Delta-opioid receptor signaling alleviates neuropathology and cognitive impairment in the mouse model of Alzheimer’s disease by regulating microglia homeostasis and inhibiting HMGB... by Yuan Xu, Naiyuan Shao, Feng Zhi, Ronghua Chen, Yilin Yang, Jiahui Li, Ying Xia, Ya Peng

Get full text

Decreased Expression of CD14 in MSU-Mediated Inflammation May Be Associated with Spontaneous Remission of Acute Gout by Lihua Duan, Jiao Luo, Qiang Fu, Ke Shang, Yingying Wei, Youlian Wang, Yan Li, Jie Chen

Get full text

The IL-10/STAT3 Axis Nasopharyngeal Carcinoma Cancer stem cell and radio resistance by Li-jun Wang, Ying Zhao, Yan-sheng Wang, Lei Xing, Yun-jing Duan, Huan-huan Zang

Get full text

Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease by Guoqing Zhang, Hongyan Luo, Xiaohua Lu, Yonghua Liu, Mei Wang, Bo Li, Haixia Lu, Yali Zheng

Get full text

Functional Connectivity Alterations Associated with COVID-19-Related Sleep Problems: A Longitudinal Resting-State fMRI Study by Chen HB, Li L, Sun YK, Liu Y, Chen W, Liu P, Liao YH, Xie A

“…Hao-bo Chen,1,* Ling Li,2,* Yun-kai Sun,2 Yi Liu,2 Wei Chen,3 Peng Liu,1 Yan-Hui Liao,1,2 An Xie1 1Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), Changsha, Hunan, People’s Republic of China; 2Department of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 3MR Research Collaboration Team, Siemens Healthineers Ltd., Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: An Xie, Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), 61 Jiefang West Road, Changsha, Hunan, 410005, People’s Republic of China, Tel/Fax +86-0731-81866132, Email xiean@hunnu.edu.cn Yan-Hui Liao, Department of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, Zhejiang, 310016, People’s Republic of China, Email liaoyanhui@zju.edu.cnBackground: COVID-19 has led to reports of fatigue and sleep problems. …”
Get full text

Application of Targeted Next-Generation Sequencing in Bronchoalveolar Lavage Fluid for the Detection of Pathogens in Pulmonary Infections by Dai X, Xu K, Tong Y, Li J, Dai L, Shi J, Xie H, Chen X

“…Xianning Dai,1 Kai Xu,1 Yu Tong,1 Jing Li,2 Liya Dai,1 Jianyou Shi,1 Haibin Xie,3 Xi Chen3 1Department of Clinical Laboratory, Wenzhou People’s Hospital, Wenzhou Maternal and Child Health Care Hospital, Zhejiang, People’s Republic of China; 2Department of PCCM, Wenzhou People’s Hospital, Wenzhou Maternal and Child Health Care Hospital, Zhejiang, People’s Republic of China; 3Department of Immunization Planning, Prevention and Health Care, Centers for Disease Control of Luchen, Zhejiang, People’s Republic of ChinaCorrespondence: Xi Chen, Department of Immunization Planning, Prevention and health care,Centers for Disease Control of Luchen, No. 3320 Guojing Road, Wenzhou, Zhejiang, 325005, People’s Republic of China, Tel +86 577 56760657, Fax +86 577 56760654, Email cxbrook0577@163.comObjective: This study aims to evaluate the utility of targeted next-generation sequencing (tNGS) in bronchoalveolar lavage fluid (BALF) for hospitalized patients with pulmonary infections.Methods: A cohort of 358 patients who received diagnosis and treatment for respiratory infections in the department of Respiratory Medicine at Wenzhou People’s hospital from January 2023 to April 2024 were selected for this study. …”
Get full text

Association of glucose to lymphocyte ratio with the risk of death in patients with atherosclerotic cardiovascular disease by Jinglin Lei, Wentao Duan, Xiaoxi Yao, Zheng Hu, Huihui Fan, Yifan Liu, Wenjian Zhong, Haipeng Li

Get full text

CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

Get full text

Transcatheter Closure of Perimembranous and Intracristal Ventricular Septal Defects Using Amplatzer Duct Occluder II in Children by Shenrong Liu, Wenqian Zhang, Junjie Li, Shushui Wang, Mingyang Qian, Jijun Shi, Yumei Xie, Zhiwei Zhang

Get full text

Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms by Xiao Wang, Wenxuan Shi, Yu Jin, Zhuoyuan Li, Tanjun Deng, Tingshu Su, Ao Zheng, Lingyan Cao

Get full text

Postoperative evaluation of visual and cognitive functions following cataract surgery in patients with age-related cataracts: a prospective longitudinal study by Chenzhu Zhao, Chenzhu Zhao, Xuan Li, Bolin Deng, Bingyue Shui, Lin Zhou, Zhengzheng Wu, Zhengzheng Wu

Get full text

REDD1 mediates HDM-induced nuclear-cytoplasmic translocation and release of IL-33 in airway epithelial cells by downregulating Nrf2 by Tian Luo, Wentao Ji, Yuxin Gong, Lichang Chen, Chao Liu, Dandan Zhang, Xi Li, Yanhua Lv

Get full text

The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population by Li Jin, Tao Wang, Song Jiang, Miao Chen, Rong Zhang, Cheng Hu, Weiping Jia, Zhihong Liu

Get full text

CircSPG21 ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells and mitigates intervertebral disc degeneration through the miR-217/SIRT... by Yongbo Zhang, Sheng Yang, Xuan You, Zhengguang Li, Liuyang chen, Rui Dai, Hua Sun, Liang Zhang

Get full text

Short-Term Results of Switch from Conbercept to Bevacizumab or Ranibizumab in Eyes with Persistent Neovascular Age-Related Macular Degeneration by Zongyi Wang, Mengyang Li, Yuou Yao, Jie Hu, Jiyang Tang, Ran Tang, Zhenyu Piao, Jinfeng Qu

Get full text

Association of genetic variations in the NOS1 gene with insomnia, sleep duration and obstructive sleep apnea-related clinical quantitative traits by YUAN Haolin, LI Niannian, HU Junhui, SHEN Jinhong, GAO Zhenfei, GUAN Jian, LIU Feng, YIN Shankai

Get full text

Pan-cancer and experimental analyses reveal the immunotherapeutic significance of CST2 and its association with stomach adenocarcinoma proliferation and metastasis by Dan Huang, Jing Li, Zhijun He, Wenjing Liang, Likun Zhong, Jun Huang, Yinteng Wu, Shijian Zhao

Get full text

A Commentary on “Effective Dose of Epidural Hydromorphone for Analgesia Following Caesarean Section in Using Modified Dixon Sequential Method” [Response to Letter] by Liu QQ, Mao M, Lin NH, Xu CY, Li Q, Jiang CS, Feng SW, Yuan HM

“…Qiao-Qiao Liu,1,* Mao Mao,1,* Ning-Hua Lin,2,* Chen-Yang Xu,1,* Qian Li,1 Chang-Shuo Jiang,1 Shan-Wu Feng,1 Hong-Mei Yuan1 1Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, Nanjing, 210004, People’s Republic of China; 2Department of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shan-Wu Feng; Hong-Mei Yuan, Department of Anesthesiology, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, No. 123, Tianfei Lane, Mochou Road, Nanjing, Jiangsu, People’s Republic of China, Email Shanwufeng666@163.com; yuanhm667@126.com…”
Get full text

Complex adaptive systems science in the era of global sustainability crisis by Li An, B.L. Turner, II, Jianguo Liu, Volker Grimm, Qi Zhang, Zhangyang Wang, Ruihong Huang

Get full text

Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process by Guo-Ping Chen, Xiao-Qin Zhang, Tao Wu, Liang Li, Jie Han, Chang-Qing Du

Get full text