Succinate supplementation alleviates liver cancer by inhibiting the FN1/SQLE axis-mediated cholesterol biosynthesis by Shuyuan Chang, Ayaka Tomii, Yunfei Zhou, Xun Yang, Yihong Dong, Jun Yan, Aodi Wu, Yumeng Wang, Qingxin Zhang, Hongxue Meng, Lei Yu, Wei Sun, Dabin Liu

Get full text

Model Evaluation and Uncertainty Analysis of PM2.5 Components over Pearl River Delta Region Using Monte Carlo Simulations by Qian Wu, Xiao Tang, Lei Kong, Zirui Liu, Duohong Chen, Miaomiao Lu, Huangjian Wu, Jin Shen, Lin Wu, Xiaole Pan, Jie Li, Jiang Zhu, Zifa Wang

Get full text

Exosome-loaded tannic acid–thioctic acid hydrogel enhances wound healing in coagulation disorders by Yuesheng Tu, Weixin Zheng, Zichu Ding, Jie Xiang, Qinfeng Yang, Yuchen Liu, Jue Cao, Yuling Shen, Zinan Tang, Shen Lin, Lei Fan, Yaowen Xu, Bin Chen

Get full text

Hexagonal zinc oxide nanoparticles: a novel approach to combat multidrug-resistant Enterococcus faecalis biofilms in feline urinary tract infections by Alaa H. Sewid, Alaa H. Sewid, Mohamed Sharaf, Mohamed Sharaf, Azza S. El-Demerdash, Sherif M. Ragab, Fatimah O. Al-Otibi, Mohamed Taha Yassin, Chen-Guang Liu

Get full text

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

Get full text

Association between the low-density lipoprotein to high-density lipoprotein ratio and prognosis in critically ill intracerebral hemorrhage patients: a retrospective cohort study fr... by Yuchen Liu, Houxin Fu, Yue Wang, Yi Zhong, Rongting Zhang, Jingxuan Sun, Tianquan Yang, Yong Han, Yongjun Xiang, Bin Yuan, Ruxuan Zhou, Min Chen, Hangzhou Wang

“…Initially, the association between LHR and short-term outcomes in ICH patients, including ICU mortality, in-hospital mortality, and 28-day mortality, was analyzed using Cox regression in both continuous and categorical models. …”
Get full text

Correction: Relationship between changes in the triglyceride glucose-body mass index and frail development trajectory and incidence in middle-aged and elderly individuals: a nation... by Kai Guo, Qi Wang, Lin Zhang, Rui Qiao, Yujia Huo, Lipeng Jing, Xiaowan Wang, Zixuan Song, Siyu Li, Jinming Zhang, Yanfang Yang, Jinli Mahe, Zhengran Liu

Get full text

Impact of social determinants and medical mistrust on parent-child HPV vaccination in economically disadvantaged communities: implications for cancer prevention by Marcelo M. Sleiman, Mary Rose Yockel, Mingqian Liu, Joanne Wendolowski, Lucile L. Adams-Campbell, Chiranjeev Dash, Lisa Carter-Bawa, Abraham Aragones, Sahana Arumani, Kenneth P. Tercyak

“…For parents with <=HS education, when levels of provider trust were strong, they were more open to vaccinating their children.ConclusionsHPV vaccine prevalence was low among parents and children living in disadvantaged communities. Comprehensive education and intervention to build trust are warranted to prevent the spread of HPV-linked cancers and reduce cancer disparities.…”
Get full text

Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

“…Cinobufagin effectively induced PANoptosis, leading to increased immunogenic cell death, facilitated tumor-associated microglia/macrophages (TAMs) polarization towards an M1-like phenotype while augmenting CD4+/CD8 + T cell infiltration and activation. …”
Get full text

Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

Get full text

A Pooling Genome-Wide Association Study Identifies Susceptibility Loci and Signaling Pathways of Immune Thrombocytopenia in Chinese Han Population by Yanmei Xu, Jing Li, Wentao Yang, Xiaoli Tang, Bo Huang, Jing Liu, Jin Lin, Jing Zhang, Weiming Yang, Shuqi Li, Fan Sun, Libin Deng, Xiaozhong Wang

Get full text

The effect of baseline versus early glucocorticoid use on immune checkpoint inhibitor efficacy in patients with advanced NSCLC by Yifan Wang, Yifan Wang, Jianying Zhou, Simin Peng, Simin Peng, Zhao Cui, Zhao Cui, Weiqi Wang, Weiqi Wang, Wenqin Zeng, Wenqin Zeng, Tingting Qiu, Zhentian Liu

Get full text

Reduced γ-Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk by Junjie Wang, Yingying Tang, Tianhong Zhang, Huiru Cui, Lihua Xu, Botao Zeng, Yu Li, Gaiying Li, Chunbo Li, Hui Liu, Zheng Lu, Jianye Zhang, Jijun Wang

Get full text

Tunable control of Cas12 activity promotes universal and fast one-pot nucleic acid detection by Zhou-Hua Cheng, Xi-Yan Luo, Sheng-Song Yu, Di Min, Shu-Xia Zhang, Xiao-Fan Li, Jie-Jie Chen, Dong-Feng Liu, Han-Qing Yu

“…Additionally, this universal assay accommodates both classic and suboptimal PAMs, as well as various Cas12a subtypes such as LbCas12a, AsCas12a, and AapCas12b. Such a robust method demonstrates sensitivity and specificity exceeding 95% in the detection of monkeypox pseudovirus, influenza A virus, and SARS-CoV-2 from saliva or wastewater samples, when compared with qPCR or RT-qPCR. …”
Get full text

The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient... by Chen-Yan Min, Yue Gao, Yuan Li, Yi-Ning Jiang, Ying-Kun Guo, Hua-Yan Xu, Rong Xu, Xi Liu, Li-Ting Shen, Zhi-Gang Yang

“…Background Ischemia with nonobstructive coronary arteries (INOCA) has high morbidity, mortality, and poor quality of life. Metabolic syndrome (MetS) is a complex of multiple cardiac metabolic risk factors, significantly increasing the risk of major adverse cardiovascular events in INOCA patients. …”
Get full text

Efficacy and Safety of CART Cell Therapy in Aggressive B‐Cell Lymphomas Involving the Gastrointestinal Tract by Lixia Ma, Yimeng Dou, Rui Liu, Teng Xu, Fan Yang, Peihao Zheng, Shaomei Feng, Yuelu Guo, Hui Shi, Fei Xue, Biping Deng, Xiaoyan Ke, Kai Hu

“…The disease status of patients who failed multiple lines of therapy was progressive disease (PD). Before CART cell infusion, patients received an FC regimen (fludarabine and cyclophosphamide) lymphodepletion. …”
Get full text

Cross-cultural insights into internet addiction and mental health: a network analysis from China and Malawi by Mengze Li, Yidi Wang, Bin Liu, Xiaoli Ni, Zhujing Ma, Fengzhan Li, Tifei Yuan, Hongyi Chen, Zhongying Wu, Qiannan Jia, Lei Song, Yinchuan Jin, Qun Yang

Get full text

Oral probiotic extracellular vesicle therapy mitigates Influenza A Virus infection via blunting IL-17 signaling by Hongxia Zhou, Wenbo Huang, Jieting Li, Peier Chen, Lihan Shen, Wenjing Huang, Kailin Mai, Heyan Zou, Xueqin Shi, Yunceng Weng, Yuhua Liu, Zifeng Yang, Caiwen Ou

Get full text

Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders by Guangming Zhang, Huayuan Wei, Anliu Zhao, Xu Yan, Xiaolu Zhang, Jiali Gan, Maojuan Guo, Jie Wang, Fayan Zhang, Yifang Jiang, Xinxing Liu, Zhen Yang, Xijuan Jiang

Get full text

Prevalence and predictors of short stature in children aged 3–18 years in Hainan Province, China: a cross-sectional study by Mi Yan, Mi Yan, Yingying Qin, Yingying Qin, Hongai Li, Chuican Huang, Haidan Li, Li Liu, Yuhua Cai, Lichun Fan, Wei Xiang, Xiaoyan Huang, Xiaoyan Huang

Get full text