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Crystal structure of 6-(pyridin-3-yl)-1,3,5-triazine-2,4-diamine-sebacic acid (2/1), C13H17N6O2
Published 2023-10-01Get full text
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The Association of Mitochondrial tRNACys G5783A Mutation with Major Depressive Disorder in Two Han Chinese Families
Published 2025-01-01“…Pan Jing,1,2 Haihang Yu,1,2 Wenxi Sun,3,4 Ming Liang,5 Tingting Xia,5 Haidong Yang,6 Peng Chen,3,4 Jin Li,3,4 Xiaobin Zhang3,4 1Department of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of psychiatry, Ningbo Kangning Hospital, Ningbo, People’s Republic of China; 3Department of Psychiatry, Suzhou Guangji Hospital, Suzhou, People’s Republic of China; 4Department of Psychiatry, Affiliated Guangji Hospital of Soochow University, Suzhou, People’s Republic of China; 5Department of Psychiatry, Xiangshan Third People’s Hospital, Ningbo, People’s Republic of China; 6Department of Psychiatry, Lianyungang Fourth People’s Hospital, Lianyungang, People’s Republic of ChinaCorrespondence: Xiaobin Zhang, Department of Psychiatric, Suzhou Guangji Hospital, 11 Guangqian Road, Suzhou, Jiangsu, 215003, People’s Republic of China, Email zhangxiaobim@163.comObjective: In this study, we examined the genetic, medical, and molecular traits of two Han Chinese families with the tRNACys G5783A mutation to investigate the relationship between mitochondrial DNA (mtDNA) mutations and major depressive disorder (MDD).Methods: Clinical data and comprehensive mitochondrial genomes were collected from the two families. …”
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RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis
Published 2025-02-01“…Yuting Qin,1,* Shuanglin Liao,1,* Jianbo Sun,2 Huiyun Ye,1 Jiafu Li,1 Jiahui Pan,1 Junbing He,3 Zhengyuan Xia,4,5 Yiming Shao1,6 1Dongguan Key Laboratory of Sepsis Translational Medicine, The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 2Dongguan Key Laboratory of Chronic Inflammatory Diseases, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 3The Key Laboratory of Organ Dysfunction and Protection Translational Medicine, Jieyang Medical Research Center, Jieyang People’s Hospital, Jieyang, Guangdong, People’s Republic of China; 4Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China; 5State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 6The Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yiming Shao, Dongguan Key Laboratory of Sepsis Translational Medicine, the Intensive Care Unit,The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road 42, Tangxia Town, Dongguan, Guangdong Province, 523710, People’s Republic of China, Tel +86 18826690188, Email sym@gdmu.edu.cn Zhengyuan Xia, Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China, Tel +852-68798794, Email zyxia@hku.hkAbstract: Reversion inducing cysteine rich protein with kazal motifs (RECK), a Kazal motif-containing protein, regulates pro-inflammatory cytokines production, migration of inflammatory cells, vascular endothelial growth factor (VEGF) and Wnt pathways and plays critical roles in septic inflammatory storms and vascular endothelial dysfunction. …”
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Polyethylene Glycol Loxenatide (PEX-168) Reduces Body Weight and Blood Glucose in Simple Obese Mice
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Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway
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A transforming interpenetrating-phase cermet with high strength and energy dissipation capacity
Published 2025-01-01Get full text
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