RNF128 deficiency in macrophages promotes colonic inflammation by suppressing the autophagic degradation of S100A8 by Xianwen Ran, Yue Li, Yahui Ren, Weilong Chang, Rui Deng, Huifen Wang, Weiwei Zhu, Yize Zhang, Yudie Cai, Jia Hu, Di Wang, Zhibo Liu

“…Abstract Macrophages play important roles in maintaining intestinal homeostasis and in the pathogenesis of inflammatory bowel diseases (IBDs). However, the underlying mechanisms that govern macrophage-mediated inflammation are still largely unknown. …”
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Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence by Liu B, Bao Z, Chen W, Xi X, Ge X, Zhou J, Zheng X, Zhang P, Deng W, Ding R, Zhou M, Fang J

“…Bing Liu,1– 3,* Zhiyao Bao,1– 3,* Wei Chen,1– 3,* Xiaotong Xi,4,5,* Xiao Ge,1– 3 Jun Zhou,1– 3 Xiaoyan Zheng,6 Peipei Zhang,4,5 Wanglong Deng,4,5 Ran Ding,4,5 Min Zhou,1– 3 Jie Fang7 1Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Institute of Respiratory Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 3Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Diseases, Shanghai, 200025, People’s Republic of China; 4State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 5Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing, 210018, People’s Republic of China; 6Department of Pulmonary and Critical Care Medicine, Zhoushan Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Zhoushan, 316000, People’s Republic of China; 7Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Fang, Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email fj40517@rjh.com.cn Min Zhou, Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email doctor_zhou_99@163.comBackground: Targeted next-generation sequencing (tNGS) is a high-throughput and cost-effective diagnostic alternative for pneumonia, with the ability to simultaneously detect pathogens, antimicrobial resistance genes, and virulence genes. …”
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Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis by Litong Ran, Xiufei Liu, Yongfeng Tian, Jiaran Zhu, Zhengyuan Gong, Qiao Qiao, Xin Jiang, Yuren Wang, Guojun Yang, Hongting Zheng, Yi Zheng, Hua Qu

“…Gene ontology and KEGG enrichment analyses identified that these proteins were enriched in processes involving infection, inflammatory response and cell adhesion and junction, which likely contribute to the pathogenesis. Moreover, the top three high-abundance proteins (nicotinamide N-methyltransferase (NNMT), FTL and thymidine phosphorylase (TYMP)) were further validated in the plasma from a larger SAT cohort using an enzyme-linked immunosorbent assay. …”
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Dexmedetomidine Attenuates Inflammation in Elderly Patients Following Major Hepatobiliary and Pancreatic Surgery: A Randomized Clinical Trial [Corrigendum] by Chen X, Chen Q, Qin Z, Alam A, Zhao H, West R, Liu X, Li J, Li X, Yi B, Ma D, Gu J

“…The bounds of the box show the interquartile range, and the centre line of the box shows the median. Vertical endpoints represent the 5th and 95th percentiles. …”
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The prognostic value of the 8th American Joint Committee on cancer anatomic and prognostic stage groups for penile cancer: A multicenter collaboration study by Xueying Li, Yepeng Guo, Antonio Augusto Ornellas, Jiun-Hung Geng, Yonghong Li, Wayne Lam, Yabing Cao, Zhuowei Liu, Hui Han, Fangjian Zhou, Zaishang Li

“…Results: According to the 8th AJCC anatomic and prognostic stage groups, the 5-year DSS rates for patients with stages 0is/a, I, IIA, IIB, IIIA, IIIB, and IV disease were 100%, 99%, 86%, 81%, 66%, 34%, and 23%, respectively (p0is/a–I=0.8, pI–IIA<0.001, pIIA–IIB=0.5, pIIB–IIIA<0.001, pIIIA–IIIB<0.001, pIIIB–IV=0.004, and pTotal<0.001). …”
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Characterizing a complex buildup in the Pearl River Mouth Basin of the northern South China Sea: an interplay of carbonates and igneous rocks by Beichen Chen, Leyi Xu, Baojun Liu, Lili Zhang, Dong Xiao, Ya Gao, Ya Gao, Feng Wu, Xueqi Yang, Yaming Zou, Yongkun Ma, Yinglin Zhang

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Animal Models for Human-Pathogenic Coronavirus and Animal Coronavirus Research by Fenglian Xiao, Jincheng Hu, Minsheng Xu, Di Wang, Xiaoyan Shen, Hua Zhang, Jie Miao, Haodong Cai, Jihui Wang, Yaqing Liu, Shan Xiao, Longchao Zhu

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Abnormal dynamic functional networks during pain-free periods: Resting-state co-activation pattern analysis in primary dysmenorrhea by Huiping Liu, Xing Su, Meiling Shang, Ling Ma, Weixian Bai, Hui Wang, Lu Quan, Youjun Li, Zigang Huang, Jiaxi He, Wanghuan Dun, Yuchen Zhang

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Physicochemical, Rheological, Structural, Antioxidant, and Antimicrobial Properties of Polysaccharides Extracted from Tamarind Seeds by Likun Ren, Yang Yang, Xin Bian, Xiaomei Li, Bing Wang, Dangfeng Wang, Dan Su, Linlin Liu, Dehui Yu, Xiaoxue Guo, Xiumin Zhang, Na Zhang

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Continuous Loss of Global Lake Ice Across Two Centuries Revealed by Satellite Observations and Numerical Modeling by Xinchi Wang, Lian Feng, Wei Qi, Xiaobin Cai, Yi Zheng, Luke Gibson, Jing Tang, Xiao‐peng Song, Junguo Liu, Chunmiao Zheng, Brett A. Bryan

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Electroacupuncture Improves Cognitive Function in Senescence-Accelerated P8 (SAMP8) Mice via the NLRP3/Caspase-1 Pathway by Zhitao Hou, Ruijin Qiu, Qingshuang Wei, Yitian Liu, Meng Wang, Tingting Mei, Yue Zhang, Liying Song, Xianming Shao, Hongcai Shang, Jing Chen, Zhongren Sun

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Advance in identified targets of berberine by Penghai Sun, Ziyuan Wang, Yinchao Ma, Yuan Liu, Yintong Xue, Yan Li, Xiang Gao, Yuedan Wang, Ming Chu, Ming Chu, Ming Chu, Ming Chu

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Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period by Mengmeng Xu, Le Liu, Zongze Fan, Lizhu Niu, Wenxi Ning, He Cheng, Mengyun Li, Wenying Huo, Pan Zhou, Hongyu Deng, Wen Chen, Long Che

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Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers by Binhao Liu, Jiacheng Shen, Jiayu Li, Bowen Tian, Bowen Tian, Bin Zhou, Jiachen Gui, Zhimin Li, Yue Zhang, Wenzhi Hu, Qiang Li, Qiang Li

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The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion by Ping Wang, Min Cong, Tianhui Liu, Aiting Yang, Guangyong Sun, Dong Zhang, Jian Huang, Shujie Sun, Jia Mao, Hong Ma, Jidong Jia, Hong You

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High-Flow Nasal Oxygen versus Noninvasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Randomized Controlled Trials by Yanping Du, Huaping Zhang, Zhiyi Ma, Jun Liu, Zhiyong Wang, Meixia Lin, Fayu Ni, Xi Li, Hui Tan, Shifan Tan, Yanling Chai, Xiangzhu Zhong

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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

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Parthenolide Is Neuroprotective in Rat Experimental Stroke Model: Downregulating NF-κB, Phospho-p38MAPK, and Caspase-1 and Ameliorating BBB Permeability by Lipeng Dong, Huimin Qiao, Xiangjian Zhang, Xiaolin Zhang, Chaohui Wang, Lina Wang, Lili Cui, Jingru Zhao, Yinxue Xing, Yanhua Li, Zongjie Liu, Chunhua Zhu

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Mast cells: key players in digestive system tumors and their interactions with immune cells by Feihong Shu, Jie Yu, Youjia Liu, Fang Wang, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xie

“…Specifically, mast cells not only secrete mediators related to pro-tumor function such as trypsin-like enzymes, chymotrypsin, vascular endothelial cell growth factor and histamine, but also mediators related to anti-tumor progression such as cystatin C and IL-17F. …”
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Global burden and cross-country inequalities of nutritional deficiencies in adults aged 65 years and older, 1990–2021: population-based study using the GBD 2021 by Shuang Liang, Shao-Zhi Xi, Jia-Yi Liu, Gui-Chun Tang, Wei-Guang Zhang, Xin-Ru Guo, Chen Yang, Chun Zhang, Guang-Yan Cai

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