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Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment
Published 2025-01-01“…Guangjie Li,1,2,* Fei He,2,* Jianbao Feng,3 Ge Xu,1 Chengye Wu,1 Yufei Qiao,1 Yang Liu,3 Hanlin Chen,1 Pengcheng Du,4 Jizeng Wang2 1The First Hospital of Lanzhou University, Lanzhou, Gansu Province, People’s Republic of China; 2College of Civil Engineering and Mechanics, Lanzhou University, Lanzhou, Gansu Province, People’s Republic of China; 3Hospital of Stomatology, Lanzhou University, Lanzhou, Gansu Province, People’s Republic of China; 4College of Chemistry and Chemical Engineering, Lanzhou University, Gansu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jizeng Wang, Email jzwang@lzu.edu.cnBackground: Osteoarthritis (OA), a prevalent joint disease, causes immense suffering to thousands of patients, impairing their mobility and diminishing their quality of life. …”
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Development and validation of a prognostic and drug sensitivity model for gastric cancer utilizing telomere-related genes
Published 2025-02-01“…Elevated telomerase activity has been linked to the rapid growth and invasiveness of GC tumors. …”
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Proteomics and metabolomics analyses of mechanism underlying bovine sperm cryoinjury
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5-Methoxytryptophan Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Intestinal Epithelial Damage and Inflammatory Response
Published 2024-01-01“…Colitis is a refractory intestinal inflammatory disease significantly affecting the quality of a patient’s life and increasing the risk of exacerbation. The primary factors leading to colitis encompass infections, insufficient blood flow, and the buildup of collagen as well as white blood cells. …”
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Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity
Published 2025-01-01“…To elucidate the toxicity of Sb and its mechanism of action, this study aimed to investigate the adverse effects of Sb on a cosmopolitan insect, housefly (Musca domestica), under a whole life cycle (from embryonic to adult stage) exposure through the examination of a suite of parameters, including biological, physiological, behavioral, and molecular endpoints. …”
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Iron deposition is associated with motor and non-motor network breakdown in parkinsonism
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Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae
Published 2025-01-01“…With the widespread application of pesticides, water pollution problems are becoming more and more serious, which is very likely to cause harm to fish. Lower vertebrates, including fish, have the ability to repair damaged tissues. …”
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CIRBP Regulates Pancreatic Cancer Cell Ferroptosis and Growth by Directly Binding to p53
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Engineering triple O-Ti-O vacancy associates for efficient water-activation catalysis
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Overexpression of SFPQ Improves Cognition and Memory in AD Mice
Published 2025-01-01“…Additionally, synaptic and memory-associated proteins, as well as antioxidant proteins like glutathione S-transferase (GST) and heme oxygenase-1 (HO-1), were upregulated. …”
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Single‐cell landscape of the intrahepatic ecosystem in alcohol‐related liver disease
Published 2025-01-01“…In addition, our results also uncovered the important alterations of nonparenchymal cells, especially macrophages and T/NK populations that responsible for active inflammation responses in alcohol‐related hepatitis and immunosuppressive microenvironment in advanced cirrhosis livers, which likely facilitated the malignant progression of ALD. …”
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Nomogram to predict 3 month prognosis of acute ischemic stroke among young adults
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