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The Dynamic Interplay between the Gut Microbiota and Autoimmune Diseases
Published 2019-01-01“…Here, we present evidence linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing autoimmune diseases.…”
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MSTD: A Multi-Scale Transformer-Based Method to Diagnose Benign and Malignant Lung Nodules
Published 2025-01-01Get full text
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Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK–IDH2 pathway
Published 2023-04-01“…We further showed this in primary hepatocytes, the L02 cell line, and the Caenorhabditis elegans strain. Mechanistically, RTN3 regulated these events through its interactions with glucose‐regulated protein 78 (GRP78), which further inhibited the adenosine 5 monophosphate‐activated protein kinase (AMPK)–isocitrate dehydrogenase 2 (IDH2) pathway. …”
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Erratum to “Therapy of Prostate Cancer by Nanoyam Polysaccharide”
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Gut microbial 3α‐hydroxysteroid dehydrogenase promotes depression in males via degrading testosterone
Published 2025-01-01“…Escherichia coli heterologously expressing 3α‐HSD obtained the capacity to degrade testosterone, causing depression‐like behaviors after gavage to mice. Testosterone supplementation improves depression‐like behavior in mice induced by gavage of Escherichia coli heterologously expressing 3α‐HSD. …”
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Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical f...
Published 2025-01-01“…Compared to LIPE, high-intensity physical exercise (HIPE) showed a significant advantage only in reducing the odds of the metabolic-cardiovascular disease class by 18%–23% (unweighted OR 0.77, 95% CI 0.62–0.97; weighted OR 0.82, 95% CI 0.71–0.95). …”
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Effect of yellow rice wine on anti-aging ability in aged mice induced by d-galactose
Published 2020-06-01Get full text
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PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma
Published 2025-01-01Get full text
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