, instant feedback, new formats and media.Conclusions have been drawn regarding the changes in interactive marketing communications: due to the ultra-high speeds of 5G, the loading time of the commercial will be significantly reduced, which will significantly improve the consumer experience at the level of using devices and applications. …”
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264
Association of calf circumference with osteoporosis and hip fracture in middle-aged and older adults: a secondary analysis
Published 2024-12-01“…Calf circumference (CC) has been used as a simple and practical skeletal muscle marker to diagnose sarcopenia. …”
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Designing a model for the development of questioning skills based on the school context in primary school students
Published 2024-09-01“…The research method of data-based theory and qualitative approach has been used to answer this question in the qualitative part. 2020 MaxQDA software was used for data analysis. …”
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268
RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study
Published 2025-02-01“…Study registration: This study has been registered on clinicaltrials.gov (NCT05603819). …”
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269
Overlooked discrepancies in protocols undermine coastal restoration practices in China
Published 2025-01-01Get full text
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270
ECONOMIC AND FINANCIAL SITUATION OF HOUSEHOLDS IN POLAND – ANALYSIS AND DIAGNOSIS
Published 2017-12-01Get full text
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271
Migrant settlement distribution in urban centers of megacities Jakarta
Published 2024-01-01“…Rapid movement of people and goods has been a remarkable distinction of Jakarta. …”
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272
Alloy Substitution in a Critical Raw Materials Perspective
Published 2020-01-01“…Such raw materials, classified as critical, form a strong industrial base, producing a lot of goods and applications used in everyday life and modern technologies. …”
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273
Designing a multi-period multi-stage supply chain network under uncertainty
Published 2024-06-01“…The supply chain of perishable goods, including food, dairy products, medicines, and blood products, has recently received attention due to their impact on human life. …”
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Presenting the local model of increasing the market share in Iran's dairy industry with a qualitative approach
Published 2024-08-01“…The growing population, the diversification of consumer tastes, the increasing importance of the health of food products, healthy nutrition as a factor in preventing the occurrence of many diseases, the prominence of the role of food from the economic, health, etc. aspects all show the significant role of nutrition and food industry in today human life (Khakbeez, Rezaei & Azizi, 2021). Milk and its products are of special importance in human life due to their extraordinary nutritional value, and they always provide part of the body's needs in the human food pyramid, including protein and some vitamins and especially calcium, but they do not have substitute products; therefore, in terms of examining alternative goods, the circle of investigation should be limited to all types of dairy products (Mousavinejad & Khoramnia, 2021). …”
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A relação campo-cidade sob a ótica da transformação de um bairro rural em distrito municipal : o caso de Moçambo, no município de Muzambinho-MG, Brasil
Published 2021-06-01“…The relations between the countryside and the city have always been marked by complexities and particularities that can be evidenced when studying a municipal district, once considered the interface of this relationship, based on academic theories. …”
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276
Investigating the consequences of urban creep in Shahrekord
Published 2020-03-01“…The most important environmental-physical consequences are increased environmental pollution, destruction of traditional architecture, destruction of biodiversity; major economic consequences of stock markets and rising land and housing prices, diminishing villagers' reluctance to productive activities (agriculture and livestock), capital flight from villages And their savings in the city and the rising cost of living amidst the socio-cultural consequences of luxury and the tendency to consume luxury goods, reduce solidarity and participation, crowding and crowding in cities, modeling of life and urbanization culture. have been.…”
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Characteristics of the transportation structure of the transport-logistical complex and its dynamics
Published 2020-01-01“…The structure of the cargo transportation throughout the transport and forwarding complex of Russia is quite heterogeneous. The fact has been highlighted, that in the structure of transported goods a trend of growth in the volume of transportation of low-income goods against the background of a stable level of transportation volumes of high-yield cargo is observed. …”
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Bulky Vehicles Recycling. Part 2 - Recycling of Selected Vehicle Components
Published 2020-12-01“…Recycling of end-of-life passenger vehicles is a well-known topic, and there are many literary reports in this regard. …”
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280
The Transformation of Commons in Roşia-Montană. Which Property Regimen for Which Development?
Published 2023-05-01“…The community of this village structured around some common goods owing to the harsh environment of mountain living conditions, as well as to the risks inherent to the mining activity. …”
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