AI-Based Advanced Approaches and Dry Eye Disease Detection Based on Multi-Source Evidence: Cases, Applications, Issues, and Future Directions by Mini Han Wang, Lumin Xing, Yi Pan, Feng Gu, Junbin Fang, Xiangrong Yu, Chi Pui Pang, Kelvin Kam-Lung Chong, Carol Yim-Lui Cheung, Xulin Liao, Xiaoxiao Fang, Jie Yang, Ruoyu Zhou, Xiaoshu Zhou, Fengling Wang, Wenjian Liu

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TROPION-Breast04: a randomized phase III study of neoadjuvant datopotamab deruxtecan (Dato-DXd) plus durvalumab followed by adjuvant durvalumab versus standard of care in patients... by Heather L. McArthur, Sara M. Tolaney, Rebecca Dent, Peter Schmid, Jamil Asselah, Qiang Liu, Jane Lowe Meisel, Naoki Niikura, Yeon Hee Park, Gustavo Werutsky, Giampaolo Bianchini, Jay C. Andersen, Robert Kozarski, Nana Rokutanda, Barbara Pistilli, Sibylle Loibl

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RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

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Correction: Artificial intelligence for quantifying immune infiltrates interacting with stroma in colorectal cancer by Jing Yang, Huifen Ye, Xinjuan Fan, Yajun Li, Xiaomei Wu, Minning Zhao, Qingru Hu, Yunrui Ye, Lin Wu, Zhenhui Li, Xueli Zhang, Changhong Liang, Yingyi Wang, Yao Xu, Qian Li, Su Yao, Dingyun You, Ke Zhao, Zaiyi Liu

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Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old by Yingsi Zeng, Zijun Chen, Qinkai Chen, Xiaojiang Zhan, Haibo Long, Fenfen Peng, Fengping Zhang, Xiaoran Feng, Qian Zhou, Lingling Liu, Xuan Peng, Evergreen Tree Nephrology Association, Guanhua Guo, Yujing Zhang, Zebin Wang, Yueqiang Wen, Jiao Li, Jianbo Liang

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Retrospective analysis of disease characteristics and treatment patterns among patients with esophageal cancer across 14 surgically represented centers by Zhihao Lu, Mingfei Geng, Yongtao Han, Jianzhong Cao, Jun Wang, Tianshu Liu, Xianglin Yuan, Xue Meng, Yanqiao Zhang, Rong Zhao, Lixin Wan, Enxiao Li, Wenran Wang, Zhijie Li, Danfeng Shi, Jing Qian, Si Shi, Fengshi Dong, Lin Shen

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Developing a master of science in health research ethics program in Northern Nigeria: a needs assessment by Caitlin Bieniek, Fatimah I. Tsiga-Ahmed, Aishatu L. Adamu, Usman J. Wudil, C. William Wester, Zubairu Iliyasu, Muktar H. Aliyu, Elisa J. Gordon, Elizabeth S. Rose

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Effect of Food on the Steady-State Pharmacokinetics of Tenofovir and Emtricitabine plus Efavirenz in Ugandan Adults by Mohammed Lamorde, Pauline Byakika-Kibwika, William S. Tamale, Francis Kiweewa, Mairin Ryan, Alieu Amara, John Tjia, David Back, Saye Khoo, Marta Boffito, Cissy Kityo, Concepta Merry

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T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint pr... by Stephanie Schlichtner, Inna M Yasinska, Gurprit S Lall, Steffen M Berger, Sabrina Ruggiero, Dietmar Cholewa, Nijas Aliu, Bernhard F Gibbs, Elizaveta Fasler-Kan, Vadim V Sumbayev

“…Our aims were to elucidate whether T cells can induce galectin-9 secretion in human cancer cells derived from solid malignant tumors and whether this soluble form displays higher systemic immunosuppressive activity compared with the cell surface-based protein.Methods A wide range of human cancer cell lines derived from solid tumours, keratinocytes and primary embryonic cells were employed, together with helper and cytotoxic T cell lines and human as well as mouse primary T cells. …”
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Nonacademic predictors of China medical licensing examination by Jie Sun, Yingying Xie, Ningnannan Zhang, Jingliang Cheng, Meiyun Wang, Bing Zhang, Wenzhen Zhu, Hui Zhang, Shijun Qiu, Xiaojun Xu, Yongqiang Yu, Tong Han, Zuojun Geng, Weihua Liao, Bo Gao, Wen Qin, Feng Liu, Meng Liang, Qiang Xu, Jilian Fu, Jiayuan Xu, Mengge Liu, Peng Zhang, Wei Li, Dapeng Shi, Caihong Wang, Xi-Nian Zuo, Quan Zhang, Feng Chen, Jiance Li, Zhihan Yan, Wen Shen, Yanwei Miao, Junfang Xian, Longjiang Zhang, Kai Xu, Zhaoxiang Ye, Jing Zhang, Guangbin Cui, Chunshui Yu, for the CHIMGEN Consortium

“…Methods In 1202 medical students, we conducted the deletion-substitution-addition (DSA) and structural equation model (SEM) analyses to identify nonacademic predictors of GMKT performance from 98 candidate variables including early life events, physical conditions, psychological and personality assessments, cognitive abilities, and socioeconomic conditions. …”
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Monitoring of Circulating Tumor DNA and Indication of De-Escalation Adjuvant Targeted Therapy for EGFR-Mutated NSCLC After Complete Resection by Song Dong, PhD, Bingfa Yan, PhD, Si-Yang Liu, PhD, Xuan Gao, PhD, Hui-Zhao Hong, MD, Hong-Ji Li, MD, Wei Gao, PhD, Hong-Hong Yan, PhD, Si-Yang Maggie Liu, PhD, Hai-Yan Tu, PhD, Yi Pan, PhD, Qing Zhou, PhD, Xue-Ning Yang, PhD, Xue-Feng Xia, PhD, Xin Yi, PhD, Wen-Zhao Zhong, PhD, Yi-Long Wu, MD, Jia-Tao Zhang, PhD

“…Introduction: EGFR tyrosine kinase inhibitor (TKI) is the standard adjuvant treatment for patients with stages IB to IIIA EGFR-mutated NSCLC. Nevertheless, adapting this approach to include a molecular residual disease (MRD)-guided de-escalation strategy warrants further investigation. …”
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Field Observations During the Tenth Microwave Water and Energy Balance Experiment (MicroWEX-10): from March 1, 2011 through January 5, 2012 by Tara Bongiovanni, Pang-Wei Liu, Karthik Nagarajan, Daniel Preston, Patrick Rush, Xueyang Duan, Guanbo Chen, Robert Terwilleger, Alejandro Monsivais-Huertero, Roger De Roo, Jasmeet Judge, Ruzbeh Akbar, Mary Morris, Olivia Williams, Lindsey Marks, Courtnay Cardozo, Mahta Moghaddam, Anthony England

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Apoptotic PET Imaging of Rat Pulmonary Fibrosis With [F]ML-8 by Ying Xiong MM, Dahong Nie BM, Shaoyu Liu PhD, Hui Ma BM, Shu Su BM, Aixia Sun PhD, Jing Zhao MD, PhD, Zhanwen Zhang PhD, Xianhong Xiang MD, PhD, Ganghua Tang MD, PhD

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Species evolution: cryptic species and phenotypic noise with a particular focus on fungal systematics by Anusha H. Ekanayaka, Anusha H. Ekanayaka, Samantha C. Karunarathna, Samantha C. Karunarathna, Saowaluck Tibpromma, Arun Kumar Dutta, Danushka Sandaruwan Tennakoon, Anuruddha Karunarathna, Ekachai Chukeatirote, Dong-Qin Dai, Steven L. Stephenson, Sajeewa S. N. Maharachchikumbura, Chao Liu, Alan J. L. Phillips

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Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: a systematic review and network meta-analysis by Andrea Cipriani, Pim Cuijpers, Yuqing Zhang, David Cohen, Jürgen Barth, Peng Xie, Cinzia Del Giovane, Xinyu Zhou, Donna Gillies, Teng Teng, Xuemei Li, Li Fan, Yajie Xiang, John R. Weisz, Xueer Liu, Yuanliang Jiang, Kang Du, Arun V. Ravindran

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Exploring symptom clusters in Chinese patients with peritoneal dialysis: a network analysis by Di-fei Duan, Xue-li Zhou, Yu Yan, Yuan-mei Li, Yan-hua Hu, Qin Li, Xiang Peng, Qin Gu, Xiao-ying Li, Hui Feng, Ai-jiao Tang, Pan Liu, Hui-hui Xu, Ruo-xi Liao, Deng-yan Ma

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Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis by Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi

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Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models by Ling Xiong, Dustin Beyer, Na Liu, Tina Lehmann, Sophie Neugebauer, Sascha Schaeuble, Oliver Sommerfeld, Philipp Ernst, Carl-Magnus Svensson, Sandor Nietzsche, Sebastian Scholl, Tony Bruns, Nikolaus Gaßler, Markus H. Gräler, Marc Thilo Figge, Gianni Panagiotou, Michael Bauer, Adrian T. Press

“…Sepsis is a life-threatening organ failure resulting from a poorly regulated infection response. …”
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Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

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Effects of moderate bandwidth on laser absorption and stimulated Raman sidescattering by Ning Kang, Yao Zhao, Anle Lei, Huiya Liu, Fujian Li, Guoxiao Xu, Honghai An, Jun Xiong, Ruirong Wang, Zhiyong Xie, Zhiheng Fang, Wei Wang, Lailin Ji, Shenlei Zhou, Guangyue Hu, Jiwei Li, Lifeng Wang, Yanqi Gao, Xiuguang Huang, Sizu Fu

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