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14541
Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences
Published 2017-01-01“…These results suggest an evolutionary link between Vpr and gp120 in HIV-1-infected patients.…”
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14542
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14543
Seaweed (Porphyra) cultivation enhances production of autochthonous refractory dissolved organic matter in coastal ecosystems
Published 2025-02-01“…Redundancy analysis revealed that more microbial modules mediated organic matter transformations during the cultivation period, leading to a 169% higher estuarine addition of microbially-sourced humic-like C3 compared to the non-cultivation period. Our findings demonstrate that Porphyra cultivation enhanced coastal carbon sequestration by promoting the autochthonous production and transformation of refractory DOM, which has important implications for the sustainable management and development of coastal blue carbon strategies.…”
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14545
Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates
Published 2025-03-01“…At 1 month post-dose, we compared tissue vector genomes, mRNA, and microdystrophin-FLAG protein levels by meso-scale discovery-enzyme-linked immunosorbent assay, liquid chromatography-mass spectrometry, and immunofluorescence. …”
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14546
Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK
Published 2025-02-01“…Monetary values were applied to the results.The BNZP policy compared with BAU gave 4.9 (95 % confidence interval 1.0–9.0) million life-years gained (LYG) (UK population, to 2154), including 1.1 (0.7–1.6) million LYG from active travel improvements. …”
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14547
α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia
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14548
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling
Published 2025-01-01“…Alternatively, 15-oxo-LXA4, an electrophilic α,β-unsaturated ketone, alkylates nucleophilic amino acids and can modulate redox-sensitive transcriptional regulatory protein and enzyme function. 15-oxo-LXA4 activated nuclear factor (erythroid related factor 2)-like 2-regulated expression of anti-inflammatory and repair genes and inhibited NF-κB-regulated pro-inflammatory mediator expression. …”
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14549
Activation of three targets by a TAL effector confers susceptibility to bacterial blight of cotton
Published 2025-01-01“…Abstract Bacterial transcription activator-like effectors (TALEs) promote pathogenicity by activating host susceptibility (S) genes. …”
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14550
Cross‐ethnicity face anti‐spoofing recognition challenge: A review
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14552
Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb
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14556
The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial
Published 2025-01-01“…eLife…”
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14557
The southward shift of hurricane genesis over the northern Atlantic Ocean
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14558
Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study
Published 2024-12-01“…Abstract Background Epigenetic modifications are crucial in tumourigenesis, yet the changes in novel epigenetic regulators like 5‐hydroxymethylcytosines (5hmC) during the evolution of gastric premalignant lesions remain poorly understood. …”
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14559
Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development
Published 2025-01-01“…Here, we present two cases of male infertility linked to novel TDRD6 variants, associated with oligoasthenoteratozoospermia (OAT) and early embryonic arrest. …”
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14560
Integrating genetics and transcriptomics to characterize shared mechanisms in digestive diseases and psychiatric disorders
Published 2025-01-01“…MTAG identify 60 novel pleiotropic loci for IBS and 14 for GERD, predominantly located near genes associated with neurological pathways. …”
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